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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC49
Full Name:
Pre-mRNA-splicing factor CWC25 homolog
Alias:
CCD49; Coiled-coil domain containing 49
Type:
Uncharacterized protein
Mass (Da):
49647
Number AA:
425
UniProt ID:
Q9NXE8
International Prot ID:
IPI00015618
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
G
D
L
N
L
K
K
S
W
H
P
Q
T
L
R
Site 2
T16
K
K
S
W
H
P
Q
T
L
R
N
V
E
K
V
Site 3
Y56
A
R
E
E
M
Q
R
Y
A
E
D
V
G
A
V
Site 4
Y74
E
E
K
L
D
W
M
Y
Q
G
P
G
G
M
V
Site 5
Y86
G
M
V
N
R
D
E
Y
L
L
G
R
P
I
D
Site 6
Y95
L
G
R
P
I
D
K
Y
V
F
E
K
M
E
E
Site 7
S108
E
E
K
E
A
G
C
S
S
E
T
G
L
L
P
Site 8
S109
E
K
E
A
G
C
S
S
E
T
G
L
L
P
G
Site 9
S126
F
A
P
S
G
A
N
S
L
L
D
M
A
S
K
Site 10
S132
N
S
L
L
D
M
A
S
K
I
R
E
D
P
L
Site 11
S193
H
K
K
H
K
H
R
S
S
S
S
D
R
S
S
Site 12
S194
K
K
H
K
H
R
S
S
S
S
D
R
S
S
S
Site 13
S195
K
H
K
H
R
S
S
S
S
D
R
S
S
S
E
Site 14
S196
H
K
H
R
S
S
S
S
D
R
S
S
S
E
D
Site 15
S199
R
S
S
S
S
D
R
S
S
S
E
D
E
H
S
Site 16
S200
S
S
S
S
D
R
S
S
S
E
D
E
H
S
A
Site 17
S201
S
S
S
D
R
S
S
S
E
D
E
H
S
A
G
Site 18
S206
S
S
S
E
D
E
H
S
A
G
R
S
Q
K
K
Site 19
S210
D
E
H
S
A
G
R
S
Q
K
K
M
A
N
S
Site 20
S217
S
Q
K
K
M
A
N
S
S
P
V
L
S
K
V
Site 21
S218
Q
K
K
M
A
N
S
S
P
V
L
S
K
V
P
Site 22
S222
A
N
S
S
P
V
L
S
K
V
P
G
Y
G
L
Site 23
Y227
V
L
S
K
V
P
G
Y
G
L
Q
V
R
N
S
Site 24
S234
Y
G
L
Q
V
R
N
S
D
R
N
Q
G
L
Q
Site 25
T245
Q
G
L
Q
G
P
L
T
A
E
Q
K
R
G
H
Site 26
S258
G
H
G
M
K
N
H
S
R
S
R
S
S
S
H
Site 27
S260
G
M
K
N
H
S
R
S
R
S
S
S
H
S
P
Site 28
S262
K
N
H
S
R
S
R
S
S
S
H
S
P
P
R
Site 29
S263
N
H
S
R
S
R
S
S
S
H
S
P
P
R
H
Site 30
S264
H
S
R
S
R
S
S
S
H
S
P
P
R
H
A
Site 31
S266
R
S
R
S
S
S
H
S
P
P
R
H
A
S
K
Site 32
S272
H
S
P
P
R
H
A
S
K
K
S
T
R
E
A
Site 33
S275
P
R
H
A
S
K
K
S
T
R
E
A
G
S
R
Site 34
T276
R
H
A
S
K
K
S
T
R
E
A
G
S
R
D
Site 35
S281
K
S
T
R
E
A
G
S
R
D
R
R
S
R
S
Site 36
S286
A
G
S
R
D
R
R
S
R
S
L
G
R
R
S
Site 37
S288
S
R
D
R
R
S
R
S
L
G
R
R
S
R
S
Site 38
S293
S
R
S
L
G
R
R
S
R
S
P
R
P
S
K
Site 39
S295
S
L
G
R
R
S
R
S
P
R
P
S
K
L
H
Site 40
S299
R
S
R
S
P
R
P
S
K
L
H
N
S
K
V
Site 41
T311
S
K
V
N
R
R
E
T
G
Q
T
R
S
P
S
Site 42
T314
N
R
R
E
T
G
Q
T
R
S
P
S
P
K
K
Site 43
S316
R
E
T
G
Q
T
R
S
P
S
P
K
K
E
V
Site 44
S318
T
G
Q
T
R
S
P
S
P
K
K
E
V
Y
Q
Site 45
Y324
P
S
P
K
K
E
V
Y
Q
R
R
H
A
P
G
Site 46
Y332
Q
R
R
H
A
P
G
Y
T
R
K
L
S
A
E
Site 47
S337
P
G
Y
T
R
K
L
S
A
E
E
L
E
R
K
Site 48
S381
Q
R
L
E
K
L
D
S
R
D
G
K
F
I
H
Site 49
S394
I
H
R
M
K
L
E
S
A
S
T
S
S
L
E
Site 50
S396
R
M
K
L
E
S
A
S
T
S
S
L
E
D
R
Site 51
S398
K
L
E
S
A
S
T
S
S
L
E
D
R
V
K
Site 52
S399
L
E
S
A
S
T
S
S
L
E
D
R
V
K
R
Site 53
Y409
D
R
V
K
R
N
I
Y
S
L
Q
R
T
S
V
Site 54
S410
R
V
K
R
N
I
Y
S
L
Q
R
T
S
V
A
Site 55
T414
N
I
Y
S
L
Q
R
T
S
V
A
L
E
K
N
Site 56
S415
I
Y
S
L
Q
R
T
S
V
A
L
E
K
N
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation