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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPTBN4
Full Name:
Spectrin beta chain, brain 4
Alias:
Beta-V spectrin; BSPECV; Spectrin, non-erythroid beta chain 4; SPTN5
Type:
Cytoskeletal protein
Mass (Da):
416835
Number AA:
3674
UniProt ID:
Q9NRC6
International Prot ID:
IPI00219168
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0016020
GO:0008091
Uniprot
OncoNet
Molecular Function:
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
GO:0030036
GO:0051693
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
G
Q
P
H
S
P
R
E
L
L
G
A
Site 2
S19
L
G
A
A
G
H
R
S
R
R
P
S
T
E
L
Site 3
S23
G
H
R
S
R
R
P
S
T
E
L
R
V
P
P
Site 4
T24
H
R
S
R
R
P
S
T
E
L
R
V
P
P
S
Site 5
S31
T
E
L
R
V
P
P
S
P
S
L
T
M
D
S
Site 6
S33
L
R
V
P
P
S
P
S
L
T
M
D
S
Q
Y
Site 7
T35
V
P
P
S
P
S
L
T
M
D
S
Q
Y
E
T
Site 8
S38
S
P
S
L
T
M
D
S
Q
Y
E
T
G
H
I
Site 9
Y40
S
L
T
M
D
S
Q
Y
E
T
G
H
I
R
K
Site 10
T42
T
M
D
S
Q
Y
E
T
G
H
I
R
K
L
Q
Site 11
S106
G
E
A
L
P
P
P
S
R
G
R
L
R
V
H
Site 12
S164
R
F
Q
I
S
H
I
S
L
D
K
E
E
F
G
Site 13
S173
D
K
E
E
F
G
A
S
A
A
L
L
S
T
K
Site 14
Y194
C
Q
R
K
T
A
S
Y
T
N
V
N
I
T
D
Site 15
T200
S
Y
T
N
V
N
I
T
D
F
S
R
S
W
S
Site 16
S203
N
V
N
I
T
D
F
S
R
S
W
S
D
G
L
Site 17
S205
N
I
T
D
F
S
R
S
W
S
D
G
L
G
F
Site 18
S207
T
D
F
S
R
S
W
S
D
G
L
G
F
N
A
Site 19
Y226
H
R
P
D
L
L
D
Y
G
S
L
R
P
D
R
Site 20
S228
P
D
L
L
D
Y
G
S
L
R
P
D
R
P
L
Site 21
S269
A
A
Q
P
D
E
R
S
I
M
T
Y
V
S
L
Site 22
Y273
D
E
R
S
I
M
T
Y
V
S
L
Y
Y
H
Y
Site 23
Y277
I
M
T
Y
V
S
L
Y
Y
H
Y
C
S
R
L
Site 24
Y278
M
T
Y
V
S
L
Y
Y
H
Y
C
S
R
L
H
Site 25
Y280
Y
V
S
L
Y
Y
H
Y
C
S
R
L
H
Q
G
Site 26
T289
S
R
L
H
Q
G
Q
T
V
Q
R
R
L
T
K
Site 27
T295
Q
T
V
Q
R
R
L
T
K
I
L
L
Q
L
Q
Site 28
T309
Q
E
T
E
L
L
Q
T
Q
Y
E
Q
L
V
A
Site 29
S337
E
A
R
D
F
P
D
S
L
P
A
M
R
Q
L
Site 30
T349
R
Q
L
L
A
A
F
T
I
F
R
T
Q
E
K
Site 31
T353
A
A
F
T
I
F
R
T
Q
E
K
P
P
R
L
Site 32
T375
A
L
L
F
R
L
Q
T
A
L
Q
A
Q
N
R
Site 33
S411
E
W
A
E
A
A
R
S
Q
A
L
Q
Q
R
L
Site 34
T426
L
Q
L
Q
R
L
E
T
L
A
R
R
F
Q
R
Site 35
S440
R
K
A
A
L
R
E
S
F
L
K
D
A
E
Q
Site 36
Y498
D
I
L
R
Q
E
Q
Y
H
S
W
A
D
V
A
Site 37
S500
L
R
Q
E
Q
Y
H
S
W
A
D
V
A
R
R
Site 38
T512
A
R
R
Q
E
E
V
T
V
R
W
Q
R
L
L
Site 39
S558
E
L
Q
E
P
A
R
S
T
A
C
G
Q
Q
L
Site 40
T559
L
Q
E
P
A
R
S
T
A
C
G
Q
Q
L
A
Site 41
S590
S
A
H
G
A
H
V
S
H
L
A
Q
Q
T
A
Site 42
S602
Q
T
A
E
L
D
S
S
L
G
T
S
V
E
V
Site 43
S706
V
R
R
G
R
D
L
S
A
R
R
P
P
T
Q
Site 44
T712
L
S
A
R
R
P
P
T
Q
P
D
P
G
E
R
Site 45
T732
G
G
W
Q
L
L
Q
T
R
V
V
G
R
G
A
Site 46
S759
A
D
A
A
E
A
A
S
W
L
R
E
R
R
S
Site 47
S766
S
W
L
R
E
R
R
S
S
L
E
R
A
S
C
Site 48
S767
W
L
R
E
R
R
S
S
L
E
R
A
S
C
G
Site 49
S772
R
S
S
L
E
R
A
S
C
G
Q
D
Q
A
A
Site 50
S812
E
E
Q
G
R
A
A
S
A
R
A
S
L
F
T
Site 51
S825
F
T
V
N
S
A
L
S
P
P
G
E
S
L
R
Site 52
S830
A
L
S
P
P
G
E
S
L
R
N
P
G
P
W
Site 53
S838
L
R
N
P
G
P
W
S
E
A
S
C
H
P
G
Site 54
S841
P
G
P
W
S
E
A
S
C
H
P
G
P
G
D
Site 55
T866
D
P
D
F
D
P
N
T
I
L
Q
T
Q
D
H
Site 56
S875
L
Q
T
Q
D
H
L
S
Q
D
Y
E
S
L
R
Site 57
Y878
Q
D
H
L
S
Q
D
Y
E
S
L
R
A
L
A
Site 58
S880
H
L
S
Q
D
Y
E
S
L
R
A
L
A
Q
L
Site 59
T916
Q
L
W
L
E
K
Q
T
V
L
L
Q
R
V
Q
Site 60
T928
R
V
Q
P
Q
A
D
T
L
E
V
M
Q
L
K
Site 61
Y936
L
E
V
M
Q
L
K
Y
E
N
F
L
T
A
L
Site 62
S954
K
G
L
W
A
E
V
S
S
S
A
E
Q
L
R
Site 63
S956
L
W
A
E
V
S
S
S
A
E
Q
L
R
Q
R
Site 64
Y964
A
E
Q
L
R
Q
R
Y
P
G
N
S
T
Q
I
Site 65
S968
R
Q
R
Y
P
G
N
S
T
Q
I
Q
R
Q
Q
Site 66
T969
Q
R
Y
P
G
N
S
T
Q
I
Q
R
Q
Q
E
Site 67
S979
Q
R
Q
Q
E
E
L
S
Q
R
W
G
Q
L
E
Site 68
T1012
F
L
Q
E
C
G
P
T
Q
V
Q
L
R
D
V
Site 69
T1034
Q
P
G
S
S
E
D
T
R
H
A
L
Q
L
A
Site 70
T1045
L
Q
L
A
Q
K
K
T
L
V
L
E
R
R
V
Site 71
Y1067
V
K
V
E
E
P
G
Y
A
E
S
Q
P
L
Q
Site 72
S1070
E
E
P
G
Y
A
E
S
Q
P
L
Q
G
Q
V
Site 73
T1101
R
A
R
R
Q
A
E
T
Q
A
R
Q
S
F
L
Site 74
S1106
A
E
T
Q
A
R
Q
S
F
L
Q
E
S
Q
Q
Site 75
S1111
R
Q
S
F
L
Q
E
S
Q
Q
L
L
L
W
A
Site 76
S1120
Q
L
L
L
W
A
E
S
V
Q
A
Q
L
R
S
Site 77
S1127
S
V
Q
A
Q
L
R
S
K
E
V
S
V
D
V
Site 78
S1131
Q
L
R
S
K
E
V
S
V
D
V
A
S
A
Q
Site 79
S1136
E
V
S
V
D
V
A
S
A
Q
R
L
L
R
E
Site 80
S1165
L
Q
Q
L
D
A
Q
S
Q
P
M
A
A
L
D
Site 81
S1176
A
A
L
D
C
P
D
S
Q
E
V
P
N
T
L
Site 82
T1182
D
S
Q
E
V
P
N
T
L
R
V
L
G
Q
Q
Site 83
T1221
G
R
E
V
D
G
F
T
A
T
C
A
N
H
Q
Site 84
S1258
R
E
F
G
R
L
L
S
T
L
G
P
R
A
E
Site 85
T1259
E
F
G
R
L
L
S
T
L
G
P
R
A
E
A
Site 86
S1277
H
G
E
K
L
V
Q
S
Q
H
P
A
A
H
T
Site 87
T1284
S
Q
H
P
A
A
H
T
V
R
E
Q
L
Q
S
Site 88
S1291
T
V
R
E
Q
L
Q
S
I
Q
A
Q
W
T
R
Site 89
S1303
W
T
R
L
Q
G
R
S
E
Q
R
R
R
Q
L
Site 90
S1313
R
R
R
Q
L
L
A
S
L
Q
L
Q
E
W
K
Site 91
S1342
L
M
A
A
H
E
P
S
G
A
R
R
N
I
L
Site 92
T1351
A
R
R
N
I
L
Q
T
L
K
R
H
E
A
A
Site 93
S1360
K
R
H
E
A
A
E
S
E
L
L
A
T
R
R
Site 94
T1365
A
E
S
E
L
L
A
T
R
R
H
V
E
A
L
Site 95
S1381
Q
V
G
R
E
L
L
S
R
R
P
C
G
Q
E
Site 96
T1392
C
G
Q
E
D
I
Q
T
R
L
Q
G
L
R
S
Site 97
S1399
T
R
L
Q
G
L
R
S
K
W
E
A
L
N
R
Site 98
T1409
E
A
L
N
R
K
M
T
E
R
G
D
E
L
Q
Site 99
S1444
Q
L
E
G
A
L
Q
S
S
E
T
G
Q
D
L
Site 100
S1445
L
E
G
A
L
Q
S
S
E
T
G
Q
D
L
R
Site 101
T1447
G
A
L
Q
S
S
E
T
G
Q
D
L
R
S
S
Site 102
S1453
E
T
G
Q
D
L
R
S
S
Q
R
L
Q
K
R
Site 103
S1454
T
G
Q
D
L
R
S
S
Q
R
L
Q
K
R
H
Site 104
S1466
K
R
H
Q
Q
L
E
S
E
S
R
T
L
A
A
Site 105
T1470
Q
L
E
S
E
S
R
T
L
A
A
K
M
A
A
Site 106
S1480
A
K
M
A
A
L
A
S
M
A
H
G
M
A
A
Site 107
S1488
M
A
H
G
M
A
A
S
P
A
I
L
E
E
T
Site 108
S1519
R
G
L
Q
L
Q
A
S
V
E
L
H
Q
F
C
Site 109
S1544
A
E
H
M
P
H
G
S
P
T
S
Y
T
E
C
Site 110
S1547
M
P
H
G
S
P
T
S
Y
T
E
C
L
N
G
Site 111
Y1548
P
H
G
S
P
T
S
Y
T
E
C
L
N
G
A
Site 112
T1549
H
G
S
P
T
S
Y
T
E
C
L
N
G
A
Q
Site 113
S1557
E
C
L
N
G
A
Q
S
L
H
R
K
H
K
E
Site 114
S1581
G
Q
V
Q
R
V
L
S
S
G
R
S
L
A
A
Site 115
S1582
Q
V
Q
R
V
L
S
S
G
R
S
L
A
A
S
Site 116
S1585
R
V
L
S
S
G
R
S
L
A
A
S
G
H
P
Site 117
S1589
S
G
R
S
L
A
A
S
G
H
P
Q
A
Q
H
Site 118
S1636
Q
Q
Y
F
L
D
V
S
E
L
E
G
W
V
E
Site 119
S1650
E
E
K
R
P
L
V
S
S
R
D
Y
G
R
D
Site 120
S1651
E
K
R
P
L
V
S
S
R
D
Y
G
R
D
E
Site 121
Y1654
P
L
V
S
S
R
D
Y
G
R
D
E
A
A
T
Site 122
T1661
Y
G
R
D
E
A
A
T
L
R
L
I
N
K
H
Site 123
Y1678
L
Q
E
E
L
A
I
Y
W
S
S
M
E
E
L
Site 124
S1680
E
E
L
A
I
Y
W
S
S
M
E
E
L
D
Q
Site 125
S1681
E
L
A
I
Y
W
S
S
M
E
E
L
D
Q
T
Site 126
T1688
S
M
E
E
L
D
Q
T
A
Q
T
L
T
G
P
Site 127
T1721
A
L
Q
E
L
A
A
T
R
D
R
E
L
E
G
Site 128
T1729
R
D
R
E
L
E
G
T
L
R
L
H
E
F
L
Site 129
S1758
Q
A
A
K
G
G
E
S
L
G
E
D
P
E
H
Site 130
S1784
Q
H
Q
V
E
M
G
S
Q
R
V
A
A
C
R
Site 131
S1796
A
C
R
L
L
A
E
S
L
L
E
R
G
H
S
Site 132
S1803
S
L
L
E
R
G
H
S
A
G
P
M
V
R
Q
Site 133
T1817
Q
R
Q
Q
D
L
Q
T
A
W
S
E
L
W
E
Site 134
S1820
Q
D
L
Q
T
A
W
S
E
L
W
E
L
T
Q
Site 135
T1826
W
S
E
L
W
E
L
T
Q
A
R
G
H
A
L
Site 136
T1836
R
G
H
A
L
R
D
T
E
T
T
L
R
V
H
Site 137
T1838
H
A
L
R
D
T
E
T
T
L
R
V
H
R
D
Site 138
T1839
A
L
R
D
T
E
T
T
L
R
V
H
R
D
L
Site 139
T1851
R
D
L
L
E
V
L
T
Q
V
Q
E
K
A
T
Site 140
S1859
Q
V
Q
E
K
A
T
S
L
P
N
N
V
A
R
Site 141
T1888
L
E
R
E
L
V
G
T
E
R
Q
L
Q
E
L
Site 142
T1898
Q
L
Q
E
L
L
E
T
A
G
R
V
Q
K
L
Site 143
T1922
Q
Q
R
Q
Q
A
V
T
Q
A
W
A
V
L
Q
Site 144
T1950
R
L
L
A
R
F
R
T
A
V
R
D
Y
A
S
Site 145
Y1955
F
R
T
A
V
R
D
Y
A
S
W
A
A
R
V
Site 146
S1971
Q
D
L
Q
V
E
E
S
S
Q
E
P
S
S
G
Site 147
S1972
D
L
Q
V
E
E
S
S
Q
E
P
S
S
G
P
Site 148
S1976
E
E
S
S
Q
E
P
S
S
G
P
L
K
L
S
Site 149
S1977
E
S
S
Q
E
P
S
S
G
P
L
K
L
S
A
Site 150
S1983
S
S
G
P
L
K
L
S
A
H
Q
W
L
R
A
Site 151
T2015
Q
A
L
L
A
A
G
T
P
T
K
E
V
Q
E
Site 152
Y2035
Q
D
Q
R
D
Q
V
Y
Q
T
W
A
R
K
Q
Site 153
T2037
Q
R
D
Q
V
Y
Q
T
W
A
R
K
Q
E
R
Site 154
S2075
Q
E
V
S
L
K
T
S
A
L
G
S
S
V
E
Site 155
S2079
L
K
T
S
A
L
G
S
S
V
E
E
V
E
Q
Site 156
S2080
K
T
S
A
L
G
S
S
V
E
E
V
E
Q
L
Site 157
T2114
A
L
R
E
R
L
K
T
L
R
R
P
R
V
R
Site 158
S2140
R
V
K
E
L
A
E
S
R
G
H
A
L
H
A
Site 159
T2206
Q
A
H
E
E
V
M
T
S
V
A
K
K
G
E
Site 160
S2207
A
H
E
E
V
M
T
S
V
A
K
K
G
E
A
Site 161
S2219
G
E
A
L
L
A
Q
S
H
P
R
A
G
E
V
Site 162
S2227
H
P
R
A
G
E
V
S
Q
R
L
Q
G
L
R
Site 163
S2304
L
R
E
F
R
G
N
S
A
G
D
T
V
G
D
Site 164
T2308
R
G
N
S
A
G
D
T
V
G
D
A
C
I
R
Site 165
S2321
I
R
S
I
S
D
L
S
L
Q
L
K
N
R
D
Site 166
S2348
Q
L
N
N
R
W
A
S
F
H
G
N
L
L
R
Site 167
Y2356
F
H
G
N
L
L
R
Y
Q
Q
Q
L
E
G
A
Site 168
T2377
S
R
E
L
D
N
V
T
K
R
I
Q
E
K
E
Site 169
S2398
D
C
G
K
D
L
E
S
V
Q
R
L
L
R
K
Site 170
S2422
P
I
Q
A
Q
V
E
S
L
E
R
E
V
G
R
Site 171
S2434
V
G
R
L
C
Q
R
S
P
E
A
A
H
G
L
Site 172
S2451
R
Q
Q
E
V
A
E
S
W
W
Q
L
R
S
R
Site 173
S2485
M
L
Q
E
L
L
V
S
A
Q
R
L
R
A
Q
Site 174
T2495
R
L
R
A
Q
M
D
T
S
P
A
P
R
S
P
Site 175
S2496
L
R
A
Q
M
D
T
S
P
A
P
R
S
P
V
Site 176
S2501
D
T
S
P
A
P
R
S
P
V
E
A
R
R
M
Site 177
S2521
E
C
K
A
E
L
D
S
W
T
D
S
I
S
L
Site 178
T2523
K
A
E
L
D
S
W
T
D
S
I
S
L
A
R
Site 179
S2525
E
L
D
S
W
T
D
S
I
S
L
A
R
S
T
Site 180
S2527
D
S
W
T
D
S
I
S
L
A
R
S
T
G
Q
Site 181
S2531
D
S
I
S
L
A
R
S
T
G
Q
Q
L
L
T
Site 182
T2538
S
T
G
Q
Q
L
L
T
A
G
H
P
F
S
S
Site 183
S2544
L
T
A
G
H
P
F
S
S
D
I
R
Q
V
L
Site 184
S2545
T
A
G
H
P
F
S
S
D
I
R
Q
V
L
A
Site 185
S2559
A
G
L
E
Q
E
L
S
S
L
E
G
A
W
Q
Site 186
S2583
L
E
L
Q
L
F
L
S
S
V
E
K
M
E
R
Site 187
S2584
E
L
Q
L
F
L
S
S
V
E
K
M
E
R
W
Site 188
S2594
K
M
E
R
W
L
C
S
K
E
D
S
L
A
S
Site 189
S2598
W
L
C
S
K
E
D
S
L
A
S
E
G
L
W
Site 190
S2652
G
G
H
P
E
A
Q
S
A
L
G
R
C
Q
A
Site 191
S2733
F
Q
A
E
L
D
A
S
M
H
Q
Q
Q
E
L
Site 192
S2755
L
Q
G
G
H
P
A
S
E
A
I
Q
E
R
L
Site 193
S2776
W
G
E
L
Q
D
N
S
Q
K
K
V
A
K
L
Site 194
S2795
E
A
L
R
L
R
R
S
M
E
E
L
E
N
W
Site 195
T2814
E
V
E
L
R
A
P
T
V
G
Q
A
L
P
G
Site 196
T2828
G
V
G
E
L
L
G
T
Q
R
E
L
E
A
A
Site 197
S2877
R
L
L
Q
R
F
K
S
L
R
E
P
L
Q
E
Site 198
T2887
E
P
L
Q
E
R
R
T
A
L
E
A
R
S
L
Site 199
S2924
A
A
Q
D
Y
G
Q
S
L
S
A
V
R
H
L
Site 200
S2926
Q
D
Y
G
Q
S
L
S
A
V
R
H
L
Q
E
Site 201
S2940
E
Q
H
Q
N
L
E
S
E
M
S
S
H
E
A
Site 202
S2943
Q
N
L
E
S
E
M
S
S
H
E
A
L
T
R
Site 203
S2944
N
L
E
S
E
M
S
S
H
E
A
L
T
R
V
Site 204
S3013
T
E
L
L
E
A
G
S
W
L
A
E
R
G
H
Site 205
S3024
E
R
G
H
V
L
D
S
E
D
M
G
H
S
A
Site 206
T3034
M
G
H
S
A
E
A
T
Q
A
L
L
R
R
L
Site 207
T3044
L
L
R
R
L
E
A
T
K
R
D
L
E
A
F
Site 208
S3052
K
R
D
L
E
A
F
S
P
R
I
E
R
L
Q
Site 209
S3073
E
S
R
K
N
P
E
S
P
K
V
L
A
Q
L
Site 210
Y3133
A
T
A
E
S
Q
D
Y
G
Q
D
L
E
G
V
Site 211
S3156
A
F
R
K
E
V
Q
S
L
G
Q
A
K
V
Y
Site 212
T3171
A
L
R
K
L
A
G
T
L
E
R
G
A
P
R
Site 213
Y3180
E
R
G
A
P
R
R
Y
P
H
I
Q
A
Q
R
Site 214
S3216
A
A
A
H
E
V
H
S
F
Q
Q
A
A
A
E
Site 215
T3232
Q
G
R
M
Q
E
K
T
A
L
M
K
G
E
D
Site 216
S3243
K
G
E
D
G
G
H
S
L
S
S
V
R
T
L
Site 217
S3245
E
D
G
G
H
S
L
S
S
V
R
T
L
Q
Q
Site 218
S3246
D
G
G
H
S
L
S
S
V
R
T
L
Q
Q
Q
Site 219
T3249
H
S
L
S
S
V
R
T
L
Q
Q
Q
H
R
R
Site 220
T3273
K
E
V
A
R
L
Q
T
E
A
C
R
L
G
Q
Site 221
T3298
K
V
Q
E
A
W
A
T
L
Q
A
K
A
Q
E
Site 222
S3338
Q
E
R
Q
E
L
A
S
S
E
E
L
A
E
D
Site 223
S3339
E
R
Q
E
L
A
S
S
E
E
L
A
E
D
V
Site 224
S3384
G
Q
Q
L
V
D
N
S
H
F
M
S
A
E
V
Site 225
S3388
V
D
N
S
H
F
M
S
A
E
V
T
E
C
L
Site 226
T3392
H
F
M
S
A
E
V
T
E
C
L
Q
E
L
E
Site 227
Y3448
G
L
L
L
K
P
D
Y
G
H
S
V
S
D
V
Site 228
S3451
L
K
P
D
Y
G
H
S
V
S
D
V
E
L
L
Site 229
S3453
P
D
Y
G
H
S
V
S
D
V
E
L
L
L
H
Site 230
S3502
L
K
P
G
R
A
G
S
S
L
T
S
F
Q
W
Site 231
S3503
K
P
G
R
A
G
S
S
L
T
S
F
Q
W
R
Site 232
S3506
R
A
G
S
S
L
T
S
F
Q
W
R
P
S
G
Site 233
S3512
T
S
F
Q
W
R
P
S
G
H
Q
G
L
G
A
Site 234
T3524
L
G
A
Q
L
A
E
T
R
D
P
Q
D
A
K
Site 235
T3533
D
P
Q
D
A
K
G
T
P
T
M
E
G
S
L
Site 236
T3535
Q
D
A
K
G
T
P
T
M
E
G
S
L
E
F
Site 237
S3539
G
T
P
T
M
E
G
S
L
E
F
K
Q
H
L
Site 238
S3554
L
P
G
G
R
Q
P
S
S
S
S
W
D
S
C
Site 239
S3555
P
G
G
R
Q
P
S
S
S
S
W
D
S
C
R
Site 240
S3556
G
G
R
Q
P
S
S
S
S
W
D
S
C
R
G
Site 241
S3557
G
R
Q
P
S
S
S
S
W
D
S
C
R
G
T
Site 242
S3560
P
S
S
S
S
W
D
S
C
R
G
T
L
Q
G
Site 243
T3564
S
W
D
S
C
R
G
T
L
Q
G
S
S
L
S
Site 244
S3569
R
G
T
L
Q
G
S
S
L
S
L
F
L
D
E
Site 245
S3571
T
L
Q
G
S
S
L
S
L
F
L
D
E
R
M
Site 246
T3608
G
R
H
G
R
K
H
T
F
S
L
R
L
T
S
Site 247
S3610
H
G
R
K
H
T
F
S
L
R
L
T
S
G
A
Site 248
S3625
E
I
L
F
A
A
P
S
E
E
Q
A
E
S
W
Site 249
S3631
P
S
E
E
Q
A
E
S
W
W
R
A
L
G
S
Site 250
S3638
S
W
W
R
A
L
G
S
T
A
A
Q
S
L
S
Site 251
T3639
W
W
R
A
L
G
S
T
A
A
Q
S
L
S
P
Site 252
S3643
L
G
S
T
A
A
Q
S
L
S
P
K
L
K
A
Site 253
S3645
S
T
A
A
Q
S
L
S
P
K
L
K
A
K
P
Site 254
S3655
L
K
A
K
P
V
S
S
L
N
E
C
T
T
K
Site 255
T3661
S
S
L
N
E
C
T
T
K
D
A
R
P
G
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation