KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ATP8A2
Full Name:
Probable phospholipid-transporting ATPase IB
Alias:
ATPase class I type 8A member 2; ATPase, aminophospholipid transporter-like, class I, type 8A, member 2; ATPIB; FLJ45330; ML-1; Phospholipid-transporting ATPase IB
Type:
Transporter; Cell cycle regulation; EC 3.6.3.1; Hydrolase
Mass (Da):
129242
Number AA:
1148
UniProt ID:
Q9NTI2
International Prot ID:
IPI00465166
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016020
GO:0016021
GO:0031224
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0000287
GO:0003824
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006869
GO:0008285
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
S
R
A
T
S
V
G
D
Q
L
E
Site 2
S6
_
_
M
S
R
A
T
S
V
G
D
Q
L
E
A
Site 3
Y19
E
A
P
A
R
T
I
Y
L
N
Q
P
H
L
N
Site 4
S34
K
F
R
D
N
Q
I
S
T
A
K
Y
S
V
L
Site 5
Y49
T
F
L
P
R
F
L
Y
E
Q
I
R
R
A
A
Site 6
S73
L
Q
Q
I
P
D
V
S
P
T
G
R
Y
T
T
Site 7
T75
Q
I
P
D
V
S
P
T
G
R
Y
T
T
L
V
Site 8
Y161
S
E
P
Q
A
M
C
Y
V
E
T
A
N
L
D
Site 9
T187
S
H
T
A
D
M
Q
T
R
E
V
L
M
K
L
Site 10
Y208
E
G
P
N
R
H
L
Y
D
F
T
G
N
L
N
Site 11
T211
N
R
H
L
Y
D
F
T
G
N
L
N
L
D
G
Site 12
S220
N
L
N
L
D
G
K
S
L
V
A
L
G
P
D
Site 13
T234
D
Q
I
L
L
R
G
T
Q
L
R
N
T
Q
W
Site 14
Y297
V
S
S
A
G
A
L
Y
W
N
R
S
H
G
E
Site 15
Y308
S
H
G
E
K
N
W
Y
I
K
K
M
D
T
T
Site 16
T366
M
Y
Y
I
G
N
D
T
P
A
M
A
R
T
S
Site 17
S373
T
P
A
M
A
R
T
S
N
L
N
E
E
L
G
Site 18
Y384
E
E
L
G
Q
V
K
Y
L
F
S
D
K
T
G
Site 19
T390
K
Y
L
F
S
D
K
T
G
T
L
T
C
N
I
Site 20
T394
S
D
K
T
G
T
L
T
C
N
I
M
N
F
K
Site 21
S421
P
E
L
A
R
E
P
S
S
D
D
F
C
R
M
Site 22
S422
E
L
A
R
E
P
S
S
D
D
F
C
R
M
P
Site 23
T453
N
I
E
D
R
H
P
T
A
P
C
I
Q
E
F
Site 24
Y481
K
D
G
D
N
I
I
Y
Q
A
S
S
P
D
E
Site 25
S531
L
N
V
L
E
F
S
S
D
R
K
R
M
S
V
Site 26
S537
S
S
D
R
K
R
M
S
V
I
V
R
T
P
S
Site 27
T542
R
M
S
V
I
V
R
T
P
S
G
R
L
R
L
Site 28
Y550
P
S
G
R
L
R
L
Y
C
K
G
A
D
N
V
Site 29
S563
N
V
I
F
E
R
L
S
K
D
S
K
Y
M
E
Site 30
S566
F
E
R
L
S
K
D
S
K
Y
M
E
E
T
L
Site 31
Y568
R
L
S
K
D
S
K
Y
M
E
E
T
L
C
H
Site 32
Y578
E
T
L
C
H
L
E
Y
F
A
T
E
G
L
R
Site 33
Y599
A
D
L
S
E
N
E
Y
E
E
W
L
K
V
Y
Site 34
Y606
Y
E
E
W
L
K
V
Y
Q
E
A
S
T
I
L
Site 35
Y624
A
Q
R
L
E
E
C
Y
E
I
I
E
K
N
L
Site 36
T699
K
E
D
S
L
D
A
T
R
A
A
I
T
Q
H
Site 37
Y731
I
D
G
H
T
L
K
Y
A
L
S
F
E
V
R
Site 38
S734
H
T
L
K
Y
A
L
S
F
E
V
R
R
S
F
Site 39
Y812
Q
A
T
N
N
S
D
Y
A
I
A
Q
F
S
Y
Site 40
S894
T
L
G
I
F
E
R
S
C
T
Q
E
S
M
L
Site 41
T896
G
I
F
E
R
S
C
T
Q
E
S
M
L
R
F
Site 42
S899
E
R
S
C
T
Q
E
S
M
L
R
F
P
Q
L
Site 43
Y907
M
L
R
F
P
Q
L
Y
K
I
T
Q
N
G
E
Site 44
T947
M
K
A
L
E
H
D
T
V
L
T
S
G
H
A
Site 45
S951
E
H
D
T
V
L
T
S
G
H
A
T
D
Y
L
Site 46
T1023
P
D
M
R
G
Q
A
T
M
V
L
S
S
A
H
Site 47
T1055
A
W
R
A
A
K
H
T
C
K
K
T
L
L
E
Site 48
S1071
V
Q
E
L
E
T
K
S
R
V
L
G
K
A
V
Site 49
S1082
G
K
A
V
L
R
D
S
N
G
K
R
L
N
E
Site 50
T1101
I
K
R
L
G
R
K
T
P
P
T
L
F
R
G
Site 51
T1104
L
G
R
K
T
P
P
T
L
F
R
G
S
S
L
Site 52
S1109
P
P
T
L
F
R
G
S
S
L
Q
Q
G
V
P
Site 53
S1110
P
T
L
F
R
G
S
S
L
Q
Q
G
V
P
H
Site 54
S1122
V
P
H
G
Y
A
F
S
Q
E
E
H
G
A
V
Site 55
Y1138
Q
E
E
V
I
R
A
Y
D
T
T
K
K
K
S
Site 56
T1140
E
V
I
R
A
Y
D
T
T
K
K
K
S
R
K
Site 57
T1141
V
I
R
A
Y
D
T
T
K
K
K
S
R
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation