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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BAZ1A
Full Name:
Bromodomain adjacent to zinc finger domain protein 1A
Alias:
ACF1; ATP-dependent chromatin remodeling protein; ATP-utilizing chromatin assembly and remodeling factor 1; CHRAC subunit ACF1; WALp1; WCRF180; Williams syndrome transcription factor-related chromatin remodeling factor 180
Type:
Chromatin remodelling; Nucleus
Mass (Da):
178702
Number AA:
1556
UniProt ID:
Q9NRL2
International Prot ID:
IPI00412415
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y26
R
P
D
E
E
V
F
Y
C
K
V
T
N
E
I
Site 2
Y37
T
N
E
I
F
R
H
Y
D
D
F
F
E
R
T
Site 3
Y64
T
G
R
P
G
L
T
Y
Q
E
A
L
E
S
E
Site 4
S70
T
Y
Q
E
A
L
E
S
E
K
K
A
R
Q
N
Site 5
S80
K
A
R
Q
N
L
Q
S
F
P
E
P
L
I
I
Site 6
T96
V
L
Y
L
T
S
L
T
H
R
S
R
L
H
E
Site 7
Y116
F
A
Y
V
K
D
R
Y
F
V
E
E
T
V
E
Site 8
T121
D
R
Y
F
V
E
E
T
V
E
V
I
R
N
N
Site 9
S143
I
L
E
V
L
P
P
S
H
Q
N
G
F
A
N
Site 10
T160
V
N
S
V
D
G
E
T
I
I
I
S
D
S
D
Site 11
S164
D
G
E
T
I
I
I
S
D
S
D
D
S
E
T
Site 12
S166
E
T
I
I
I
S
D
S
D
D
S
E
T
Q
S
Site 13
S169
I
I
S
D
S
D
D
S
E
T
Q
S
C
S
F
Site 14
T171
S
D
S
D
D
S
E
T
Q
S
C
S
F
Q
N
Site 15
S173
S
D
D
S
E
T
Q
S
C
S
F
Q
N
G
K
Site 16
S175
D
S
E
T
Q
S
C
S
F
Q
N
G
K
K
K
Site 17
Y192
I
D
P
L
L
F
K
Y
K
V
Q
P
T
K
K
Site 18
S204
T
K
K
E
L
H
E
S
A
I
V
K
A
T
Q
Site 19
S213
I
V
K
A
T
Q
I
S
R
R
K
H
L
F
S
Site 20
S220
S
R
R
K
H
L
F
S
R
D
K
L
K
L
F
Site 21
Y249
K
A
S
S
L
S
T
Y
K
I
A
E
Q
D
F
Site 22
S257
K
I
A
E
Q
D
F
S
Y
F
F
P
D
D
P
Site 23
Y258
I
A
E
Q
D
F
S
Y
F
F
P
D
D
P
P
Site 24
T266
F
F
P
D
D
P
P
T
F
I
F
S
P
A
N
Site 25
S270
D
P
P
T
F
I
F
S
P
A
N
R
R
R
G
Site 26
S286
P
P
K
R
I
H
I
S
Q
E
D
N
V
A
N
Site 27
S299
A
N
K
Q
T
L
A
S
Y
R
S
K
A
T
K
Site 28
S319
L
K
Q
E
E
M
K
S
L
A
F
E
K
A
K
Site 29
Y388
L
R
E
E
K
R
K
Y
V
E
Y
L
K
Q
W
Site 30
Y391
E
K
R
K
Y
V
E
Y
L
K
Q
W
S
K
P
Site 31
S396
V
E
Y
L
K
Q
W
S
K
P
R
E
D
M
E
Site 32
T414
L
K
E
L
P
E
P
T
P
V
K
T
R
L
P
Site 33
T418
P
E
P
T
P
V
K
T
R
L
P
P
E
I
F
Site 34
T453
D
E
F
P
D
G
V
T
L
E
V
L
E
E
A
Site 35
S466
E
A
L
V
G
N
D
S
E
G
P
L
C
E
L
Site 36
T502
E
Q
L
T
D
A
D
T
K
D
L
T
E
A
L
Site 37
T506
D
A
D
T
K
D
L
T
E
A
L
D
E
D
A
Site 38
T516
L
D
E
D
A
D
P
T
K
S
A
L
S
A
V
Site 39
S518
E
D
A
D
P
T
K
S
A
L
S
A
V
A
S
Site 40
S538
P
Q
L
H
Q
G
C
S
L
K
S
L
D
L
D
Site 41
S541
H
Q
G
C
S
L
K
S
L
D
L
D
S
C
T
Site 42
S566
A
S
G
A
D
V
T
S
A
N
A
K
Y
R
Y
Site 43
Y573
S
A
N
A
K
Y
R
Y
Q
K
R
G
G
F
D
Site 44
T582
K
R
G
G
F
D
A
T
D
D
A
C
M
E
L
Site 45
S592
A
C
M
E
L
R
L
S
N
P
S
L
V
K
K
Site 46
S595
E
L
R
L
S
N
P
S
L
V
K
K
L
S
S
Site 47
S601
P
S
L
V
K
K
L
S
S
T
S
V
Y
D
L
Site 48
S602
S
L
V
K
K
L
S
S
T
S
V
Y
D
L
T
Site 49
T603
L
V
K
K
L
S
S
T
S
V
Y
D
L
T
P
Site 50
S604
V
K
K
L
S
S
T
S
V
Y
D
L
T
P
G
Site 51
Y606
K
L
S
S
T
S
V
Y
D
L
T
P
G
E
K
Site 52
T609
S
T
S
V
Y
D
L
T
P
G
E
K
M
K
I
Site 53
Y637
T
R
D
F
I
E
D
Y
V
D
I
L
R
Q
A
Site 54
S697
K
E
D
E
Q
R
N
S
T
A
D
I
S
I
G
Site 55
T698
E
D
E
Q
R
N
S
T
A
D
I
S
I
G
E
Site 56
S702
R
N
S
T
A
D
I
S
I
G
E
E
E
R
E
Site 57
T713
E
E
R
E
D
F
D
T
S
I
E
S
K
D
T
Site 58
S714
E
R
E
D
F
D
T
S
I
E
S
K
D
T
E
Site 59
T720
T
S
I
E
S
K
D
T
E
Q
K
E
L
D
Q
Site 60
T731
E
L
D
Q
D
M
V
T
E
D
E
D
D
P
G
Site 61
S739
E
D
E
D
D
P
G
S
H
K
R
G
R
R
G
Site 62
Y811
P
L
G
R
D
R
M
Y
R
R
Y
W
I
F
P
Site 63
Y814
R
D
R
M
Y
R
R
Y
W
I
F
P
S
I
P
Site 64
S819
R
R
Y
W
I
F
P
S
I
P
G
L
F
I
E
Site 65
Y829
G
L
F
I
E
E
D
Y
S
G
L
T
E
D
M
Site 66
S830
L
F
I
E
E
D
Y
S
G
L
T
E
D
M
L
Site 67
S842
D
M
L
L
P
R
P
S
S
F
Q
N
N
V
Q
Site 68
S843
M
L
L
P
R
P
S
S
F
Q
N
N
V
Q
S
Site 69
S850
S
F
Q
N
N
V
Q
S
Q
D
P
Q
V
S
T
Site 70
S865
K
T
G
E
P
L
M
S
E
S
T
S
N
I
D
Site 71
S867
G
E
P
L
M
S
E
S
T
S
N
I
D
Q
G
Site 72
S869
P
L
M
S
E
S
T
S
N
I
D
Q
G
P
R
Site 73
S879
D
Q
G
P
R
D
H
S
V
Q
L
P
K
P
V
Site 74
S910
Q
L
I
E
A
L
N
S
R
G
H
R
E
S
A
Site 75
S916
N
S
R
G
H
R
E
S
A
L
K
E
T
L
L
Site 76
S927
E
T
L
L
Q
E
K
S
R
I
C
A
Q
L
A
Site 77
S937
C
A
Q
L
A
R
F
S
E
E
K
F
H
F
S
Site 78
S944
S
E
E
K
F
H
F
S
D
K
P
Q
P
D
S
Site 79
S951
S
D
K
P
Q
P
D
S
K
P
T
Y
S
R
G
Site 80
T954
P
Q
P
D
S
K
P
T
Y
S
R
G
R
S
S
Site 81
Y955
Q
P
D
S
K
P
T
Y
S
R
G
R
S
S
N
Site 82
S956
P
D
S
K
P
T
Y
S
R
G
R
S
S
N
A
Site 83
S960
P
T
Y
S
R
G
R
S
S
N
A
Y
D
P
S
Site 84
S961
T
Y
S
R
G
R
S
S
N
A
Y
D
P
S
Q
Site 85
Y964
R
G
R
S
S
N
A
Y
D
P
S
Q
M
C
A
Site 86
S967
S
S
N
A
Y
D
P
S
Q
M
C
A
E
K
Q
Site 87
T994
E
D
R
I
Y
Q
G
T
L
G
A
I
K
V
T
Site 88
S1008
T
D
R
H
I
W
R
S
A
L
E
S
G
R
Y
Site 89
S1012
I
W
R
S
A
L
E
S
G
R
Y
E
L
L
S
Site 90
Y1015
S
A
L
E
S
G
R
Y
E
L
L
S
E
E
N
Site 91
S1019
S
G
R
Y
E
L
L
S
E
E
N
K
E
N
G
Site 92
T1030
K
E
N
G
I
I
K
T
V
N
E
D
V
E
E
Site 93
T1057
D
R
L
L
G
I
K
T
E
T
P
S
T
V
S
Site 94
T1059
L
L
G
I
K
T
E
T
P
S
T
V
S
T
N
Site 95
S1061
G
I
K
T
E
T
P
S
T
V
S
T
N
A
S
Site 96
T1062
I
K
T
E
T
P
S
T
V
S
T
N
A
S
T
Site 97
S1064
T
E
T
P
S
T
V
S
T
N
A
S
T
P
Q
Site 98
T1065
E
T
P
S
T
V
S
T
N
A
S
T
P
Q
S
Site 99
S1068
S
T
V
S
T
N
A
S
T
P
Q
S
V
S
S
Site 100
T1069
T
V
S
T
N
A
S
T
P
Q
S
V
S
S
V
Site 101
S1072
T
N
A
S
T
P
Q
S
V
S
S
V
V
H
Y
Site 102
S1103
L
K
A
P
L
D
A
S
D
S
G
R
S
Y
K
Site 103
S1105
A
P
L
D
A
S
D
S
G
R
S
Y
K
T
V
Site 104
Y1109
A
S
D
S
G
R
S
Y
K
T
V
L
D
R
W
Site 105
T1111
D
S
G
R
S
Y
K
T
V
L
D
R
W
R
E
Site 106
S1119
V
L
D
R
W
R
E
S
L
L
S
S
A
S
L
Site 107
S1122
R
W
R
E
S
L
L
S
S
A
S
L
S
Q
V
Site 108
S1123
W
R
E
S
L
L
S
S
A
S
L
S
Q
V
F
Site 109
S1139
H
L
S
T
L
D
R
S
V
I
W
S
K
S
I
Site 110
S1143
L
D
R
S
V
I
W
S
K
S
I
L
N
A
R
Site 111
S1145
R
S
V
I
W
S
K
S
I
L
N
A
R
C
K
Site 112
T1175
G
C
D
R
G
H
H
T
Y
C
V
R
P
K
L
Site 113
Y1176
C
D
R
G
H
H
T
Y
C
V
R
P
K
L
K
Site 114
T1184
C
V
R
P
K
L
K
T
V
P
E
G
D
W
F
Site 115
S1201
E
C
R
P
K
Q
R
S
R
R
L
S
S
R
Q
Site 116
S1205
K
Q
R
S
R
R
L
S
S
R
Q
R
P
S
L
Site 117
S1206
Q
R
S
R
R
L
S
S
R
Q
R
P
S
L
E
Site 118
S1211
L
S
S
R
Q
R
P
S
L
E
S
D
E
D
V
Site 119
S1214
R
Q
R
P
S
L
E
S
D
E
D
V
E
D
S
Site 120
S1221
S
D
E
D
V
E
D
S
M
G
G
E
D
D
E
Site 121
S1238
G
D
E
E
E
G
Q
S
E
E
E
E
Y
E
V
Site 122
Y1243
G
Q
S
E
E
E
E
Y
E
V
E
Q
D
E
D
Site 123
S1252
V
E
Q
D
E
D
D
S
Q
E
E
E
E
V
S
Site 124
S1259
S
Q
E
E
E
E
V
S
L
P
K
R
G
R
P
Site 125
T1274
Q
V
R
L
P
V
K
T
R
G
K
L
S
S
S
Site 126
S1279
V
K
T
R
G
K
L
S
S
S
F
S
S
R
G
Site 127
S1280
K
T
R
G
K
L
S
S
S
F
S
S
R
G
Q
Site 128
S1281
T
R
G
K
L
S
S
S
F
S
S
R
G
Q
Q
Site 129
S1283
G
K
L
S
S
S
F
S
S
R
G
Q
Q
Q
E
Site 130
S1284
K
L
S
S
S
F
S
S
R
G
Q
Q
Q
E
P
Site 131
Y1294
Q
Q
Q
E
P
G
R
Y
P
S
R
S
Q
Q
S
Site 132
S1296
Q
E
P
G
R
Y
P
S
R
S
Q
Q
S
T
P
Site 133
S1298
P
G
R
Y
P
S
R
S
Q
Q
S
T
P
K
T
Site 134
S1301
Y
P
S
R
S
Q
Q
S
T
P
K
T
T
V
S
Site 135
T1302
P
S
R
S
Q
Q
S
T
P
K
T
T
V
S
S
Site 136
T1305
S
Q
Q
S
T
P
K
T
T
V
S
S
K
T
G
Site 137
T1306
Q
Q
S
T
P
K
T
T
V
S
S
K
T
G
R
Site 138
S1309
T
P
K
T
T
V
S
S
K
T
G
R
S
L
R
Site 139
T1311
K
T
T
V
S
S
K
T
G
R
S
L
R
K
I
Site 140
S1314
V
S
S
K
T
G
R
S
L
R
K
I
N
S
A
Site 141
S1320
R
S
L
R
K
I
N
S
A
P
P
T
E
T
K
Site 142
T1324
K
I
N
S
A
P
P
T
E
T
K
S
L
R
I
Site 143
T1326
N
S
A
P
P
T
E
T
K
S
L
R
I
A
S
Site 144
S1328
A
P
P
T
E
T
K
S
L
R
I
A
S
R
S
Site 145
S1333
T
K
S
L
R
I
A
S
R
S
T
R
H
S
H
Site 146
S1335
S
L
R
I
A
S
R
S
T
R
H
S
H
G
P
Site 147
T1336
L
R
I
A
S
R
S
T
R
H
S
H
G
P
L
Site 148
S1339
A
S
R
S
T
R
H
S
H
G
P
L
Q
A
D
Site 149
S1353
D
V
F
V
E
L
L
S
P
R
R
K
R
R
G
Site 150
S1363
R
K
R
R
G
R
K
S
A
N
N
T
P
E
N
Site 151
T1367
G
R
K
S
A
N
N
T
P
E
N
S
P
N
F
Site 152
S1371
A
N
N
T
P
E
N
S
P
N
F
P
N
F
R
Site 153
S1384
F
R
V
I
A
T
K
S
S
E
Q
S
R
S
V
Site 154
S1385
R
V
I
A
T
K
S
S
E
Q
S
R
S
V
N
Site 155
S1388
A
T
K
S
S
E
Q
S
R
S
V
N
I
A
S
Site 156
S1390
K
S
S
E
Q
S
R
S
V
N
I
A
S
K
L
Site 157
S1398
V
N
I
A
S
K
L
S
L
Q
E
S
E
S
K
Site 158
S1402
S
K
L
S
L
Q
E
S
E
S
K
R
R
C
R
Site 159
S1404
L
S
L
Q
E
S
E
S
K
R
R
C
R
K
R
Site 160
S1413
R
R
C
R
K
R
Q
S
P
E
P
S
P
V
T
Site 161
S1417
K
R
Q
S
P
E
P
S
P
V
T
L
G
R
R
Site 162
T1420
S
P
E
P
S
P
V
T
L
G
R
R
S
S
G
Site 163
S1425
P
V
T
L
G
R
R
S
S
G
R
Q
G
G
V
Site 164
S1426
V
T
L
G
R
R
S
S
G
R
Q
G
G
V
H
Site 165
S1451
E
L
V
R
H
D
D
S
W
P
F
L
K
L
V
Site 166
Y1466
S
K
I
Q
V
P
D
Y
Y
D
I
I
K
K
P
Site 167
Y1467
K
I
Q
V
P
D
Y
Y
D
I
I
K
K
P
I
Site 168
Y1488
E
K
V
N
K
C
E
Y
K
L
A
S
E
F
I
Site 169
Y1508
M
F
S
N
C
F
E
Y
N
P
R
N
T
S
E
Site 170
T1513
F
E
Y
N
P
R
N
T
S
E
A
K
A
G
T
Site 171
S1514
E
Y
N
P
R
N
T
S
E
A
K
A
G
T
R
Site 172
T1538
Q
K
L
G
L
H
V
T
P
S
N
V
D
Q
V
Site 173
S1540
L
G
L
H
V
T
P
S
N
V
D
Q
V
S
T
Site 174
S1546
P
S
N
V
D
Q
V
S
T
P
P
A
A
K
K
Site 175
T1547
S
N
V
D
Q
V
S
T
P
P
A
A
K
K
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation