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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PAPOLB
Full Name:
Poly(A) polymerase beta
Alias:
EC 2.7.7.19; Papob; Papolb; Papt; Poly(a) polymerase beta (testis specific); Testis-specific poly(a) polymerase; Tpap
Type:
Cytoplasm, Nucleus protein
Mass (Da):
71681
Number AA:
636
UniProt ID:
Q9NRJ5
International Prot ID:
IPI00024525
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003723
GO:0004652
PhosphoSite+
KinaseNET
Biological Process:
GO:0043631
GO:0006397
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y20
P
A
P
P
P
N
R
Y
G
V
S
S
P
I
S
Site 2
S23
P
P
N
R
Y
G
V
S
S
P
I
S
L
A
V
Site 3
S24
P
N
R
Y
G
V
S
S
P
I
S
L
A
V
P
Site 4
T39
K
E
T
D
C
L
L
T
Q
R
L
I
E
T
L
Site 5
S80
K
E
W
I
R
E
I
S
E
S
K
S
L
P
Q
Site 6
S82
W
I
R
E
I
S
E
S
K
S
L
P
Q
S
V
Site 7
S84
R
E
I
S
E
S
K
S
L
P
Q
S
V
I
E
Site 8
S88
E
S
K
S
L
P
Q
S
V
I
E
N
V
G
G
Site 9
T109
S
Y
R
L
G
V
H
T
K
G
A
D
I
D
A
Site 10
S122
D
A
L
C
V
A
P
S
H
V
D
R
S
D
F
Site 11
S127
A
P
S
H
V
D
R
S
D
F
F
T
S
F
Y
Site 12
T131
V
D
R
S
D
F
F
T
S
F
Y
A
K
L
K
Site 13
S132
D
R
S
D
F
F
T
S
F
Y
A
K
L
K
L
Site 14
Y134
S
D
F
F
T
S
F
Y
A
K
L
K
L
Q
E
Site 15
S188
D
L
D
L
R
D
D
S
L
L
K
N
L
D
I
Site 16
T223
N
I
D
N
F
R
L
T
L
R
A
I
K
L
W
Site 17
Y310
R
V
N
P
S
D
R
Y
H
L
M
P
I
I
T
Site 18
T317
Y
H
L
M
P
I
I
T
P
A
Y
P
Q
Q
N
Site 19
Y320
M
P
I
I
T
P
A
Y
P
Q
Q
N
S
T
Y
Site 20
S325
P
A
Y
P
Q
Q
N
S
T
Y
N
V
S
I
S
Site 21
T326
A
Y
P
Q
Q
N
S
T
Y
N
V
S
I
S
T
Site 22
Y327
Y
P
Q
Q
N
S
T
Y
N
V
S
I
S
T
R
Site 23
S354
I
T
H
E
I
L
L
S
K
A
E
W
S
K
L
Site 24
S366
S
K
L
F
E
A
P
S
F
F
Q
K
Y
K
H
Site 25
S420
L
A
H
V
N
P
Q
S
F
P
A
P
K
E
N
Site 26
S449
G
L
K
K
P
D
N
S
E
I
L
S
I
D
L
Site 27
S453
P
D
N
S
E
I
L
S
I
D
L
T
Y
D
I
Site 28
S462
D
L
T
Y
D
I
Q
S
F
T
D
T
V
Y
R
Site 29
T466
D
I
Q
S
F
T
D
T
V
Y
R
Q
A
V
N
Site 30
Y468
Q
S
F
T
D
T
V
Y
R
Q
A
V
N
S
K
Site 31
T516
S
T
E
G
R
R
L
T
D
L
N
D
S
S
F
Site 32
S521
R
L
T
D
L
N
D
S
S
F
D
L
S
A
G
Site 33
S522
L
T
D
L
N
D
S
S
F
D
L
S
A
G
C
Site 34
S526
N
D
S
S
F
D
L
S
A
G
C
E
N
S
M
Site 35
S532
L
S
A
G
C
E
N
S
M
S
V
P
S
S
T
Site 36
S534
A
G
C
E
N
S
M
S
V
P
S
S
T
S
T
Site 37
S538
N
S
M
S
V
P
S
S
T
S
T
M
K
T
G
Site 38
S540
M
S
V
P
S
S
T
S
T
M
K
T
G
P
L
Site 39
T541
S
V
P
S
S
T
S
T
M
K
T
G
P
L
I
Site 40
T544
S
S
T
S
T
M
K
T
G
P
L
I
S
S
S
Site 41
S549
M
K
T
G
P
L
I
S
S
S
Q
G
R
N
S
Site 42
S550
K
T
G
P
L
I
S
S
S
Q
G
R
N
S
P
Site 43
S551
T
G
P
L
I
S
S
S
Q
G
R
N
S
P
A
Site 44
S556
S
S
S
Q
G
R
N
S
P
A
L
A
V
M
T
Site 45
T581
F
S
L
Q
Q
V
N
T
N
E
S
S
G
V
A
Site 46
S592
S
G
V
A
L
N
E
S
I
P
H
A
V
S
Q
Site 47
S598
E
S
I
P
H
A
V
S
Q
P
A
I
S
P
S
Site 48
S605
S
Q
P
A
I
S
P
S
P
K
A
M
V
A
R
Site 49
S621
V
S
S
T
C
L
I
S
H
P
D
L
Q
E
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation