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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C21orf45
Full Name:
Protein Mis18-alpha
Alias:
B28; C21orf46; Chromosome 21 open reading frame 45; CU045; FAPP1-associated 1; FAPP1-associated protein 1; FASP1
Type:
Mass (Da):
25863
Number AA:
233
UniProt ID:
Q9NYP9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000775
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0007067
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
G
V
R
S
L
R
C
S
R
G
C
A
G
G
C
Site 2
S26
C
G
D
K
G
K
C
S
D
S
S
L
L
G
K
Site 3
S28
D
K
G
K
C
S
D
S
S
L
L
G
K
R
L
Site 4
S29
K
G
K
C
S
D
S
S
L
L
G
K
R
L
S
Site 5
S36
S
L
L
G
K
R
L
S
E
D
S
S
R
H
Q
Site 6
S39
G
K
R
L
S
E
D
S
S
R
H
Q
L
L
Q
Site 7
S40
K
R
L
S
E
D
S
S
R
H
Q
L
L
Q
K
Site 8
S50
Q
L
L
Q
K
W
A
S
M
W
S
S
M
S
E
Site 9
S53
Q
K
W
A
S
M
W
S
S
M
S
E
D
A
S
Site 10
S54
K
W
A
S
M
W
S
S
M
S
E
D
A
S
V
Site 11
S56
A
S
M
W
S
S
M
S
E
D
A
S
V
A
D
Site 12
S60
S
S
M
S
E
D
A
S
V
A
D
M
E
R
A
Site 13
S95
C
R
R
P
L
G
D
S
L
S
W
V
A
S
Q
Site 14
S97
R
P
L
G
D
S
L
S
W
V
A
S
Q
E
D
Site 15
S101
D
S
L
S
W
V
A
S
Q
E
D
T
N
C
I
Site 16
S118
R
C
V
S
C
N
V
S
V
D
K
E
Q
K
L
Site 17
S126
V
D
K
E
Q
K
L
S
K
R
E
K
E
N
G
Site 18
Y150
G
C
S
L
N
L
G
Y
V
Y
R
C
T
P
K
Site 19
Y152
S
L
N
L
G
Y
V
Y
R
C
T
P
K
N
L
Site 20
T155
L
G
Y
V
Y
R
C
T
P
K
N
L
D
Y
K
Site 21
Y161
C
T
P
K
N
L
D
Y
K
R
D
L
F
C
L
Site 22
S169
K
R
D
L
F
C
L
S
V
E
A
I
E
S
Y
Site 23
Y176
S
V
E
A
I
E
S
Y
V
L
G
S
S
E
K
Site 24
S187
S
S
E
K
Q
I
V
S
E
D
K
E
L
F
N
Site 25
S197
K
E
L
F
N
L
E
S
R
V
E
I
E
K
S
Site 26
S204
S
R
V
E
I
E
K
S
L
T
Q
M
E
D
V
Site 27
T206
V
E
I
E
K
S
L
T
Q
M
E
D
V
L
K
Site 28
S224
M
K
L
W
E
A
E
S
K
L
S
F
A
T
C
Site 29
S227
W
E
A
E
S
K
L
S
F
A
T
C
K
S
_
Site 30
S233
L
S
F
A
T
C
K
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation