PhosphoNET

           
Protein Info 
   
Short Name:  Rdh8
Full Name:  Retinol dehydrogenase 8
Alias:  Photoreceptor outer segment all-trans retinol dehydrogenase; Prrdh; Retinol dehydrogenase 8 (all-trans); Sdr28c2; Short chain dehydrogenase/reductase family 28C, member 2
Type:  EC 1.1.1.-; Membrane protein, integral; Oxidoreductase; Cofactor and Vitamin Metabolism - retinol
Mass (Da):  33737
Number AA:  311
UniProt ID:  Q9NYR8
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005887   Uniprot OncoNet
Molecular Function:  GO:0005488  GO:0004303  GO:0004745 PhosphoSite+ KinaseNET
Biological Process:  GO:0006703  GO:0055114  GO:0050896 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S15VLISGCSSGIGLELA
Site 2Y33AHDPKKRYQVVATMR
Site 3T38KRYQVVATMRDLGKK
Site 4T208SMAEFPGTDPETLHY
Site 5T212FPGTDPETLHYFRDL
Site 6Y215TDPETLHYFRDLYLP
Site 7Y220LHYFRDLYLPASRKL
Site 8S224RDLYLPASRKLFCSV
Site 9S230ASRKLFCSVGQNPQD
Site 10S247QAIVNVISSTRPPLR
Site 11S248AIVNVISSTRPPLRR
Site 12T257RPPLRRQTNIRYSPL
Site 13S262RQTNIRYSPLTTLKT
Site 14T265NIRYSPLTTLKTVDS
Site 15T266IRYSPLTTLKTVDSS
Site 16T269SPLTTLKTVDSSGSL
Site 17S272TTLKTVDSSGSLYVR
Site 18S273TLKTVDSSGSLYVRT
Site 19S275KTVDSSGSLYVRTTH
Site 20Y277VDSSGSLYVRTTHRL
Site 21T280SGSLYVRTTHRLLFR
Site 22T281GSLYVRTTHRLLFRC
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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