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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LTBP3
Full Name:
Latent-transforming growth factor beta-binding protein 3
Alias:
Flj00070; Flj33431; Flj39893; Flj42533; Flj44138; Latent tgf beta binding protein 3; Latent transforming growth factor beta binding protein 3; Latent transforming growth factor beta binding protein 3 isoform 1; Latent transforming growth factor beta binding protein 3 isoform 2; Latent-transforming growth factor beta-binding protein 3; Ltbp2; Ltbp3; Ltbp-3; Ltbp3 protein; Pp6425
Type:
Mass (Da):
139360
Number AA:
UniProt ID:
Q9NS15
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0019838
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S99
L
I
G
E
N
G
H
S
T
D
T
L
T
G
S
Site 2
T100
I
G
E
N
G
H
S
T
D
T
L
T
G
S
G
Site 3
T102
E
N
G
H
S
T
D
T
L
T
G
S
G
F
R
Site 4
T104
G
H
S
T
D
T
L
T
G
S
G
F
R
V
V
Site 5
T151
A
G
G
A
G
G
G
T
G
G
S
G
P
G
L
Site 6
S154
A
G
G
G
T
G
G
S
G
P
G
L
S
R
T
Site 7
S159
G
G
S
G
P
G
L
S
R
T
G
A
L
S
T
Site 8
T161
S
G
P
G
L
S
R
T
G
A
L
S
T
G
A
Site 9
S178
P
L
A
P
E
G
D
S
V
A
S
K
H
A
I
Site 10
S247
V
Q
V
H
R
I
E
S
S
N
A
E
S
A
A
Site 11
S248
Q
V
H
R
I
E
S
S
N
A
E
S
A
A
P
Site 12
S252
I
E
S
S
N
A
E
S
A
A
P
S
Q
H
L
Site 13
S256
N
A
E
S
A
A
P
S
Q
H
L
L
P
H
P
Site 14
S266
L
L
P
H
P
K
P
S
H
P
R
P
P
T
Q
Site 15
T272
P
S
H
P
R
P
P
T
Q
K
P
L
G
R
C
Site 16
T283
L
G
R
C
F
Q
D
T
L
P
K
Q
P
C
G
Site 17
S291
L
P
K
Q
P
C
G
S
N
P
L
P
G
L
T
Site 18
T325
K
C
P
Q
L
Q
Y
T
G
V
Q
K
P
G
P
Site 19
Y345
G
A
D
C
P
Q
G
Y
K
R
L
N
S
T
H
Site 20
Y377
C
L
N
N
P
G
S
Y
R
C
V
C
P
P
G
Site 21
S386
C
V
C
P
P
G
H
S
L
G
P
S
R
T
Q
Site 22
S390
P
G
H
S
L
G
P
S
R
T
Q
C
I
A
D
Site 23
T392
H
S
L
G
P
S
R
T
Q
C
I
A
D
K
P
Site 24
S403
A
D
K
P
E
E
K
S
L
C
F
R
L
V
S
Site 25
S410
S
L
C
F
R
L
V
S
P
E
H
Q
C
Q
H
Site 26
T420
H
Q
C
Q
H
P
L
T
T
R
L
T
R
Q
L
Site 27
T445
A
R
C
Q
R
C
P
T
D
G
T
A
A
F
K
Site 28
T448
Q
R
C
P
T
D
G
T
A
A
F
K
E
I
C
Site 29
Y461
I
C
P
A
G
K
G
Y
H
I
L
T
S
H
Q
Site 30
T465
G
K
G
Y
H
I
L
T
S
H
Q
T
L
T
I
Site 31
T471
L
T
S
H
Q
T
L
T
I
Q
G
E
S
D
F
Site 32
S479
I
Q
G
E
S
D
F
S
L
F
L
H
P
D
G
Site 33
S496
K
P
Q
Q
L
P
E
S
P
S
Q
A
P
P
P
Site 34
S498
Q
Q
L
P
E
S
P
S
Q
A
P
P
P
E
D
Site 35
T513
T
E
E
E
R
G
V
T
T
D
S
P
V
S
E
Site 36
T514
E
E
E
R
G
V
T
T
D
S
P
V
S
E
E
Site 37
S516
E
R
G
V
T
T
D
S
P
V
S
E
E
R
S
Site 38
S519
V
T
T
D
S
P
V
S
E
E
R
S
V
Q
Q
Site 39
S523
S
P
V
S
E
E
R
S
V
Q
Q
S
H
P
T
Site 40
S527
E
E
R
S
V
Q
Q
S
H
P
T
A
T
T
T
Site 41
T534
S
H
P
T
A
T
T
T
P
A
R
P
Y
P
E
Site 42
Y539
T
T
T
P
A
R
P
Y
P
E
L
I
S
R
P
Site 43
S544
R
P
Y
P
E
L
I
S
R
P
S
P
P
T
M
Site 44
S547
P
E
L
I
S
R
P
S
P
P
T
M
R
W
F
Site 45
T550
I
S
R
P
S
P
P
T
M
R
W
F
L
P
D
Site 46
S563
P
D
L
P
P
S
R
S
A
V
E
I
A
P
T
Site 47
T570
S
A
V
E
I
A
P
T
Q
V
T
E
T
D
E
Site 48
Y597
C
V
P
G
P
P
D
Y
S
C
H
C
N
P
G
Site 49
T635
G
R
G
I
C
M
N
T
G
G
S
Y
N
C
H
Site 50
S638
I
C
M
N
T
G
G
S
Y
N
C
H
C
N
R
Site 51
Y639
C
M
N
T
G
G
S
Y
N
C
H
C
N
R
G
Site 52
Y647
N
C
H
C
N
R
G
Y
R
L
H
V
G
A
G
Site 53
Y688
G
H
Y
K
C
N
C
Y
P
G
Y
R
L
K
A
Site 54
Y691
K
C
N
C
Y
P
G
Y
R
L
K
A
S
R
P
Site 55
S696
P
G
Y
R
L
K
A
S
R
P
P
V
C
E
D
Site 56
S711
I
D
E
C
R
D
P
S
S
C
P
D
G
K
C
Site 57
S712
D
E
C
R
D
P
S
S
C
P
D
G
K
C
E
Site 58
Y734
C
I
A
C
Q
P
G
Y
R
S
Q
G
G
G
A
Site 59
S736
A
C
Q
P
G
Y
R
S
Q
G
G
G
A
C
R
Site 60
S755
C
A
E
G
S
P
C
S
P
G
W
C
E
N
L
Site 61
T769
L
P
G
S
F
R
C
T
C
A
Q
G
Y
A
P
Site 62
T803
D
N
G
I
C
S
N
T
P
G
S
F
Q
C
Q
Site 63
S818
C
L
S
G
Y
H
L
S
R
D
R
S
H
C
E
Site 64
S822
Y
H
L
S
R
D
R
S
H
C
E
D
I
D
E
Site 65
S875
D
E
C
S
Q
D
P
S
L
C
L
P
H
G
A
Site 66
Y890
C
K
N
L
Q
G
S
Y
V
C
V
C
D
E
G
Site 67
Y920
P
H
H
K
K
E
C
Y
L
N
F
D
D
T
V
Site 68
Y962
E
I
Y
P
C
P
V
Y
S
S
A
E
F
H
S
Site 69
S969
Y
S
S
A
E
F
H
S
L
C
P
D
G
K
G
Site 70
Y986
Q
D
N
N
I
V
N
Y
G
I
P
A
H
R
D
Site 71
S1002
D
E
C
M
L
F
G
S
E
I
C
K
E
G
K
Site 72
Y1017
C
V
N
T
Q
P
G
Y
E
C
Y
C
K
Q
G
Site 73
Y1027
Y
C
K
Q
G
F
Y
Y
D
G
N
L
L
E
C
Site 74
Y1058
C
E
N
T
R
G
G
Y
R
C
A
C
T
P
P
Site 75
T1063
G
G
Y
R
C
A
C
T
P
P
A
E
Y
S
P
Site 76
S1069
C
T
P
P
A
E
Y
S
P
A
Q
R
Q
C
L
Site 77
S1077
P
A
Q
R
Q
C
L
S
P
E
E
M
D
V
D
Site 78
S1117
P
P
W
V
P
G
P
S
G
R
D
C
Q
L
P
Site 79
S1126
R
D
C
Q
L
P
E
S
P
A
E
R
A
P
E
Site 80
S1140
E
R
R
D
V
C
W
S
Q
R
G
E
D
G
M
Site 81
S1184
C
P
P
R
G
A
G
S
H
C
P
T
S
Q
S
Site 82
T1188
G
A
G
S
H
C
P
T
S
Q
S
E
S
N
S
Site 83
S1189
A
G
S
H
C
P
T
S
Q
S
E
S
N
S
F
Site 84
S1191
S
H
C
P
T
S
Q
S
E
S
N
S
F
W
D
Site 85
S1193
C
P
T
S
Q
S
E
S
N
S
F
W
D
T
S
Site 86
S1195
T
S
Q
S
E
S
N
S
F
W
D
T
S
P
L
Site 87
T1199
E
S
N
S
F
W
D
T
S
P
L
L
L
G
K
Site 88
S1200
S
N
S
F
W
D
T
S
P
L
L
L
G
K
P
Site 89
S1213
K
P
P
R
D
E
D
S
S
E
E
D
S
D
E
Site 90
S1214
P
P
R
D
E
D
S
S
E
E
D
S
D
E
C
Site 91
S1218
E
D
S
S
E
E
D
S
D
E
C
R
C
V
S
Site 92
S1225
S
D
E
C
R
C
V
S
G
R
C
V
P
R
P
Site 93
S1248
G
G
F
Q
L
D
A
S
R
A
R
C
V
D
I
Site 94
S1270
Q
R
G
L
L
C
K
S
E
R
C
V
N
T
S
Site 95
T1276
K
S
E
R
C
V
N
T
S
G
S
F
R
C
V
Site 96
S1277
S
E
R
C
V
N
T
S
G
S
F
R
C
V
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation