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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SACM1L
Full Name:
Phosphatidylinositide phosphatase SAC1
Alias:
Suppressor of actin mutations 1-like protein
Type:
Mass (Da):
66949
Number AA:
587
UniProt ID:
Q9NTJ5
International Prot ID:
IPI00022275
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0005789
GO:0005794
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0016787
GO:0016788
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
E
Q
L
K
L
H
I
T
P
E
K
F
Y
V
E
Site 2
Y19
H
I
T
P
E
K
F
Y
V
E
A
C
D
D
G
Site 3
T32
D
G
A
D
D
V
L
T
I
D
R
V
S
T
E
Site 4
T41
D
R
V
S
T
E
V
T
L
A
V
K
K
D
V
Site 5
S51
V
K
K
D
V
P
P
S
A
V
T
R
P
I
F
Site 6
S99
A
T
D
F
D
V
L
S
Y
K
K
T
M
L
H
Site 7
T103
D
V
L
S
Y
K
K
T
M
L
H
L
T
D
I
Site 8
T117
I
Q
L
Q
D
N
K
T
F
L
A
M
L
N
H
Site 9
T140
F
S
T
T
Y
D
L
T
H
T
L
Q
R
L
S
Site 10
T142
T
T
Y
D
L
T
H
T
L
Q
R
L
S
N
T
Site 11
S147
T
H
T
L
Q
R
L
S
N
T
S
P
E
F
Q
Site 12
S150
L
Q
R
L
S
N
T
S
P
E
F
Q
E
M
S
Site 13
S157
S
P
E
F
Q
E
M
S
L
L
E
R
A
D
Q
Site 14
S177
G
H
L
L
R
E
L
S
A
Q
P
E
V
H
R
Site 15
Y205
S
C
S
I
N
G
K
Y
F
D
W
I
L
I
S
Site 16
Y223
C
F
R
A
G
V
R
Y
Y
V
R
G
I
D
S
Site 17
Y224
F
R
A
G
V
R
Y
Y
V
R
G
I
D
S
E
Site 18
Y246
E
T
E
Q
I
V
H
Y
N
G
S
K
A
S
F
Site 19
S249
Q
I
V
H
Y
N
G
S
K
A
S
F
V
Q
T
Site 20
S252
H
Y
N
G
S
K
A
S
F
V
Q
T
R
G
S
Site 21
S259
S
F
V
Q
T
R
G
S
I
P
V
F
W
S
Q
Site 22
S265
G
S
I
P
V
F
W
S
Q
R
P
N
L
K
Y
Site 23
Y272
S
Q
R
P
N
L
K
Y
K
P
L
P
Q
I
S
Site 24
T320
S
E
K
P
L
E
Q
T
F
A
T
M
V
S
S
Site 25
S353
N
M
R
W
D
R
L
S
I
L
L
D
Q
V
A
Site 26
S367
A
E
M
Q
D
E
L
S
Y
F
L
V
D
S
A
Site 27
Y368
E
M
Q
D
E
L
S
Y
F
L
V
D
S
A
G
Site 28
T396
C
M
D
C
L
D
R
T
N
V
I
Q
S
L
L
Site 29
S407
Q
S
L
L
A
R
R
S
L
Q
A
Q
L
Q
R
Site 30
T457
A
G
T
G
A
L
K
T
D
F
T
R
T
G
K
Site 31
T466
F
T
R
T
G
K
R
T
H
L
G
L
I
M
D
Site 32
S494
S
D
G
F
R
Q
D
S
I
D
L
F
L
G
N
Site 33
Y502
I
D
L
F
L
G
N
Y
S
V
D
E
L
E
S
Site 34
S503
D
L
F
L
G
N
Y
S
V
D
E
L
E
S
H
Site 35
S509
Y
S
V
D
E
L
E
S
H
S
P
L
S
V
P
Site 36
S511
V
D
E
L
E
S
H
S
P
L
S
V
P
R
D
Site 37
S514
L
E
S
H
S
P
L
S
V
P
R
D
W
K
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation