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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GNL3L
Full Name:
Guanine nucleotide-binding protein-like 3-like protein
Alias:
FLJ10613; Guanine nucleotide binding protein-like 3 (nucleolar)-like
Type:
Mass (Da):
65570
Number AA:
582
UniProt ID:
Q9NVN8
International Prot ID:
IPI00005132
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0005488
GO:0005525
PhosphoSite+
KinaseNET
Biological Process:
GO:0042254
GO:0009987
GO:0016043
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y25
H
K
K
I
S
W
P
Y
P
Q
P
A
K
Q
N
Site 2
T37
K
Q
N
G
K
K
A
T
S
K
V
P
S
A
P
Site 3
S38
Q
N
G
K
K
A
T
S
K
V
P
S
A
P
H
Site 4
S42
K
A
T
S
K
V
P
S
A
P
H
F
V
H
P
Site 5
T84
Q
E
R
Q
K
R
R
T
I
E
S
Y
C
Q
D
Site 6
S87
Q
K
R
R
T
I
E
S
Y
C
Q
D
V
L
R
Site 7
Y88
K
R
R
T
I
E
S
Y
C
Q
D
V
L
R
R
Site 8
Y124
D
E
A
T
R
K
A
Y
Y
K
E
F
R
K
V
Site 9
Y189
V
V
E
K
W
L
D
Y
L
R
N
E
L
P
T
Site 10
T196
Y
L
R
N
E
L
P
T
V
A
F
K
A
S
T
Site 11
S214
V
K
N
L
N
R
C
S
V
P
V
D
Q
A
S
Site 12
S221
S
V
P
V
D
Q
A
S
E
S
L
L
K
S
K
Site 13
S223
P
V
D
Q
A
S
E
S
L
L
K
S
K
A
C
Site 14
S227
A
S
E
S
L
L
K
S
K
A
C
F
G
A
E
Site 15
S266
G
L
P
N
V
G
K
S
S
L
I
N
S
L
K
Site 16
S267
L
P
N
V
G
K
S
S
L
I
N
S
L
K
R
Site 17
S271
G
K
S
S
L
I
N
S
L
K
R
S
R
A
C
Site 18
Y294
T
K
F
M
Q
E
V
Y
L
D
K
F
I
R
L
Site 19
T317
G
P
N
S
E
V
G
T
I
L
R
N
C
V
H
Site 20
T333
Q
K
L
A
D
P
V
T
P
V
E
T
I
L
Q
Site 21
S348
R
C
N
L
E
E
I
S
N
Y
Y
G
V
S
G
Site 22
Y350
N
L
E
E
I
S
N
Y
Y
G
V
S
G
F
Q
Site 23
Y351
L
E
E
I
S
N
Y
Y
G
V
S
G
F
Q
T
Site 24
T358
Y
G
V
S
G
F
Q
T
T
E
H
F
L
T
A
Site 25
T364
Q
T
T
E
H
F
L
T
A
V
A
H
R
L
G
Site 26
S380
K
K
K
G
G
L
Y
S
Q
E
Q
A
A
K
A
Site 27
S398
D
W
V
S
G
K
I
S
F
Y
I
P
P
P
A
Site 28
Y400
V
S
G
K
I
S
F
Y
I
P
P
P
A
T
H
Site 29
T406
F
Y
I
P
P
P
A
T
H
T
L
P
T
H
L
Site 30
T408
I
P
P
P
A
T
H
T
L
P
T
H
L
S
A
Site 31
S414
H
T
L
P
T
H
L
S
A
E
I
V
K
E
M
Site 32
T443
D
T
M
E
C
L
A
T
G
E
S
D
E
L
L
Site 33
S446
E
C
L
A
T
G
E
S
D
E
L
L
G
D
T
Site 34
T453
S
D
E
L
L
G
D
T
D
P
L
E
M
E
I
Site 35
S465
M
E
I
K
L
L
H
S
P
M
T
K
I
A
D
Site 36
T479
D
A
I
E
N
K
T
T
V
Y
K
I
G
D
L
Site 37
T487
V
Y
K
I
G
D
L
T
G
Y
C
T
N
P
N
Site 38
Y489
K
I
G
D
L
T
G
Y
C
T
N
P
N
R
H
Site 39
S511
N
V
D
H
R
P
K
S
N
S
M
V
D
V
C
Site 40
S513
D
H
R
P
K
S
N
S
M
V
D
V
C
S
V
Site 41
S524
V
C
S
V
D
R
R
S
V
L
Q
R
I
M
E
Site 42
S560
K
R
A
D
K
I
A
S
K
L
S
D
S
M
M
Site 43
S563
D
K
I
A
S
K
L
S
D
S
M
M
S
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation