PhosphoNET

           
Protein Info 
   
Short Name:  AAAS
Full Name:  Aladin
Alias:  AAA; AAASb; Achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A); Adracala; Adracalin; ALADIN; GL003
Type:  Nuclear envelope; Membrane protein, integral
Mass (Da):  59574
Number AA:  546
UniProt ID:  Q9NRG9
International Prot ID:  IPI00024143
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005635  GO:0005643  GO:0031967 Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0003008  GO:0006810  GO:0006913 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y19PRGQVTLYEHNNELV
Site 2S29NNELVTGSSYESPPP
Site 3S30NELVTGSSYESPPPD
Site 4Y31ELVTGSSYESPPPDF
Site 5S33VTGSSYESPPPDFRG
Site 6T51NLPVLQLTKDPLKTP
Site 7T57LTKDPLKTPGRLDHG
Site 8T65PGRLDHGTRTAFIHH
Site 9S99VLNEIANSEEEVFEW
Site 10S181SVRVYNASSTIVPSL
Site 11T183RVYNASSTIVPSLKH
Site 12S187ASSTIVPSLKHRLQR
Site 13S198RLQRNVASLAWKPLS
Site 14S226IWTLDPTSLSTRPSS
Site 15S228TLDPTSLSTRPSSGC
Site 16T229LDPTSLSTRPSSGCA
Site 17S232TSLSTRPSSGCAQVL
Site 18S233SLSTRPSSGCAQVLS
Site 19S240SGCAQVLSHPGHTPV
Site 20S249PGHTPVTSLAWAPSG
Site 21S261PSGGRLLSASPVDAA
Site 22T333TLSGRCQTGCWSPDG
Site 23S337RCQTGCWSPDGSRLL
Site 24S357EPLIYSLSFPERCGE
Site 25T388LSETTIQTPDGEERL
Site 26S401RLGGEAHSMVWDPSG
Site 27S407HSMVWDPSGERLAVL
Site 28T459GAQPQLITFHPSFNK
Site 29S471FNKGALLSVGWSTGR
Site 30S495NAQFPRFSPVLGRAQ
Site 31S511PPAGGGGSIHDLPLF
Site 32T519IHDLPLFTETSPTSA
Site 33T521DLPLFTETSPTSAPW
Site 34S522LPLFTETSPTSAPWD
Site 35T524LFTETSPTSAPWDPL
Site 36S525FTETSPTSAPWDPLP
Site 37S541PPPVLPHSPHSHL__
Site 38S544VLPHSPHSHL_____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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