PhosphoNET

           
Protein Info 
   
Short Name:  MDN1
Full Name:  Midasin
Alias:  KIAA0301; MDN1, midasin; MIDAS-containing protein
Type:  Adapter/scaffold protein
Mass (Da):  632820
Number AA:  5596
UniProt ID:  Q9NU22
International Prot ID:  IPI00167941
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:  GO:0000166  GO:0003824  GO:0005488 PhosphoSite+ KinaseNET
Biological Process:  GO:0006461  GO:0009987  GO:0016043 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S23IAAKNEKSRSELGRF
Site 2S25AKNEKSRSELGRFLA
Site 3T37FLAKQVWTPQDRQCV
Site 4S99ERLCVSMSKLIGNHP
Site 5T119ALRYFKDTSPVFQRL
Site 6S120LRYFKDTSPVFQRLF
Site 7S130FQRLFLESSDANPVR
Site 8S131QRLFLESSDANPVRY
Site 9Y138SDANPVRYGRRRMKL
Site 10S161KFLQQEQSVFRELWD
Site 11T181PLLRSHDTLVRWYTA
Site 12Y186HDTLVRWYTANCLAL
Site 13S204MNEEHKLSFLKKIFN
Site 14S212FLKKIFNSDELIHFR
Site 15S243VLANPEVSLWRKQKE
Site 16Y253RKQKELQYLQGHLVS
Site 17S260YLQGHLVSSDLSPRV
Site 18S290GELGGNRSSSREQEL
Site 19S291ELGGNRSSSREQELA
Site 20S292LGGNRSSSREQELAL
Site 21S307RSYVLVESVCKSLQT
Site 22S321TLAMAVASQNAVLLE
Site 23T363KVQLGDQTDSKMLLG
Site 24S365QLGDQTDSKMLLGMY
Site 25Y372SKMLLGMYRCTDVPG
Site 26T389VWQPGTLTQAATMGH
Site 27S448FATRRLLSCGGNWYR
Site 28Y454LSCGGNWYRPLNSHA
Site 29S459NWYRPLNSHATLLDK
Site 30T462RPLNSHATLLDKYWT
Site 31Y467HATLLDKYWTKIHLD
Site 32S487ELNEVLQSRYPSLLA
Site 33T507LDIYIQLTGEKHHSW
Site 34S513LTGEKHHSWSDSSVG
Site 35S515GEKHHSWSDSSVGCE
Site 36S517KHHSWSDSSVGCEQA
Site 37S518HHSWSDSSVGCEQAP
Site 38T539RRENKRPTLEGRELS
Site 39S546TLEGRELSLRDLLNW
Site 40S560WCNRIAHSFDSSSLS
Site 41S563RIAHSFDSSSLSASL
Site 42S564IAHSFDSSSLSASLN
Site 43S565AHSFDSSSLSASLNI
Site 44S567SFDSSSLSASLNIFQ
Site 45S569DSSSLSASLNIFQEA
Site 46T581QEALDCFTAMLSEHT
Site 47S585DCFTAMLSEHTSKLK
Site 48S589AMLSEHTSKLKMAEV
Site 49S599KMAEVIGSKLNISRK
Site 50S604IGSKLNISRKKAEFF
Site 51S638VRLLRKQSEAVHLQR
Site 52Y689GKTSTIQYLAHITGH
Site 53T709NMNQQSDTADLLGGY
Site 54T739FEELFAQTFSKKQNF
Site 55T747FSKKQNFTFLGHIQT
Site 56S774LMQHVHKSAVNKDGK
Site 57S783VNKDGKDSETGLLIK
Site 58T868VLLDRGDTEPLVRHP
Site 59T887FACMNPATDVGKRNL
Site 60T903PGIRNRFTELYVEEL
Site 61Y906RNRFTELYVEELESK
Site 62T942QGIINFYTALRKESG
Site 63S948YTALRKESGTKLVDG
Site 64T950ALRKESGTKLVDGTG
Site 65T956GTKLVDGTGHRPHYS
Site 66Y962GTGHRPHYSLRTLCR
Site 67S963TGHRPHYSLRTLCRA
Site 68T966RPHYSLRTLCRALRF
Site 69S976RALRFAASNPCGNIQ
Site 70S1002LTQLDRASHPIVQKL
Site 71T1055KEPTIDETYILTSSV
Site 72Y1056EPTIDETYILTSSVK
Site 73S1061ETYILTSSVKLNLRD
Site 74Y1119EHTDIQEYIGCYTSD
Site 75Y1123IQEYIGCYTSDSSGK
Site 76T1124QEYIGCYTSDSSGKL
Site 77S1125EYIGCYTSDSSGKLV
Site 78S1127IGCYTSDSSGKLVFK
Site 79Y1146IDAMRKGYWIILDEL
Site 80T1177DNRELLVTETQEVVK
Site 81T1194PRFMLFATQNPPGLY
Site 82S1208YGGRKVLSRAFRNRF
Site 83S1226HFDELPSSELETILH
Site 84T1230LPSSELETILHKRCS
Site 85S1237TILHKRCSLPPSYCS
Site 86S1241KRCSLPPSYCSKLVK
Site 87Y1242RCSLPPSYCSKLVKV
Site 88S1255KVMLDLQSYRRSSSV
Site 89Y1256VMLDLQSYRRSSSVF
Site 90S1259DLQSYRRSSSVFAGK
Site 91S1260LQSYRRSSSVFAGKQ
Site 92S1261QSYRRSSSVFAGKQG
Site 93T1271AGKQGFITLRDLFRW
Site 94Y1282LFRWAERYRLAEPTE
Site 95T1288RYRLAEPTEKEYDWL
Site 96Y1292AEPTEKEYDWLQHLA
Site 97Y1303QHLANDGYMLLAGRV
Site 98S1335KKKLCPQSLFSKENV
Site 99S1354GKLSTQISTLECNFG
Site 100T1444NDKEEIDTSRLFEWH
Site 101S1445DKEEIDTSRLFEWHD
Site 102S1476EISLADDSVLERLNS
Site 103S1483SVLERLNSVLEVEKS
Site 104S1498LVLAEKGSPEDKDSE
Site 105S1504GSPEDKDSEIELLTA
Site 106T1520KKFRILATMNPGGDF
Site 107S1533DFGKKELSPALRNRF
Site 108T1541PALRNRFTEIWCPQS
Site 109S1548TEIWCPQSTSREDLI
Site 110T1549EIWCPQSTSREDLIQ
Site 111S1559EDLIQIISHNLRPGL
Site 112S1576GRIDPKGSDIPEVML
Site 113S1607VSIRDILSWVNFMNK
Site 114T1679LAKIVRLTEYQKNEL
Site 115Y1681KIVRLTEYQKNELKI
Site 116Y1689QKNELKIYDRMKAKE
Site 117Y1725HRNNIADYALSAGTT
Site 118T1743AQRLLRATKLKKPIL
Site 119S1754KPILLEGSPGVGKTS
Site 120T1786LSEQTDITDLFGADL
Site 121Y1847FDHRGEIYVPELGMS
Site 122S1854YVPELGMSFQVQHEK
Site 123S1883GRKGLPRSFLNRFTQ
Site 124S1963QLMLVDQSPGCYDPG
Site 125Y1967VDQSPGCYDPGQHVF
Site 126T1983VYGERMRTEEDKKKV
Site 127S2002KDVFGSNSNPYMGTR
Site 128Y2005FGSNSNPYMGTRLFR
Site 129T2014GTRLFRITPYDVQLG
Site 130Y2016RLFRITPYDVQLGYS
Site 131Y2022PYDVQLGYSVLSRGS
Site 132S2023YDVQLGYSVLSRGSC
Site 133S2026QLGYSVLSRGSCVPH
Site 134S2029YSVLSRGSCVPHPSR
Site 135T2099MNSAMDTTELLGGFE
Site 136Y2154WSHFLLTYKPKCLGE
Site 137T2167GEGGKAITMEIVNKL
Site 138S2205KLVEEFRSFGVKLTQ
Site 139T2211RSFGVKLTQLASGHS
Site 140S2215VKLTQLASGHSHGTF
Site 141S2218TQLASGHSHGTFEWV
Site 142T2221ASGHSHGTFEWVDSM
Site 143S2250NVNFCNPSVLDRLNA
Site 144T2266LEPGGVLTISERGMI
Site 145S2276ERGMIDGSTPTITPN
Site 146T2277RGMIDGSTPTITPNP
Site 147T2279MIDGSTPTITPNPNF
Site 148T2281DGSTPTITPNPNFRL
Site 149S2291PNFRLFLSMDPVHGD
Site 150Y2311RNRGLEIYISGEGDA
Site 151S2313RGLEIYISGEGDAST
Site 152S2319ISGEGDASTPDNLDL
Site 153T2320SGEGDASTPDNLDLK
Site 154S2353ALHTETRSTVVGSPT
Site 155T2354LHTETRSTVVGSPTS
Site 156S2358TRSTVVGSPTSSVST
Site 157S2382QYLQRGLSLDRAFSE
Site 158S2388LSLDRAFSEACWEVY
Site 159Y2395SEACWEVYVCSQHSP
Site 160S2401VYVCSQHSPANRKLV
Site 161S2417ALLEKHVSSLRAHET
Site 162S2418LLEKHVSSLRAHETW
Site 163T2424SSLRAHETWGDSILG
Site 164S2452ATEDSHLSTVRRDGQ
Site 165T2453TEDSHLSTVRRDGQI
Site 166Y2463RDGQILVYCLNRMSM
Site 167T2472LNRMSMKTSSWTRSQ
Site 168S2473NRMSMKTSSWTRSQP
Site 169S2474RMSMKTSSWTRSQPF
Site 170S2478KTSSWTRSQPFTLQD
Site 171T2482WTRSQPFTLQDLEKI
Site 172S2492DLEKIMQSPSPENLK
Site 173S2494EKIMQSPSPENLKFN
Site 174Y2508NAVEVNTYWIDEPDV
Site 175T2528KLLIERATNQDWMLR
Site 176S2563HLEASAASLRNFYSH
Site 177Y2568AASLRNFYSHSLSGA
Site 178S2569ASLRNFYSHSLSGAV
Site 179S2571LRNFYSHSLSGAVSN
Site 180T2617LMDFDPQTDQPDQLF
Site 181Y2637AANKTIIYLDREKRV
Site 182T2646DREKRVFTEANLVSV
Site 183S2652FTEANLVSVGSKKLR
Site 184S2661GSKKLRESVLRMSFE
Site 185S2666RESVLRMSFEFHQDP
Site 186S2675EFHQDPESYHTLPHE
Site 187T2678QDPESYHTLPHEIVV
Site 188S2710QSSQGMVSDASANEI
Site 189S2713QGMVSDASANEILGS
Site 190S2720SANEILGSLRWRDRF
Site 191T2729RWRDRFWTVADTVKV
Site 192T2733RFWTVADTVKVDAPG
Site 193Y2766IPRLLMNYEDKYYKE
Site 194Y2770LMNYEDKYYKEVQTV
Site 195Y2771MNYEDKYYKEVQTVS
Site 196S2787HIQNCLGSQTGGFAG
Site 197S2834LAIREQMSALGESGW
Site 198S2853NRLQVVASQWTLKKS
Site 199T2856QVVASQWTLKKSLLQ
Site 200S2860SQWTLKKSLLQAWGL
Site 201S2878ANILEDVSLDELKNF
Site 202S2912KKHDEASSLSHPDLT
Site 203S2914HDEASSLSHPDLTSV
Site 204T2919SLSHPDLTSVIHLTR
Site 205S2920LSHPDLTSVIHLTRS
Site 206S2959QACLRRCSKNQQPQI
Site 207T2984CLYHTPVTPQELRDL
Site 208S2993QELRDLWSLLHHQKV
Site 209S3001LLHHQKVSPEEITSL
Site 210S3007VSPEEITSLWSELFN
Site 211T3024FMSFWSSTVTTNPEY
Site 212T3026SFWSSTVTTNPEYWL
Site 213S3049QQREAPKSVLDSTLK
Site 214S3053APKSVLDSTLKGPGN
Site 215T3054PKSVLDSTLKGPGNL
Site 216T3075KCCFEVLTSSWRASP
Site 217S3081LTSSWRASPWDVSGL
Site 218S3086RASPWDVSGLPILSS
Site 219T3097ILSSSHVTLGEWVER
Site 220S3112TQQLQDISSMLWTNM
Site 221S3113QQLQDISSMLWTNMA
Site 222T3130SVAEFRRTDSQLQGQ
Site 223S3132AEFRRTDSQLQGQVL
Site 224S3153LAELLPESRRQEYMQ
Site 225Y3158PESRRQEYMQNCEQL
Site 226S3170EQLLLGSSQAFQHVG
Site 227S3210HFVGEGESKRSLPEP
Site 228S3213GEGESKRSLPEPAQR
Site 229S3222PEPAQRGSLWVSLGL
Site 230Y3249DPAVKREYKLNYVKE
Site 231Y3253KREYKLNYVKEELHQ
Site 232T3267QLQCEWKTRNLSSQL
Site 233S3271EWKTRNLSSQLQTGR
Site 234S3272WKTRNLSSQLQTGRD
Site 235T3276NLSSQLQTGRDLEDE
Site 236S3287LEDEVVVSYSHPHVR
Site 237Y3288EDEVVVSYSHPHVRL
Site 238S3289DEVVVSYSHPHVRLL
Site 239T3307MDRLDNLTCHLLKKQ
Site 240Y3323FRPQLPAYESLVQEI
Site 241S3325PQLPAYESLVQEIHH
Site 242S3361LHIDGPRSAQVAQSL
Site 243S3367RSAQVAQSLLKEEAS
Site 244S3374SLLKEEASWQQSHHQ
Site 245S3387HQFRKRLSEEYTFYP
Site 246Y3390RKRLSEEYTFYPDAV
Site 247T3391KRLSEEYTFYPDAVS
Site 248Y3393LSEEYTFYPDAVSPL
Site 249S3416HGMRLVASELHTSLH
Site 250S3425LHTSLHSSMVGADRL
Site 251T3434VGADRLGTLATALLA
Site 252S3444TALLAFPSVGPTFPT
Site 253T3448AFPSVGPTFPTYYAH
Site 254Y3452VGPTFPTYYAHADTL
Site 255Y3453GPTFPTYYAHADTLC
Site 256T3458TYYAHADTLCSVKSE
Site 257S3464DTLCSVKSEEVLRGL
Site 258S3479GKLILKRSGGKELEG
Site 259T3494KGQKACPTREQLLMN
Site 260Y3553AEQESGLYRYRSRNS
Site 261Y3555QESGLYRYRSRNSRT
Site 262S3557SGLYRYRSRNSRTAL
Site 263S3560YRYRSRNSRTALSEE
Site 264S3565RNSRTALSEEEEEER
Site 265T3610GQEEEAGTNPALLSQ
Site 266S3616GTNPALLSQNSMQAV
Site 267T3643RSLWYQQTLPPHEAK
Site 268Y3652PPHEAKHYLSLFLSC
Site 269Y3713MVKPDGPYDFYQHPN
Site 270Y3716PDGPYDFYQHPNVPE
Site 271S3739QGFSEAVSHLLQDWP
Site 272S3767RIRSFPLSSPISKFL
Site 273S3768IRSFPLSSPISKFLN
Site 274S3792QDWEENASRALSLRK
Site 275S3796ENASRALSLRKHLDL
Site 276T3831DNTMKRHTEKSTKHW
Site 277T3835KRHTEKSTKHWFSIY
Site 278S3879QAFIEGSSLGEFHVR
Site 279S3908PQVEGKDSLCSVLWN
Site 280S3936AKIVELRSPLEKELK
Site 281S3962SFWSIKQSVEKTHRT
Site 282T3966IKQSVEKTHRTLFKF
Site 283T3969SVEKTHRTLFKFMKK
Site 284S3982KKFEAVLSEPCRSSL
Site 285S3987VLSEPCRSSLVESDK
Site 286S3988LSEPCRSSLVESDKE
Site 287S3992CRSSLVESDKEEQPD
Site 288T4005PDFLPRPTDGAASEL
Site 289S4010RPTDGAASELSSIQN
Site 290S4014GAASELSSIQNLNRA
Site 291T4070RMRKMCLTFMKESPL
Site 292S4075CLTFMKESPLPRLVE
Site 293S4093QFTGEVISSVSELQS
Site 294S4100SSVSELQSLKVEPSA
Site 295S4106QSLKVEPSAEKEKQR
Site 296S4128MQKQRALSDLFKHLA
Site 297S4140HLAKIGLSYRKGLAW
Site 298S4150KGLAWARSKNPQEML
Site 299S4173SALSIVSSTQEADSR
Site 300S4179SSTQEADSRLLTEIS
Site 301T4183EADSRLLTEISSSWD
Site 302S4186SRLLTEISSSWDGCQ
Site 303S4187RLLTEISSSWDGCQK
Site 304S4188LLTEISSSWDGCQKY
Site 305Y4195SWDGCQKYFYRSLAR
Site 306Y4197DGCQKYFYRSLARHA
Site 307T4212RLNAALATPAKEMGM
Site 308S4242MLVRQRRSLTTLSEQ
Site 309T4244VRQRRSLTTLSEQWI
Site 310T4245RQRRSLTTLSEQWII
Site 311S4247RRSLTTLSEQWIILR
Site 312S4258IILRNLLSCVQEIHS
Site 313Y4273RLMGPQAYPVAFPPQ
Site 314S4357DLIPSNLSYPSPIPG
Site 315Y4358LIPSNLSYPSPIPGS
Site 316S4360PSNLSYPSPIPGSQL
Site 317S4365YPSPIPGSQLPSGCR
Site 318S4369IPGSQLPSGCRMRKQ
Site 319T4384DHLWQQSTTRLTEML
Site 320T4388QQSTTRLTEMLKTIK
Site 321T4393RLTEMLKTIKTVKAD
Site 322T4396EMLKTIKTVKADVDK
Site 323S4408VDKIRQQSCETLFHS
Site 324S4455MEVEQRDSQMALVES
Site 325Y4465ALVESLEYVRGEISK
Site 326T4478SKAMADFTTWKTHLL
Site 327T4482ADFTTWKTHLLTSDS
Site 328S4487WKTHLLTSDSQGGNQ
Site 329S4489THLLTSDSQGGNQML
Site 330S4505EGFVEDFSEQMEIAI
Site 331S4538EENTDQASPQEDYAG
Site 332Y4543QASPQEDYAGFERLQ
Site 333S4551AGFERLQSGHLTKLL
Site 334T4555RLQSGHLTKLLEDDF
Site 335S4587ELLERLKSYGEDGTA
Site 336T4593KSYGEDGTAAKHLFF
Site 337S4615VRLVPVLSSYSDLVL
Site 338Y4617LVPVLSSYSDLVLFF
Site 339S4618VPVLSSYSDLVLFFL
Site 340S4664PKEFMEDSAGEGATE
Site 341Y4675GATEFHDYEGGGIGE
Site 342S4690GEGMKDVSDQIGNEE
Site 343T4702NEEQVEDTFQKGQEK
Site 344S4716KDKEDPDSKSDIKGE
Site 345S4718KEDPDSKSDIKGEDN
Site 346S4752QEEDDEKSDSEGGDL
Site 347S4754EDDEKSDSEGGDLDK
Site 348T4795EEEEDNKTEETGPGM
Site 349S4807PGMDEEDSELVAKDD
Site 350S4818AKDDNLDSGNSNKDK
Site 351S4821DNLDSGNSNKDKSQQ
Site 352S4826GNSNKDKSQQDKKEE
Site 353Y4858EQIDERDYDENEVDP
Site 354Y4866DENEVDPYHGNQEKV
Site 355S4889PDDLNLDSEDKNGGE
Site 356T4898DKNGGEDTDNEEGEE
Site 357T4928EAEERGETETDQNES
Site 358T4930EERGETETDQNESQS
Site 359S4935TETDQNESQSPQEPE
Site 360S4937TDQNESQSPQEPEEG
Site 361S4946QEPEEGPSEDDKAEG
Site 362T4959EGEEEMDTGADDQDG
Site 363S4982HSEEQQQSVEEKDKE
Site 364S5015EEEEREDSDTEEQVP
Site 365T5017EEREDSDTEEQVPEA
Site 366S5032LERKEHASCGQTGVE
Site 367S5065QGKEEHGSGAADANQ
Site 368S5078NQAEGHESNFIAQLA
Site 369T5094QKHTRKNTQSFKRKP
Site 370S5096HTRKNTQSFKRKPGQ
Site 371T5123RVHKRLRTVDTDSHA
Site 372T5126KRLRTVDTDSHAEQG
Site 373S5128LRTVDTDSHAEQGPA
Site 374Y5158IKQGSDAYDAQTYDV
Site 375T5162SDAYDAQTYDVASKE
Site 376Y5163DAYDAQTYDVASKEQ
Site 377S5167AQTYDVASKEQQQSA
Site 378S5173ASKEQQQSAKDSGKD
Site 379S5177QQQSAKDSGKDQEEE
Site 380T5189EEEEIEDTLMDTEEQ
Site 381T5193IEDTLMDTEEQEEFK
Site 382S5214LKPEEIKSGTTAPLG
Site 383T5216PEEIKSGTTAPLGFD
Site 384T5242EEDQDPRTDKAHKET
Site 385S5260KPERSRESTIHTAHQ
Site 386T5261PERSRESTIHTAHQF
Site 387T5264SRESTIHTAHQFLMD
Site 388S5300EMWQPRESGNPEEEK
Site 389Y5347AAKLKGDYRTGKRLN
Site 390T5349KLKGDYRTGKRLNIR
Site 391Y5361NIRKVIPYIASQFRK
Site 392S5364KVIPYIASQFRKDKI
Site 393T5376DKIWLRRTKPSKRQY
Site 394Y5383TKPSKRQYQICLAID
Site 395S5393CLAIDDSSSMVDNHT
Site 396S5394LAIDDSSSMVDNHTK
Site 397Y5445FHEQFSDYSGSQILR
Site 398S5446HEQFSDYSGSQILRL
Site 399S5448QFSDYSGSQILRLCK
Site 400S5481FAAAQQLSQNISSET
Site 401S5485QQLSQNISSETAQLL
Site 402S5486QLSQNISSETAQLLL
Site 403S5532FVVLDNPSSRDSILD
Site 404S5533VVLDNPSSRDSILDI
Site 405S5536DNPSSRDSILDIKVP
Site 406S5556GEMPEIRSYMEEFPF
Site 407Y5557EMPEIRSYMEEFPFP
Site 408Y5566EEFPFPYYIILRDVN
Site 409T5578DVNALPETLSDALRQ
Site 410S5580NALPETLSDALRQWF
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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