PhosphoNET

           
Protein Info 
   
Short Name:  RNF12
Full Name:  E3 ubiquitin-protein ligase RLIM
Alias:  LIM domain interacting ring finger; LIM domain interacting ring finger protein; MGC15161; NY-REN-43; Renal carcinoma antigen NY-REN-43; RING finger protein 12; Ring finger protein, LIM domain interacting; Ring zinc finger protein NY-REN-43antigen; RLIM; R-LIM
Type:  EC 6.3.2.-; Transcription, coactivator/corepressor; Ligase; Ubiquitin conjugating system
Mass (Da):  68549
Number AA:  624
UniProt ID:  Q9NVW2
International Prot ID:  IPI00060628
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0017053  GO:0032991  GO:0043234 Uniprot OncoNet
Molecular Function:  GO:0003712  GO:0003714  GO:0003824 PhosphoSite+ KinaseNET
Biological Process:  GO:0006139  GO:0006350  GO:0006355 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MENSDSNDKGSGD
Site 2S11SDSNDKGSGDQSAAQ
Site 3S15DKGSGDQSAAQRRSQ
Site 4S21QSAAQRRSQMDRLDR
Site 5Y33LDREEAFYQFVNNLS
Site 6Y44NNLSEEDYRLMRDNN
Site 7T55RDNNLLGTPGESTEE
Site 8S80EGPPPQNSDENRGGD
Site 9S88DENRGGDSSDDVSNG
Site 10S89ENRGGDSSDDVSNGD
Site 11S93GDSSDDVSNGDSIID
Site 12S97DDVSNGDSIIDWLNS
Site 13S104SIIDWLNSVRQTGNT
Site 14T108WLNSVRQTGNTTRSG
Site 15T111SVRQTGNTTRSGQRG
Site 16S114QTGNTTRSGQRGNQS
Site 17S121SGQRGNQSWRAVSRT
Site 18S126NQSWRAVSRTNPNSG
Site 19T128SWRAVSRTNPNSGDF
Site 20S132VSRTNPNSGDFRFSL
Site 21S138NSGDFRFSLEINVNR
Site 22S149NVNRNNGSQNSENEN
Site 23S159SENENEPSARRSSGE
Site 24S163NEPSARRSSGENVEN
Site 25S164EPSARRSSGENVENN
Site 26S172GENVENNSQRQVENP
Site 27S181RQVENPRSESTSARP
Site 28S183VENPRSESTSARPSR
Site 29T184ENPRSESTSARPSRS
Site 30S185NPRSESTSARPSRSE
Site 31S189ESTSARPSRSERNST
Site 32S191TSARPSRSERNSTEA
Site 33S195PSRSERNSTEALTEV
Site 34T196SRSERNSTEALTEVP
Site 35T200RNSTEALTEVPPTRG
Site 36T205ALTEVPPTRGQRRAR
Site 37S213RGQRRARSRSPDHRR
Site 38S215QRRARSRSPDHRRTR
Site 39T221RSPDHRRTRARAERS
Site 40S228TRARAERSRSPLHPM
Site 41S230ARAERSRSPLHPMSE
Site 42S236RSPLHPMSEIPRRSH
Site 43S242MSEIPRRSHHSISSQ
Site 44S245IPRRSHHSISSQTFE
Site 45S247RRSHHSISSQTFEHP
Site 46S248RSHHSISSQTFEHPL
Site 47S262LVNETEGSSRTRHHV
Site 48T270SRTRHHVTLRQQISG
Site 49S276VTLRQQISGPELLSR
Site 50S289SRGLFAASGTRNASQ
Site 51S295ASGTRNASQGAGSSD
Site 52S301ASQGAGSSDTAASGE
Site 53T303QGAGSSDTAASGEST
Site 54S306GSSDTAASGESTGSG
Site 55T310TAASGESTGSGQRPP
Site 56S312ASGESTGSGQRPPTI
Site 57T318GSGQRPPTIVLDLQV
Site 58S338GEYRQRDSIASRTRS
Site 59S341RQRDSIASRTRSRSQ
Site 60T343RDSIASRTRSRSQTP
Site 61S345SIASRTRSRSQTPNN
Site 62S347ASRTRSRSQTPNNTV
Site 63T349RTRSRSQTPNNTVTY
Site 64T353RSQTPNNTVTYESER
Site 65Y356TPNNTVTYESERGGF
Site 66S358NNTVTYESERGGFRR
Site 67T366ERGGFRRTFSRSERA
Site 68S368GGFRRTFSRSERAGV
Site 69S370FRRTFSRSERAGVRT
Site 70T377SERAGVRTYVSTIRI
Site 71Y378ERAGVRTYVSTIRIP
Site 72T381GVRTYVSTIRIPIRR
Site 73T392PIRRILNTGLSETTS
Site 74Y418TGFGELSYFMYSDSD
Site 75Y421GELSYFMYSDSDSEP
Site 76S422ELSYFMYSDSDSEPT
Site 77S424SYFMYSDSDSEPTGS
Site 78S426FMYSDSDSEPTGSVS
Site 79T429SDSDSEPTGSVSNRN
Site 80S431SDSEPTGSVSNRNME
Site 81S433SEPTGSVSNRNMERA
Site 82S442RNMERAESRSGRGGS
Site 83S444MERAESRSGRGGSGG
Site 84S449SRSGRGGSGGGSSSG
Site 85S453RGGSGGGSSSGSSSS
Site 86S454GGSGGGSSSGSSSSS
Site 87S455GSGGGSSSGSSSSSS
Site 88S457GGGSSSGSSSSSSSS
Site 89S458GGSSSGSSSSSSSSS
Site 90S459GSSSGSSSSSSSSSS
Site 91S460SSSGSSSSSSSSSSS
Site 92S461SSGSSSSSSSSSSSS
Site 93S462SGSSSSSSSSSSSSS
Site 94S463GSSSSSSSSSSSSSS
Site 95S464SSSSSSSSSSSSSSS
Site 96S470SSSSSSSSSSSSSSP
Site 97S471SSSSSSSSSSSSSPS
Site 98S472SSSSSSSSSSSSPSS
Site 99S473SSSSSSSSSSSPSSS
Site 100S474SSSSSSSSSSPSSSS
Site 101S475SSSSSSSSSPSSSSG
Site 102S476SSSSSSSSPSSSSGG
Site 103S478SSSSSSPSSSSGGES
Site 104S479SSSSSPSSSSGGESS
Site 105S480SSSSPSSSSGGESSE
Site 106S481SSSPSSSSGGESSET
Site 107S485SSSSGGESSETSSDL
Site 108S486SSSGGESSETSSDLF
Site 109T488SGGESSETSSDLFEG
Site 110S489GGESSETSSDLFEGS
Site 111S490GESSETSSDLFEGSN
Site 112S496SSDLFEGSNEGSSSS
Site 113S500FEGSNEGSSSSGSSG
Site 114S501EGSNEGSSSSGSSGA
Site 115S502GSNEGSSSSGSSGAR
Site 116S503SNEGSSSSGSSGARR
Site 117S505EGSSSSGSSGARREG
Site 118S506GSSSSGSSGARREGR
Site 119T519GRHRAPVTFDESGSL
Site 120T549DDQPRGLTKEQIDNL
Site 121S560IDNLAMRSFGENDAL
Site 122T569GENDALKTCSVCITE
Site 123T575KTCSVCITEYTEGNK
Site 124T606RWLSENSTCPICRRA
Site 125S617CRRAVLASGNRESVV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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