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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CELSR3
Full Name:
Cadherin EGF LAG seven-pass G-type receptor 3
Alias:
Anchor protein; Cadherin EGF LAG seven-pass G-type receptor 3; Cadherin EGF LAG seven-pass G-type receptor 3, flamingo (Drosophila) homolog; Cadherin family member 11; Cadherin, EGF LAG seven-pass G-type receptor 3; Cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila); CDHF11; CELR3; EGFL1; EGF-like-domain, multiple 1; Epidermal growth factor-like 1; Epidermal growth factor-like protein 1; Flamingo homolog 1; FMI1; HFmi1; KIAA0812; MEGF2; Multiple EGF-like domains 2; Multiple epidermal growth factor-like domains 2; Multiple epidermal growth factor-like domains protein 2; RESDA1
Type:
Receptor, GPCR
Mass (Da):
358185
Number AA:
3312
UniProt ID:
Q9NYQ7
International Prot ID:
IPI00015345
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004930
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007156
GO:0007218
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S68
L
A
L
C
P
E
S
S
G
V
R
E
D
G
G
Site 2
S94
G
L
R
G
R
R
Q
S
A
R
N
S
R
G
P
Site 3
S98
R
R
Q
S
A
R
N
S
R
G
P
P
E
Q
P
Site 4
S120
H
G
V
Q
P
L
G
S
R
E
R
E
T
G
Q
Site 5
T125
L
G
S
R
E
R
E
T
G
Q
G
P
G
S
V
Site 6
S131
E
T
G
Q
G
P
G
S
V
L
Y
W
R
P
E
Site 7
Y134
Q
G
P
G
S
V
L
Y
W
R
P
E
V
S
S
Site 8
S140
L
Y
W
R
P
E
V
S
S
C
G
R
T
G
P
Site 9
S141
Y
W
R
P
E
V
S
S
C
G
R
T
G
P
L
Site 10
T145
E
V
S
S
C
G
R
T
G
P
L
Q
R
G
S
Site 11
S152
T
G
P
L
Q
R
G
S
L
S
P
G
A
L
S
Site 12
S154
P
L
Q
R
G
S
L
S
P
G
A
L
S
S
G
Site 13
S160
L
S
P
G
A
L
S
S
G
V
P
G
S
G
N
Site 14
S165
L
S
S
G
V
P
G
S
G
N
S
S
P
L
P
Site 15
S169
V
P
G
S
G
N
S
S
P
L
P
S
D
F
L
Site 16
S173
G
N
S
S
P
L
P
S
D
F
L
I
R
H
H
Site 17
S186
H
H
G
P
K
P
V
S
S
Q
R
N
A
G
T
Site 18
S187
H
G
P
K
P
V
S
S
Q
R
N
A
G
T
G
Site 19
T193
S
S
Q
R
N
A
G
T
G
S
R
K
R
V
G
Site 20
S195
Q
R
N
A
G
T
G
S
R
K
R
V
G
T
A
Site 21
T201
G
S
R
K
R
V
G
T
A
R
C
C
G
E
L
Site 22
T211
C
C
G
E
L
W
A
T
G
S
K
G
Q
G
E
Site 23
S213
G
E
L
W
A
T
G
S
K
G
Q
G
E
R
A
Site 24
T221
K
G
Q
G
E
R
A
T
T
S
G
A
E
R
T
Site 25
T222
G
Q
G
E
R
A
T
T
S
G
A
E
R
T
A
Site 26
S223
Q
G
E
R
A
T
T
S
G
A
E
R
T
A
P
Site 27
S239
R
N
C
L
P
G
A
S
G
S
G
P
E
L
D
Site 28
S241
C
L
P
G
A
S
G
S
G
P
E
L
D
S
A
Site 29
S247
G
S
G
P
E
L
D
S
A
P
R
T
A
R
T
Site 30
T251
E
L
D
S
A
P
R
T
A
R
T
A
P
A
S
Site 31
T254
S
A
P
R
T
A
R
T
A
P
A
S
G
S
A
Site 32
S258
T
A
R
T
A
P
A
S
G
S
A
P
R
E
S
Site 33
S260
R
T
A
P
A
S
G
S
A
P
R
E
S
R
T
Site 34
S265
S
G
S
A
P
R
E
S
R
T
A
P
E
P
A
Site 35
S278
P
A
P
K
R
M
R
S
R
G
L
F
R
C
R
Site 36
T308
R
P
E
A
R
K
V
T
S
A
N
R
A
R
F
Site 37
Y328
R
H
P
Q
F
P
Q
Y
N
Y
Q
T
L
V
P
Site 38
Y330
P
Q
F
P
Q
Y
N
Y
Q
T
L
V
P
E
N
Site 39
T332
F
P
Q
Y
N
Y
Q
T
L
V
P
E
N
E
A
Site 40
S370
S
L
A
A
L
M
N
S
R
S
L
E
L
F
S
Site 41
S377
S
R
S
L
E
L
F
S
I
D
P
Q
S
G
L
Site 42
S395
A
A
A
L
D
R
E
S
M
E
R
H
Y
L
R
Site 43
Y400
R
E
S
M
E
R
H
Y
L
R
V
T
A
Q
D
Site 44
T404
E
R
H
Y
L
R
V
T
A
Q
D
H
G
S
P
Site 45
S410
V
T
A
Q
D
H
G
S
P
R
L
S
A
T
T
Site 46
S414
D
H
G
S
P
R
L
S
A
T
T
M
V
A
V
Site 47
T422
A
T
T
M
V
A
V
T
V
A
D
R
N
D
H
Site 48
S430
V
A
D
R
N
D
H
S
P
V
F
E
Q
A
Q
Site 49
Y438
P
V
F
E
Q
A
Q
Y
R
E
T
L
R
E
N
Site 50
T441
E
Q
A
Q
Y
R
E
T
L
R
E
N
V
E
E
Site 51
Y450
R
E
N
V
E
E
G
Y
P
I
L
Q
L
R
A
Site 52
T458
P
I
L
Q
L
R
A
T
D
G
D
A
P
P
N
Site 53
Y470
P
P
N
A
N
L
R
Y
R
F
V
G
P
P
A
Site 54
S492
A
F
E
I
D
P
R
S
G
L
I
S
T
S
G
Site 55
S496
D
P
R
S
G
L
I
S
T
S
G
R
V
D
R
Site 56
S498
R
S
G
L
I
S
T
S
G
R
V
D
R
E
H
Site 57
S508
V
D
R
E
H
M
E
S
Y
E
L
V
V
E
A
Site 58
S516
Y
E
L
V
V
E
A
S
D
Q
G
Q
E
P
G
Site 59
S526
G
Q
E
P
G
P
R
S
A
T
V
R
V
H
I
Site 60
T528
E
P
G
P
R
S
A
T
V
R
V
H
I
T
V
Site 61
T534
A
T
V
R
V
H
I
T
V
L
D
E
N
D
N
Site 62
Y550
P
Q
F
S
E
K
R
Y
V
A
Q
V
R
E
D
Site 63
T562
R
E
D
V
R
P
H
T
V
V
L
R
V
T
A
Site 64
T568
H
T
V
V
L
R
V
T
A
T
D
R
D
K
D
Site 65
T570
V
V
L
R
V
T
A
T
D
R
D
K
D
A
N
Site 66
Y582
D
A
N
G
L
V
H
Y
N
I
I
S
G
N
S
Site 67
S597
R
G
H
F
A
I
D
S
L
T
G
E
I
Q
V
Site 68
Y616
D
F
E
A
E
R
E
Y
A
L
R
I
R
A
Q
Site 69
S631
D
A
G
R
P
P
L
S
N
N
T
G
L
A
S
Site 70
Y688
G
E
N
A
R
L
E
Y
S
L
T
G
V
A
P
Site 71
S689
E
N
A
R
L
E
Y
S
L
T
G
V
A
P
D
Site 72
T691
A
R
L
E
Y
S
L
T
G
V
A
P
D
T
P
Site 73
S709
N
S
A
T
G
W
V
S
V
S
G
P
L
D
R
Site 74
S711
A
T
G
W
V
S
V
S
G
P
L
D
R
E
S
Site 75
S718
S
G
P
L
D
R
E
S
V
E
H
Y
F
F
G
Site 76
Y722
D
R
E
S
V
E
H
Y
F
F
G
V
E
A
R
Site 77
S733
V
E
A
R
D
H
G
S
P
P
L
S
A
S
A
Site 78
S737
D
H
G
S
P
P
L
S
A
S
A
S
V
T
V
Site 79
S787
A
V
D
R
D
A
N
S
A
I
S
Y
Q
I
T
Site 80
S790
R
D
A
N
S
A
I
S
Y
Q
I
T
G
G
N
Site 81
Y791
D
A
N
S
A
I
S
Y
Q
I
T
G
G
N
T
Site 82
T794
S
A
I
S
Y
Q
I
T
G
G
N
T
R
N
R
Site 83
S805
T
R
N
R
F
A
I
S
T
Q
G
G
V
G
L
Site 84
T806
R
N
R
F
A
I
S
T
Q
G
G
V
G
L
V
Site 85
Y821
T
L
A
L
P
L
D
Y
K
Q
E
R
Y
F
K
Site 86
Y826
L
D
Y
K
Q
E
R
Y
F
K
L
V
L
T
A
Site 87
T832
R
Y
F
K
L
V
L
T
A
S
D
R
A
L
H
Site 88
S834
F
K
L
V
L
T
A
S
D
R
A
L
H
D
H
Site 89
T853
I
N
I
T
D
A
N
T
H
R
P
V
F
Q
S
Site 90
S860
T
H
R
P
V
F
Q
S
A
H
Y
S
V
S
V
Site 91
S864
V
F
Q
S
A
H
Y
S
V
S
V
N
E
D
R
Site 92
T894
V
G
E
N
A
R
I
T
Y
L
L
E
D
N
L
Site 93
Y895
G
E
N
A
R
I
T
Y
L
L
E
D
N
L
P
Site 94
S910
Q
F
R
I
D
A
D
S
G
A
I
T
L
Q
A
Site 95
T914
D
A
D
S
G
A
I
T
L
Q
A
P
L
D
Y
Site 96
Y921
T
L
Q
A
P
L
D
Y
E
D
Q
V
T
Y
T
Site 97
Y946
P
Q
K
A
D
T
T
Y
V
E
V
M
V
N
D
Site 98
T986
S
V
L
Q
I
S
A
T
D
R
D
A
H
A
N
Site 99
Y998
H
A
N
G
R
V
Q
Y
T
F
Q
N
G
E
D
Site 100
T999
A
N
G
R
V
Q
Y
T
F
Q
N
G
E
D
G
Site 101
T1011
E
D
G
D
G
D
F
T
I
E
P
T
S
G
I
Site 102
S1016
D
F
T
I
E
P
T
S
G
I
V
R
T
V
R
Site 103
T1021
P
T
S
G
I
V
R
T
V
R
R
L
D
R
E
Site 104
S1031
R
L
D
R
E
A
V
S
V
Y
E
L
T
A
Y
Site 105
Y1104
G
P
N
A
H
I
M
Y
Q
I
V
E
G
N
I
Site 106
Y1132
T
A
L
I
D
L
D
Y
E
A
R
Q
E
Y
V
Site 107
Y1138
D
Y
E
A
R
Q
E
Y
V
I
V
V
Q
A
T
Site 108
S1166
L
V
D
Q
N
D
N
S
P
V
L
N
N
F
Q
Site 109
Y1179
F
Q
I
L
F
N
N
Y
V
S
N
R
S
D
T
Site 110
T1186
Y
V
S
N
R
S
D
T
F
P
S
G
I
I
G
Site 111
Y1198
I
I
G
R
I
P
A
Y
D
P
D
V
S
D
H
Site 112
S1203
P
A
Y
D
P
D
V
S
D
H
L
F
Y
S
F
Site 113
Y1208
D
V
S
D
H
L
F
Y
S
F
E
R
G
N
E
Site 114
S1209
V
S
D
H
L
F
Y
S
F
E
R
G
N
E
L
Site 115
S1231
T
S
G
E
L
R
L
S
R
K
L
D
N
N
R
Site 116
S1349
A
A
G
P
W
F
S
S
E
E
L
Q
E
Q
L
Site 117
Y1357
E
E
L
Q
E
Q
L
Y
V
R
R
A
A
L
A
Site 118
Y1387
L
R
E
P
C
E
N
Y
M
K
C
V
S
V
L
Site 119
S1392
E
N
Y
M
K
C
V
S
V
L
R
F
D
S
S
Site 120
Y1440
E
T
E
L
D
L
C
Y
S
N
P
C
R
N
G
Site 121
Y1457
C
A
R
R
E
G
G
Y
T
C
V
C
R
P
R
Site 122
T1458
A
R
R
E
G
G
Y
T
C
V
C
R
P
R
F
Site 123
T1466
C
V
C
R
P
R
F
T
G
E
D
C
E
L
D
Site 124
T1474
G
E
D
C
E
L
D
T
E
A
G
R
C
V
P
Site 125
S1519
R
C
E
V
A
A
R
S
F
P
P
S
S
F
V
Site 126
T1577
V
A
G
Q
V
R
L
T
Y
S
T
G
E
S
N
Site 127
Y1578
A
G
Q
V
R
L
T
Y
S
T
G
E
S
N
T
Site 128
S1579
G
Q
V
R
L
T
Y
S
T
G
E
S
N
T
V
Site 129
T1580
Q
V
R
L
T
Y
S
T
G
E
S
N
T
V
V
Site 130
S1583
L
T
Y
S
T
G
E
S
N
T
V
V
S
P
T
Site 131
T1585
Y
S
T
G
E
S
N
T
V
V
S
P
T
V
P
Site 132
S1588
G
E
S
N
T
V
V
S
P
T
V
P
G
G
L
Site 133
T1590
S
N
T
V
V
S
P
T
V
P
G
G
L
S
D
Site 134
Y1608
H
T
V
H
L
R
Y
Y
N
K
P
R
T
D
A
Site 135
T1613
R
Y
Y
N
K
P
R
T
D
A
L
G
G
A
Q
Site 136
S1660
A
A
A
G
V
Q
T
S
S
K
K
S
L
D
L
Site 137
S1664
V
Q
T
S
S
K
K
S
L
D
L
T
G
P
L
Site 138
S1728
A
K
L
H
F
C
D
S
G
P
C
K
N
S
G
Site 139
S1811
Q
V
Q
A
G
P
H
S
T
L
L
C
Q
L
D
Site 140
S1823
Q
L
D
R
G
L
L
S
V
T
V
T
R
G
S
Site 141
T1825
D
R
G
L
L
S
V
T
V
T
R
G
S
G
R
Site 142
S1830
S
V
T
V
T
R
G
S
G
R
A
S
H
L
L
Site 143
S1834
T
R
G
S
G
R
A
S
H
L
L
L
D
Q
V
Site 144
T1842
H
L
L
L
D
Q
V
T
V
S
D
G
R
W
H
Site 145
S1904
V
G
G
L
P
P
G
S
A
E
E
A
P
Q
G
Site 146
S1923
I
Q
G
V
W
L
G
S
T
P
S
G
S
P
A
Site 147
T1924
Q
G
V
W
L
G
S
T
P
S
G
S
P
A
L
Site 148
S1928
L
G
S
T
P
S
G
S
P
A
L
L
P
P
S
Site 149
S1935
S
P
A
L
L
P
P
S
H
R
V
N
A
E
P
Site 150
Y1976
S
C
T
C
Q
P
G
Y
Y
G
P
G
C
V
D
Site 151
Y2066
C
H
C
K
E
F
H
Y
R
P
R
G
S
D
S
Site 152
S2071
F
H
Y
R
P
R
G
S
D
S
C
L
P
C
D
Site 153
Y2080
S
C
L
P
C
D
C
Y
P
V
G
S
T
S
R
Site 154
S2084
C
D
C
Y
P
V
G
S
T
S
R
S
C
A
P
Site 155
S2086
C
Y
P
V
G
S
T
S
R
S
C
A
P
H
S
Site 156
S2088
P
V
G
S
T
S
R
S
C
A
P
H
S
G
Q
Site 157
S2093
S
R
S
C
A
P
H
S
G
Q
C
P
C
R
P
Site 158
S2112
R
Q
C
N
S
C
D
S
P
F
A
E
V
T
A
Site 159
T2149
T
K
F
G
V
L
A
T
V
P
C
P
R
G
A
Site 160
S2180
P
D
L
F
N
C
T
S
P
A
F
R
E
L
S
Site 161
T2198
D
G
L
E
L
N
K
T
A
L
D
T
M
E
A
Site 162
T2216
A
Q
R
L
R
E
V
T
G
H
T
D
H
Y
F
Site 163
Y2222
V
T
G
H
T
D
H
Y
F
S
Q
D
V
R
V
Site 164
S2224
G
H
T
D
H
Y
F
S
Q
D
V
R
V
T
A
Site 165
S2288
G
Q
R
A
P
G
G
S
P
G
S
A
G
L
V
Site 166
S2291
A
P
G
G
S
P
G
S
A
G
L
V
R
H
L
Site 167
Y2301
L
V
R
H
L
E
E
Y
A
A
T
L
A
R
N
Site 168
T2304
H
L
E
E
Y
A
A
T
L
A
R
N
M
E
L
Site 169
S2327
V
T
P
N
I
M
L
S
I
D
R
M
E
H
P
Site 170
S2335
I
D
R
M
E
H
P
S
S
P
R
G
A
R
R
Site 171
S2336
D
R
M
E
H
P
S
S
P
R
G
A
R
R
Y
Site 172
Y2343
S
P
R
G
A
R
R
Y
P
R
Y
H
S
N
L
Site 173
Y2346
G
A
R
R
Y
P
R
Y
H
S
N
L
F
R
G
Site 174
S2348
R
R
Y
P
R
Y
H
S
N
L
F
R
G
Q
D
Site 175
T2361
Q
D
A
W
D
P
H
T
H
V
L
L
P
S
Q
Site 176
S2367
H
T
H
V
L
L
P
S
Q
S
P
R
P
S
P
Site 177
S2369
H
V
L
L
P
S
Q
S
P
R
P
S
P
S
E
Site 178
S2373
P
S
Q
S
P
R
P
S
P
S
E
V
L
P
T
Site 179
S2375
Q
S
P
R
P
S
P
S
E
V
L
P
T
S
S
Site 180
T2380
S
P
S
E
V
L
P
T
S
S
S
I
E
N
S
Site 181
S2381
P
S
E
V
L
P
T
S
S
S
I
E
N
S
T
Site 182
S2383
E
V
L
P
T
S
S
S
I
E
N
S
T
T
S
Site 183
S2387
T
S
S
S
I
E
N
S
T
T
S
S
V
V
P
Site 184
T2389
S
S
I
E
N
S
T
T
S
S
V
V
P
P
P
Site 185
S2391
I
E
N
S
T
T
S
S
V
V
P
P
P
A
P
Site 186
T2472
L
E
F
R
L
L
Q
T
A
N
R
S
K
A
I
Site 187
S2508
E
L
V
H
R
N
G
S
H
A
R
C
R
C
S
Site 188
S2515
S
H
A
R
C
R
C
S
R
T
G
T
F
G
V
Site 189
T2519
C
R
C
S
R
T
G
T
F
G
V
L
M
D
A
Site 190
S2527
F
G
V
L
M
D
A
S
P
R
E
R
L
E
G
Site 191
S2569
L
S
L
R
S
L
K
S
N
V
R
G
I
H
A
Site 192
Y2628
F
V
Q
G
L
H
L
Y
R
M
Q
V
E
P
R
Site 193
Y2645
D
R
G
A
M
R
F
Y
H
A
L
G
W
G
V
Site 194
Y2668
V
G
L
D
P
E
G
Y
G
N
P
D
F
C
W
Site 195
S2708
F
L
L
A
A
R
T
S
C
S
T
G
Q
R
E
Site 196
T2711
A
A
R
T
S
C
S
T
G
Q
R
E
A
K
K
Site 197
T2719
G
Q
R
E
A
K
K
T
S
A
L
T
L
R
S
Site 198
Y2807
P
G
L
G
P
G
A
Y
N
N
T
A
L
F
E
Site 199
S2826
I
R
I
T
L
G
A
S
T
V
S
S
V
S
S
Site 200
S2829
T
L
G
A
S
T
V
S
S
V
S
S
A
R
S
Site 201
S2830
L
G
A
S
T
V
S
S
V
S
S
A
R
S
G
Site 202
S2832
A
S
T
V
S
S
V
S
S
A
R
S
G
R
T
Site 203
S2833
S
T
V
S
S
V
S
S
A
R
S
G
R
T
Q
Site 204
S2836
S
S
V
S
S
A
R
S
G
R
T
Q
D
Q
D
Site 205
S2844
G
R
T
Q
D
Q
D
S
Q
R
G
R
S
Y
L
Site 206
S2849
Q
D
S
Q
R
G
R
S
Y
L
R
D
N
V
L
Site 207
Y2850
D
S
Q
R
G
R
S
Y
L
R
D
N
V
L
V
Site 208
S2861
N
V
L
V
R
H
G
S
A
A
D
H
T
D
H
Site 209
T2866
H
G
S
A
A
D
H
T
D
H
S
L
Q
A
H
Site 210
S2869
A
A
D
H
T
D
H
S
L
Q
A
H
A
G
P
Site 211
S2892
H
R
D
A
G
A
D
S
D
S
D
S
D
L
S
Site 212
S2894
D
A
G
A
D
S
D
S
D
S
D
L
S
L
E
Site 213
S2896
G
A
D
S
D
S
D
S
D
L
S
L
E
E
E
Site 214
S2899
S
D
S
D
S
D
L
S
L
E
E
E
R
S
L
Site 215
S2905
L
S
L
E
E
E
R
S
L
S
I
P
S
S
E
Site 216
S2907
L
E
E
E
R
S
L
S
I
P
S
S
E
S
E
Site 217
S2911
R
S
L
S
I
P
S
S
E
S
E
D
N
G
R
Site 218
S2913
L
S
I
P
S
S
E
S
E
D
N
G
R
T
R
Site 219
S2933
P
L
C
R
A
A
Q
S
E
R
L
L
T
H
P
Site 220
T2938
A
Q
S
E
R
L
L
T
H
P
K
D
V
D
G
Site 221
S2950
V
D
G
N
D
L
L
S
Y
W
P
A
L
G
E
Site 222
Y2951
D
G
N
D
L
L
S
Y
W
P
A
L
G
E
C
Site 223
S2970
C
A
L
Q
T
W
G
S
E
R
R
L
G
L
D
Site 224
T2978
E
R
R
L
G
L
D
T
S
K
D
A
A
N
N
Site 225
S2979
R
R
L
G
L
D
T
S
K
D
A
A
N
N
N
Site 226
S2994
Q
P
D
P
A
L
T
S
G
D
E
T
S
L
G
Site 227
T2998
A
L
T
S
G
D
E
T
S
L
G
R
A
Q
R
Site 228
S2999
L
T
S
G
D
E
T
S
L
G
R
A
Q
R
Q
Site 229
Y3017
I
L
K
N
R
L
Q
Y
P
L
V
P
Q
T
R
Site 230
S3030
T
R
G
A
P
E
L
S
W
C
R
A
A
T
L
Site 231
S3046
H
R
A
V
P
A
A
S
Y
G
R
I
Y
A
G
Site 232
Y3047
R
A
V
P
A
A
S
Y
G
R
I
Y
A
G
G
Site 233
Y3051
A
A
S
Y
G
R
I
Y
A
G
G
G
T
G
S
Site 234
S3058
Y
A
G
G
G
T
G
S
L
S
Q
P
A
S
R
Site 235
S3060
G
G
G
T
G
S
L
S
Q
P
A
S
R
Y
S
Site 236
S3064
G
S
L
S
Q
P
A
S
R
Y
S
S
R
E
Q
Site 237
S3067
S
Q
P
A
S
R
Y
S
S
R
E
Q
L
D
L
Site 238
S3068
Q
P
A
S
R
Y
S
S
R
E
Q
L
D
L
L
Site 239
S3081
L
L
L
R
R
Q
L
S
R
E
R
L
E
E
A
Site 240
S3097
A
P
V
L
R
P
L
S
R
P
G
S
Q
E
C
Site 241
S3101
R
P
L
S
R
P
G
S
Q
E
C
M
D
A
A
Site 242
S3119
L
E
P
K
D
R
G
S
T
L
P
R
R
Q
P
Site 243
T3120
E
P
K
D
R
G
S
T
L
P
R
R
Q
P
P
Site 244
Y3130
R
R
Q
P
P
R
D
Y
P
G
A
M
A
G
R
Site 245
S3140
A
M
A
G
R
F
G
S
R
D
A
L
D
L
G
Site 246
S3154
G
A
P
R
E
W
L
S
T
L
P
P
P
R
R
Site 247
T3155
A
P
R
E
W
L
S
T
L
P
P
P
R
R
T
Site 248
T3162
T
L
P
P
P
R
R
T
R
D
L
D
P
Q
P
Site 249
S3175
Q
P
P
P
L
P
L
S
P
Q
R
Q
L
S
R
Site 250
S3181
L
S
P
Q
R
Q
L
S
R
D
P
L
L
P
S
Site 251
S3188
S
R
D
P
L
L
P
S
R
P
L
D
S
L
S
Site 252
S3193
L
P
S
R
P
L
D
S
L
S
R
S
S
N
S
Site 253
S3195
S
R
P
L
D
S
L
S
R
S
S
N
S
R
E
Site 254
S3197
P
L
D
S
L
S
R
S
S
N
S
R
E
Q
L
Site 255
S3198
L
D
S
L
S
R
S
S
N
S
R
E
Q
L
D
Site 256
S3209
E
Q
L
D
Q
V
P
S
R
H
P
S
R
E
A
Site 257
S3213
Q
V
P
S
R
H
P
S
R
E
A
L
G
P
L
Site 258
S3230
L
L
R
A
R
E
D
S
V
S
G
P
S
H
G
Site 259
S3232
R
A
R
E
D
S
V
S
G
P
S
H
G
P
S
Site 260
S3235
E
D
S
V
S
G
P
S
H
G
P
S
T
E
Q
Site 261
S3239
S
G
P
S
H
G
P
S
T
E
Q
L
D
I
L
Site 262
S3259
S
F
N
S
S
A
L
S
S
V
Q
S
S
S
T
Site 263
S3260
F
N
S
S
A
L
S
S
V
Q
S
S
S
T
P
Site 264
S3263
S
A
L
S
S
V
Q
S
S
S
T
P
L
G
P
Site 265
S3264
A
L
S
S
V
Q
S
S
S
T
P
L
G
P
H
Site 266
S3265
L
S
S
V
Q
S
S
S
T
P
L
G
P
H
T
Site 267
T3266
S
S
V
Q
S
S
S
T
P
L
G
P
H
T
T
Site 268
T3272
S
T
P
L
G
P
H
T
T
A
T
P
S
A
T
Site 269
T3273
T
P
L
G
P
H
T
T
A
T
P
S
A
T
A
Site 270
S3286
T
A
S
V
L
G
P
S
T
P
R
S
A
T
S
Site 271
T3287
A
S
V
L
G
P
S
T
P
R
S
A
T
S
H
Site 272
S3290
L
G
P
S
T
P
R
S
A
T
S
H
S
I
S
Site 273
T3292
P
S
T
P
R
S
A
T
S
H
S
I
S
E
L
Site 274
S3293
S
T
P
R
S
A
T
S
H
S
I
S
E
L
S
Site 275
S3295
P
R
S
A
T
S
H
S
I
S
E
L
S
P
D
Site 276
S3297
S
A
T
S
H
S
I
S
E
L
S
P
D
S
E
Site 277
S3300
S
H
S
I
S
E
L
S
P
D
S
E
V
P
R
Site 278
S3303
I
S
E
L
S
P
D
S
E
V
P
R
S
E
G
Site 279
S3308
P
D
S
E
V
P
R
S
E
G
H
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation