KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SMYD2
Full Name:
SET and MYND domain-containing protein 2
Alias:
HSKM-B; SET and MYND domain containing 2
Type:
Mass (Da):
49688
Number AA:
433
UniProt ID:
Q9NRG4
International Prot ID:
IPI00024641
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
G
G
L
E
R
F
C
S
P
G
K
G
R
G
L
Site 2
S35
Q
V
G
D
L
L
F
S
C
P
A
Y
A
Y
V
Site 3
T44
P
A
Y
A
Y
V
L
T
V
N
E
R
G
N
H
Site 4
Y54
E
R
G
N
H
C
E
Y
C
F
T
R
K
E
G
Site 5
S63
F
T
R
K
E
G
L
S
K
C
G
R
C
K
Q
Site 6
Y73
G
R
C
K
Q
A
F
Y
C
N
V
E
C
Q
K
Site 7
T109
P
S
E
T
V
R
L
T
A
R
I
L
A
K
Q
Site 8
T123
Q
K
I
H
P
E
R
T
P
S
E
K
L
L
A
Site 9
S125
I
H
P
E
R
T
P
S
E
K
L
L
A
V
K
Site 10
S151
E
K
K
D
L
I
Q
S
D
I
A
A
L
H
H
Site 11
S192
T
I
E
D
E
E
L
S
H
L
G
S
A
I
F
Site 12
T238
K
P
G
E
E
V
F
T
S
Y
I
D
L
L
Y
Site 13
S239
P
G
E
E
V
F
T
S
Y
I
D
L
L
Y
P
Site 14
Y240
G
E
E
V
F
T
S
Y
I
D
L
L
Y
P
T
Site 15
Y245
T
S
Y
I
D
L
L
Y
P
T
E
D
R
N
D
Site 16
Y258
N
D
R
L
R
D
S
Y
F
F
T
C
E
C
Q
Site 17
S283
K
V
E
I
R
K
L
S
D
P
P
K
A
E
A
Site 18
Y297
A
I
R
D
M
V
R
Y
A
R
N
V
I
E
E
Site 19
Y311
E
F
R
R
A
K
H
Y
K
S
P
S
E
L
L
Site 20
S313
R
R
A
K
H
Y
K
S
P
S
E
L
L
E
I
Site 21
S315
A
K
H
Y
K
S
P
S
E
L
L
E
I
C
E
Site 22
S330
L
S
Q
E
K
M
S
S
V
F
E
D
S
N
V
Site 23
Y374
I
K
P
Y
S
K
H
Y
P
L
Y
S
L
N
V
Site 24
Y377
Y
S
K
H
Y
P
L
Y
S
L
N
V
A
S
M
Site 25
Y392
W
L
K
L
G
R
L
Y
M
G
L
E
H
K
A
Site 26
Y422
A
H
G
K
D
H
P
Y
I
S
E
I
K
Q
E
Site 27
S424
G
K
D
H
P
Y
I
S
E
I
K
Q
E
I
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation