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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ENTPD7
Full Name:
Ectonucleoside triphosphate diphosphohydrolase 7
Alias:
Lysosomal apyrase-like protein 1
Type:
Mass (Da):
68960
Number AA:
604
UniProt ID:
Q9NQZ7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
S
W
Y
F
T
V
P
T
V
S
P
F
L
R
Q
Site 2
S53
I
I
D
F
R
H
W
S
A
S
L
P
R
D
R
Site 3
S55
D
F
R
H
W
S
A
S
L
P
R
D
R
Q
Y
Site 4
Y62
S
L
P
R
D
R
Q
Y
E
R
Y
L
A
R
V
Site 5
Y65
R
D
R
Q
Y
E
R
Y
L
A
R
V
G
E
L
Site 6
T75
R
V
G
E
L
E
A
T
D
T
E
D
P
N
L
Site 7
T77
G
E
L
E
A
T
D
T
E
D
P
N
L
N
Y
Site 8
Y84
T
E
D
P
N
L
N
Y
G
L
V
V
D
C
G
Site 9
Y100
S
G
S
R
I
F
V
Y
F
W
P
R
H
N
G
Site 10
S123
K
Q
M
R
D
R
N
S
Q
P
V
V
K
K
I
Site 11
T140
G
I
S
A
M
A
D
T
P
E
H
A
S
D
Y
Site 12
Y147
T
P
E
H
A
S
D
Y
L
R
P
L
L
S
F
Site 13
T167
P
V
K
K
H
K
E
T
P
L
Y
I
L
C
T
Site 14
Y170
K
H
K
E
T
P
L
Y
I
L
C
T
A
G
M
Site 15
T174
T
P
L
Y
I
L
C
T
A
G
M
R
L
L
P
Site 16
Y220
S
G
K
Q
E
G
V
Y
A
W
I
G
I
N
F
Site 17
S238
R
F
D
H
E
D
E
S
D
A
E
A
T
Q
E
Site 18
T253
L
A
A
G
R
R
R
T
V
G
I
L
D
M
G
Site 19
S263
I
L
D
M
G
G
A
S
L
Q
I
A
Y
E
V
Site 20
Y268
G
A
S
L
Q
I
A
Y
E
V
P
T
S
T
S
Site 21
S275
Y
E
V
P
T
S
T
S
V
L
P
A
K
Q
E
Site 22
Y324
G
N
F
A
R
Q
R
Y
E
D
L
V
L
N
E
Site 23
T332
E
D
L
V
L
N
E
T
L
N
K
N
R
L
L
Site 24
T343
N
R
L
L
G
Q
K
T
G
L
S
P
D
N
P
Site 25
S346
L
G
Q
K
T
G
L
S
P
D
N
P
F
L
D
Site 26
S368
T
D
V
V
E
R
N
S
Q
V
L
H
V
R
G
Site 27
S381
R
G
R
G
D
W
V
S
C
G
A
M
L
S
P
Site 28
S393
L
S
P
L
L
A
R
S
N
T
S
Q
A
S
L
Site 29
T395
P
L
L
A
R
S
N
T
S
Q
A
S
L
N
G
Site 30
S399
R
S
N
T
S
Q
A
S
L
N
G
I
Y
Q
S
Site 31
Y404
Q
A
S
L
N
G
I
Y
Q
S
P
I
D
F
N
Site 32
S406
S
L
N
G
I
Y
Q
S
P
I
D
F
N
N
S
Site 33
S413
S
P
I
D
F
N
N
S
E
F
Y
G
F
S
E
Site 34
Y423
Y
G
F
S
E
F
F
Y
C
T
E
D
V
L
R
Site 35
Y435
V
L
R
I
G
G
R
Y
H
G
P
T
F
A
K
Site 36
T439
G
G
R
Y
H
G
P
T
F
A
K
A
A
Q
D
Site 37
T456
G
M
A
W
S
V
L
T
Q
R
F
K
N
G
L
Site 38
S465
R
F
K
N
G
L
F
S
S
H
A
D
E
H
R
Site 39
S466
F
K
N
G
L
F
S
S
H
A
D
E
H
R
L
Site 40
Y475
A
D
E
H
R
L
K
Y
Q
C
F
K
S
A
W
Site 41
Y495
H
E
G
F
H
F
P
Y
D
Y
P
N
L
R
T
Site 42
Y497
G
F
H
F
P
Y
D
Y
P
N
L
R
T
A
Q
Site 43
Y507
L
R
T
A
Q
L
V
Y
D
R
E
V
Q
W
T
Site 44
T514
Y
D
R
E
V
Q
W
T
L
G
A
I
L
Y
K
Site 45
S541
G
V
R
Q
A
H
G
S
W
F
R
L
S
F
V
Site 46
T580
R
R
I
H
H
R
Q
T
R
A
S
A
P
L
D
Site 47
S583
H
H
R
Q
T
R
A
S
A
P
L
D
L
L
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation