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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPP4R2
Full Name:
Serine/threonine-protein phosphatase 4 regulatory subunit 2
Alias:
MGC131930; PP4R2
Type:
Protein phosphatase, regulatory subunit
Mass (Da):
46898
Number AA:
417
UniProt ID:
Q9NY27
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005815
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0008380
GO:0006397
GO:0006464
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y48
Q
W
S
Q
F
K
G
Y
F
I
F
K
L
E
K
Site 2
T62
K
V
M
D
D
F
R
T
S
A
P
E
P
R
G
Site 3
S63
V
M
D
D
F
R
T
S
A
P
E
P
R
G
P
Site 4
Y77
P
P
N
P
N
V
E
Y
I
P
F
D
E
M
K
Site 5
T109
Q
R
L
C
E
L
L
T
D
P
R
R
N
Y
T
Site 6
Y115
L
T
D
P
R
R
N
Y
T
G
T
D
K
F
L
Site 7
T116
T
D
P
R
R
N
Y
T
G
T
D
K
F
L
R
Site 8
T118
P
R
R
N
Y
T
G
T
D
K
F
L
R
G
V
Site 9
S133
E
K
N
V
M
V
V
S
C
V
Y
P
S
S
E
Site 10
Y136
V
M
V
V
S
C
V
Y
P
S
S
E
K
N
N
Site 11
S139
V
S
C
V
Y
P
S
S
E
K
N
N
S
N
S
Site 12
S144
P
S
S
E
K
N
N
S
N
S
L
N
R
M
N
Site 13
S146
S
E
K
N
N
S
N
S
L
N
R
M
N
G
V
Site 14
S159
G
V
M
F
P
G
N
S
P
S
Y
T
E
R
S
Site 15
S161
M
F
P
G
N
S
P
S
Y
T
E
R
S
N
I
Site 16
Y162
F
P
G
N
S
P
S
Y
T
E
R
S
N
I
N
Site 17
T163
P
G
N
S
P
S
Y
T
E
R
S
N
I
N
G
Site 18
S166
S
P
S
Y
T
E
R
S
N
I
N
G
P
G
T
Site 19
T173
S
N
I
N
G
P
G
T
P
R
P
L
N
R
P
Site 20
S183
P
L
N
R
P
K
V
S
L
S
A
P
M
T
T
Site 21
S185
N
R
P
K
V
S
L
S
A
P
M
T
T
N
G
Site 22
T189
V
S
L
S
A
P
M
T
T
N
G
L
P
E
S
Site 23
T190
S
L
S
A
P
M
T
T
N
G
L
P
E
S
T
Site 24
S196
T
T
N
G
L
P
E
S
T
D
S
K
E
A
N
Site 25
S199
G
L
P
E
S
T
D
S
K
E
A
N
L
Q
Q
Site 26
S213
Q
N
E
E
K
N
H
S
D
S
S
T
S
E
S
Site 27
S215
E
E
K
N
H
S
D
S
S
T
S
E
S
E
V
Site 28
S216
E
K
N
H
S
D
S
S
T
S
E
S
E
V
S
Site 29
T217
K
N
H
S
D
S
S
T
S
E
S
E
V
S
S
Site 30
S218
N
H
S
D
S
S
T
S
E
S
E
V
S
S
V
Site 31
S220
S
D
S
S
T
S
E
S
E
V
S
S
V
S
P
Site 32
S223
S
T
S
E
S
E
V
S
S
V
S
P
L
K
N
Site 33
S224
T
S
E
S
E
V
S
S
V
S
P
L
K
N
K
Site 34
S226
E
S
E
V
S
S
V
S
P
L
K
N
K
H
P
Site 35
T259
K
E
G
E
V
R
E
T
A
S
Q
T
T
S
S
Site 36
S261
G
E
V
R
E
T
A
S
Q
T
T
S
S
E
I
Site 37
S265
E
T
A
S
Q
T
T
S
S
E
I
S
S
V
M
Site 38
S266
T
A
S
Q
T
T
S
S
E
I
S
S
V
M
V
Site 39
S269
Q
T
T
S
S
E
I
S
S
V
M
V
G
E
T
Site 40
S270
T
T
S
S
E
I
S
S
V
M
V
G
E
T
E
Site 41
T276
S
S
V
M
V
G
E
T
E
A
S
S
S
S
Q
Site 42
S279
M
V
G
E
T
E
A
S
S
S
S
Q
D
K
D
Site 43
S281
G
E
T
E
A
S
S
S
S
Q
D
K
D
K
D
Site 44
S311
D
E
E
E
E
E
E
S
F
M
T
S
R
E
M
Site 45
T314
E
E
E
E
S
F
M
T
S
R
E
M
I
P
E
Site 46
S315
E
E
E
S
F
M
T
S
R
E
M
I
P
E
R
Site 47
S329
R
K
N
Q
E
K
E
S
D
D
A
L
T
V
N
Site 48
T334
K
E
S
D
D
A
L
T
V
N
E
E
T
S
E
Site 49
S349
E
N
N
Q
M
E
E
S
D
V
S
Q
A
E
K
Site 50
S352
Q
M
E
E
S
D
V
S
Q
A
E
K
D
L
L
Site 51
S364
D
L
L
H
S
E
G
S
E
N
E
G
P
V
S
Site 52
S371
S
E
N
E
G
P
V
S
S
S
S
S
D
C
R
Site 53
S373
N
E
G
P
V
S
S
S
S
S
D
C
R
E
T
Site 54
S374
E
G
P
V
S
S
S
S
S
D
C
R
E
T
E
Site 55
S375
G
P
V
S
S
S
S
S
D
C
R
E
T
E
E
Site 56
T380
S
S
S
D
C
R
E
T
E
E
L
V
G
S
N
Site 57
S386
E
T
E
E
L
V
G
S
N
S
S
K
T
G
E
Site 58
S388
E
E
L
V
G
S
N
S
S
K
T
G
E
I
L
Site 59
S389
E
L
V
G
S
N
S
S
K
T
G
E
I
L
S
Site 60
T391
V
G
S
N
S
S
K
T
G
E
I
L
S
E
S
Site 61
S396
S
K
T
G
E
I
L
S
E
S
S
M
E
N
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation