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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HIF1AN
Full Name:
Hypoxia-inducible factor 1-alpha inhibitor
Alias:
Factor inhibiting HIF-1;Hypoxia-inducible factor asparagine hydroxylase
Type:
Mass (Da):
40285
Number AA:
349
UniProt ID:
Q9NWT6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Hypoxia-inducible factor 1-alpha inhibitor pan-specific antibody AB-NN248-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN248-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
T
A
A
E
A
V
A
S
G
S
G
E
P
R
E
Site 2
S13
A
E
A
V
A
S
G
S
G
E
P
R
E
E
A
Site 3
S30
L
G
P
A
W
D
E
S
Q
L
R
S
Y
S
F
Site 4
S34
W
D
E
S
Q
L
R
S
Y
S
F
P
T
R
P
Site 5
Y35
D
E
S
Q
L
R
S
Y
S
F
P
T
R
P
I
Site 6
S36
E
S
Q
L
R
S
Y
S
F
P
T
R
P
I
P
Site 7
S46
T
R
P
I
P
R
L
S
Q
S
D
P
R
A
E
Site 8
S48
P
I
P
R
L
S
Q
S
D
P
R
A
E
E
L
Site 9
Y80
A
L
K
W
D
L
E
Y
L
Q
E
N
I
G
N
Site 10
S91
N
I
G
N
G
D
F
S
V
Y
S
A
S
T
H
Site 11
Y93
G
N
G
D
F
S
V
Y
S
A
S
T
H
K
F
Site 12
Y102
A
S
T
H
K
F
L
Y
Y
D
E
K
K
M
A
Site 13
Y103
S
T
H
K
F
L
Y
Y
D
E
K
K
M
A
N
Site 14
S118
F
Q
N
F
K
P
R
S
N
R
E
E
M
K
F
Site 15
Y145
R
G
G
E
E
R
L
Y
L
Q
Q
T
L
N
D
Site 16
T149
E
R
L
Y
L
Q
Q
T
L
N
D
T
V
G
R
Site 17
T153
L
Q
Q
T
L
N
D
T
V
G
R
K
I
V
M
Site 18
T183
K
R
G
W
G
Q
L
T
S
N
L
L
L
I
G
Site 19
T196
I
G
M
E
G
N
V
T
P
A
H
Y
D
E
Q
Site 20
Y200
G
N
V
T
P
A
H
Y
D
E
Q
Q
N
F
F
Site 21
Y228
P
D
Q
F
E
C
L
Y
P
Y
P
V
H
H
P
Site 22
Y249
V
D
F
D
N
P
D
Y
E
R
F
P
N
F
Q
Site 23
T302
F
W
Y
K
G
A
P
T
P
K
R
I
E
Y
P
Site 24
Y308
P
T
P
K
R
I
E
Y
P
L
K
A
H
Q
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation