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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLC4
Full Name:
Kinesin light chain 4
Alias:
BA387M24.3; Kinesin-like protein 8; KLC8; KNSL8
Type:
Motor protein; Microtubule binding protein
Mass (Da):
68640
Number AA:
619
UniProt ID:
Q9NSK0
International Prot ID:
IPI00398812
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005871
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0003777
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
E
P
A
G
H
R
L
S
Q
E
E
I
L
G
S
Site 2
S25
S
Q
E
E
I
L
G
S
T
R
L
V
S
Q
G
Site 3
S30
L
G
S
T
R
L
V
S
Q
G
L
E
A
L
R
Site 4
S38
Q
G
L
E
A
L
R
S
E
H
Q
A
V
L
Q
Site 5
S46
E
H
Q
A
V
L
Q
S
L
S
Q
T
I
E
C
Site 6
S74
K
A
R
Q
L
R
R
S
M
E
N
I
E
L
G
Site 7
S83
E
N
I
E
L
G
L
S
E
A
Q
V
M
L
A
Site 8
S93
Q
V
M
L
A
L
A
S
H
L
S
T
V
E
S
Site 9
S96
L
A
L
A
S
H
L
S
T
V
E
S
E
K
Q
Site 10
T97
A
L
A
S
H
L
S
T
V
E
S
E
K
Q
K
Site 11
S100
S
H
L
S
T
V
E
S
E
K
Q
K
L
R
A
Site 12
T126
L
R
D
E
L
A
G
T
Q
Q
R
L
Q
R
S
Site 13
Y156
F
L
G
Q
L
R
Q
Y
D
E
D
G
H
T
S
Site 14
T162
Q
Y
D
E
D
G
H
T
S
E
E
K
E
G
D
Site 15
T171
E
E
K
E
G
D
A
T
K
D
S
L
D
D
L
Site 16
S174
E
G
D
A
T
K
D
S
L
D
D
L
F
P
N
Site 17
S188
N
E
E
E
E
D
P
S
N
G
L
S
R
G
Q
Site 18
S192
E
D
P
S
N
G
L
S
R
G
Q
G
A
T
A
Site 19
T198
L
S
R
G
Q
G
A
T
A
A
Q
Q
G
G
Y
Site 20
Y205
T
A
A
Q
Q
G
G
Y
E
I
P
A
R
L
R
Site 21
S245
L
E
D
L
E
R
T
S
G
R
G
H
P
D
V
Site 22
Y269
V
Y
R
D
Q
N
K
Y
K
E
A
A
H
L
L
Site 23
S281
H
L
L
N
D
A
L
S
I
R
E
S
T
L
G
Site 24
S285
D
A
L
S
I
R
E
S
T
L
G
P
D
H
P
Site 25
T286
A
L
S
I
R
E
S
T
L
G
P
D
H
P
A
Site 26
Y305
L
N
N
L
A
V
L
Y
G
K
R
G
K
Y
K
Site 27
Y311
L
Y
G
K
R
G
K
Y
K
E
A
E
P
L
C
Site 28
Y353
L
C
Q
N
Q
G
K
Y
E
A
V
E
R
Y
Y
Site 29
Y359
K
Y
E
A
V
E
R
Y
Y
Q
R
A
L
A
I
Site 30
Y360
Y
E
A
V
E
R
Y
Y
Q
R
A
L
A
I
Y
Site 31
Y367
Y
Q
R
A
L
A
I
Y
E
G
Q
L
G
P
D
Site 32
Y389
K
N
N
L
A
S
C
Y
L
K
Q
G
K
Y
A
Site 33
Y395
C
Y
L
K
Q
G
K
Y
A
E
A
E
T
L
Y
Site 34
S416
A
H
V
Q
E
F
G
S
V
D
D
D
H
K
P
Site 35
S437
E
R
E
E
M
S
K
S
R
H
H
E
G
G
T
Site 36
T444
S
R
H
H
E
G
G
T
P
Y
A
E
Y
G
G
Site 37
Y446
H
H
E
G
G
T
P
Y
A
E
Y
G
G
W
Y
Site 38
Y449
G
G
T
P
Y
A
E
Y
G
G
W
Y
K
A
C
Site 39
Y453
Y
A
E
Y
G
G
W
Y
K
A
C
K
V
S
S
Site 40
S459
W
Y
K
A
C
K
V
S
S
P
T
V
N
T
T
Site 41
S460
Y
K
A
C
K
V
S
S
P
T
V
N
T
T
L
Site 42
T465
V
S
S
P
T
V
N
T
T
L
R
N
L
G
A
Site 43
T466
S
S
P
T
V
N
T
T
L
R
N
L
G
A
L
Site 44
Y474
L
R
N
L
G
A
L
Y
R
R
Q
G
K
L
E
Site 45
T485
G
K
L
E
A
A
E
T
L
E
E
C
A
L
R
Site 46
T498
L
R
S
R
R
Q
G
T
D
P
I
S
Q
T
K
Site 47
S502
R
Q
G
T
D
P
I
S
Q
T
K
V
A
E
L
Site 48
S513
V
A
E
L
L
G
E
S
D
G
R
R
T
S
Q
Site 49
T518
G
E
S
D
G
R
R
T
S
Q
E
G
P
G
D
Site 50
S519
E
S
D
G
R
R
T
S
Q
E
G
P
G
D
S
Site 51
S526
S
Q
E
G
P
G
D
S
V
K
F
E
G
G
E
Site 52
S536
F
E
G
G
E
D
A
S
V
A
V
E
W
S
G
Site 53
S546
V
E
W
S
G
D
G
S
G
T
L
Q
R
S
G
Site 54
T548
W
S
G
D
G
S
G
T
L
Q
R
S
G
S
L
Site 55
S552
G
S
G
T
L
Q
R
S
G
S
L
G
K
I
R
Site 56
S554
G
T
L
Q
R
S
G
S
L
G
K
I
R
D
V
Site 57
S565
I
R
D
V
L
R
R
S
S
E
L
L
V
R
K
Site 58
S566
R
D
V
L
R
R
S
S
E
L
L
V
R
K
L
Site 59
T576
L
V
R
K
L
Q
G
T
E
P
R
P
S
S
S
Site 60
S581
Q
G
T
E
P
R
P
S
S
S
N
M
K
R
A
Site 61
S582
G
T
E
P
R
P
S
S
S
N
M
K
R
A
A
Site 62
S583
T
E
P
R
P
S
S
S
N
M
K
R
A
A
S
Site 63
S590
S
N
M
K
R
A
A
S
L
N
Y
L
N
Q
P
Site 64
Y593
K
R
A
A
S
L
N
Y
L
N
Q
P
S
A
A
Site 65
S598
L
N
Y
L
N
Q
P
S
A
A
P
L
Q
V
S
Site 66
S605
S
A
A
P
L
Q
V
S
R
G
L
S
A
S
T
Site 67
S609
L
Q
V
S
R
G
L
S
A
S
T
M
D
L
S
Site 68
S611
V
S
R
G
L
S
A
S
T
M
D
L
S
S
S
Site 69
T612
S
R
G
L
S
A
S
T
M
D
L
S
S
S
S
Site 70
S616
S
A
S
T
M
D
L
S
S
S
S
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation