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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RNF146
Full Name:
RING finger protein 146
Alias:
Dactylidin; DJ351K20.1; DKFZp434O1427; RN146
Type:
Unknown function
Mass (Da):
38950
Number AA:
359
UniProt ID:
Q9NTX7
International Prot ID:
IPI00008911
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
T
N
R
K
A
N
E
S
C
S
N
T
A
P
S
Site 2
S26
R
K
A
N
E
S
C
S
N
T
A
P
S
L
T
Site 3
T28
A
N
E
S
C
S
N
T
A
P
S
L
T
V
P
Site 4
S31
S
C
S
N
T
A
P
S
L
T
V
P
E
C
A
Site 5
S90
L
D
K
P
T
L
L
S
P
E
E
L
K
A
A
Site 6
Y104
A
S
R
G
N
G
E
Y
A
W
Y
Y
E
G
R
Site 7
Y107
G
N
G
E
Y
A
W
Y
Y
E
G
R
N
G
W
Site 8
Y117
G
R
N
G
W
W
Q
Y
D
E
R
T
S
R
E
Site 9
S122
W
Q
Y
D
E
R
T
S
R
E
L
E
D
A
F
Site 10
S130
R
E
L
E
D
A
F
S
K
G
K
K
N
T
E
Site 11
Y155
D
L
E
N
M
V
Q
Y
R
R
N
E
H
G
R
Site 12
T189
R
L
D
C
D
A
N
T
V
N
L
A
R
E
S
Site 13
S196
T
V
N
L
A
R
E
S
S
A
D
G
A
D
S
Site 14
S197
V
N
L
A
R
E
S
S
A
D
G
A
D
S
V
Site 15
S203
S
S
A
D
G
A
D
S
V
S
A
Q
S
G
A
Site 16
S205
A
D
G
A
D
S
V
S
A
Q
S
G
A
S
V
Site 17
T223
V
S
S
V
R
P
L
T
S
V
D
G
Q
L
T
Site 18
S224
S
S
V
R
P
L
T
S
V
D
G
Q
L
T
S
Site 19
T230
T
S
V
D
G
Q
L
T
S
P
A
T
P
S
P
Site 20
S231
S
V
D
G
Q
L
T
S
P
A
T
P
S
P
D
Site 21
T234
G
Q
L
T
S
P
A
T
P
S
P
D
A
S
T
Site 22
S236
L
T
S
P
A
T
P
S
P
D
A
S
T
S
L
Site 23
S240
A
T
P
S
P
D
A
S
T
S
L
E
D
S
F
Site 24
S242
P
S
P
D
A
S
T
S
L
E
D
S
F
A
H
Site 25
S246
A
S
T
S
L
E
D
S
F
A
H
L
Q
L
S
Site 26
S253
S
F
A
H
L
Q
L
S
G
D
N
T
A
E
R
Site 27
T257
L
Q
L
S
G
D
N
T
A
E
R
S
H
R
G
Site 28
S261
G
D
N
T
A
E
R
S
H
R
G
E
G
E
E
Site 29
S272
E
G
E
E
D
H
E
S
P
S
S
G
R
V
P
Site 30
S274
E
E
D
H
E
S
P
S
S
G
R
V
P
A
P
Site 31
S275
E
D
H
E
S
P
S
S
G
R
V
P
A
P
D
Site 32
T283
G
R
V
P
A
P
D
T
S
I
E
E
T
E
S
Site 33
S284
R
V
P
A
P
D
T
S
I
E
E
T
E
S
D
Site 34
T288
P
D
T
S
I
E
E
T
E
S
D
A
S
S
D
Site 35
S290
T
S
I
E
E
T
E
S
D
A
S
S
D
S
E
Site 36
S293
E
E
T
E
S
D
A
S
S
D
S
E
D
V
S
Site 37
S294
E
T
E
S
D
A
S
S
D
S
E
D
V
S
A
Site 38
S296
E
S
D
A
S
S
D
S
E
D
V
S
A
V
V
Site 39
S300
S
S
D
S
E
D
V
S
A
V
V
A
Q
H
S
Site 40
T321
L
V
S
N
A
N
Q
T
V
P
D
R
S
D
R
Site 41
S326
N
Q
T
V
P
D
R
S
D
R
S
G
T
D
R
Site 42
S329
V
P
D
R
S
D
R
S
G
T
D
R
S
V
A
Site 43
T331
D
R
S
D
R
S
G
T
D
R
S
V
A
G
G
Site 44
S334
D
R
S
G
T
D
R
S
V
A
G
G
G
T
V
Site 45
S342
V
A
G
G
G
T
V
S
V
S
V
R
S
R
R
Site 46
S344
G
G
G
T
V
S
V
S
V
R
S
R
R
P
D
Site 47
S347
T
V
S
V
S
V
R
S
R
R
P
D
G
Q
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation