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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HOMER2
Full Name:
Homer protein homolog 2
Alias:
Cupidin
Type:
Mass (Da):
40627
Number AA:
354
UniProt ID:
Q9NSB8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
K
K
N
W
M
P
A
S
K
Q
A
V
T
V
S
Site 2
T33
P
A
S
K
Q
A
V
T
V
S
Y
F
Y
D
V
Site 3
S35
S
K
Q
A
V
T
V
S
Y
F
Y
D
V
T
R
Site 4
Y36
K
Q
A
V
T
V
S
Y
F
Y
D
V
T
R
N
Site 5
Y45
Y
D
V
T
R
N
S
Y
R
I
I
S
V
D
G
Site 6
S49
R
N
S
Y
R
I
I
S
V
D
G
A
K
V
I
Site 7
T66
S
T
I
T
P
N
M
T
F
T
K
T
S
Q
K
Site 8
S80
K
F
G
Q
W
A
D
S
R
A
N
T
V
F
G
Site 9
T84
W
A
D
S
R
A
N
T
V
F
G
L
G
F
S
Site 10
T117
A
K
I
A
K
D
K
T
Q
E
K
I
E
T
S
Site 11
T123
K
T
Q
E
K
I
E
T
S
S
N
H
S
Q
E
Site 12
S124
T
Q
E
K
I
E
T
S
S
N
H
S
Q
E
S
Site 13
S125
Q
E
K
I
E
T
S
S
N
H
S
Q
E
S
G
Site 14
S128
I
E
T
S
S
N
H
S
Q
E
S
G
R
E
T
Site 15
S131
S
S
N
H
S
Q
E
S
G
R
E
T
P
S
S
Site 16
T135
S
Q
E
S
G
R
E
T
P
S
S
T
Q
A
S
Site 17
S137
E
S
G
R
E
T
P
S
S
T
Q
A
S
S
V
Site 18
S138
S
G
R
E
T
P
S
S
T
Q
A
S
S
V
N
Site 19
T139
G
R
E
T
P
S
S
T
Q
A
S
S
V
N
G
Site 20
S142
T
P
S
S
T
Q
A
S
S
V
N
G
T
D
D
Site 21
S143
P
S
S
T
Q
A
S
S
V
N
G
T
D
D
E
Site 22
T147
Q
A
S
S
V
N
G
T
D
D
E
K
A
S
H
Site 23
S164
P
A
N
T
H
L
K
S
E
N
D
K
L
K
I
Site 24
T174
D
K
L
K
I
A
L
T
Q
S
A
A
N
V
K
Site 25
T189
K
W
E
I
E
L
Q
T
L
R
E
S
N
A
R
Site 26
S193
E
L
Q
T
L
R
E
S
N
A
R
L
T
T
A
Site 27
T198
R
E
S
N
A
R
L
T
T
A
L
Q
E
S
A
Site 28
T199
E
S
N
A
R
L
T
T
A
L
Q
E
S
A
A
Site 29
S207
A
L
Q
E
S
A
A
S
V
E
Q
W
K
R
Q
Site 30
S237
D
E
L
E
E
Q
C
S
E
I
N
R
E
K
E
Site 31
S274
L
K
D
L
R
K
Q
S
E
I
I
P
Q
L
M
Site 32
S282
E
I
I
P
Q
L
M
S
E
C
E
Y
V
S
E
Site 33
Y286
Q
L
M
S
E
C
E
Y
V
S
E
K
L
E
A
Site 34
T310
D
K
V
R
S
L
K
T
D
I
E
E
S
K
Y
Site 35
S315
L
K
T
D
I
E
E
S
K
Y
R
Q
R
H
L
Site 36
Y317
T
D
I
E
E
S
K
Y
R
Q
R
H
L
K
V
Site 37
S348
H
D
F
R
R
G
L
S
K
L
G
T
D
N
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation