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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRDM7
Full Name:
Probable histone-lysine N-methyltransferase PRDM7
Alias:
PR domain zinc finger protein 7;PR domain-containing protein 7
Type:
Mass (Da):
55777
Number AA:
492
UniProt ID:
Q9NQW5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
P
E
R
S
Q
E
E
S
P
E
G
Site 2
S10
P
E
R
S
Q
E
E
S
P
E
G
D
T
E
R
Site 3
T15
E
E
S
P
E
G
D
T
E
R
T
E
R
K
P
Site 4
T18
P
E
G
D
T
E
R
T
E
R
K
P
M
V
K
Site 5
S32
K
D
A
F
K
D
I
S
I
Y
F
T
K
E
E
Site 6
Y34
A
F
K
D
I
S
I
Y
F
T
K
E
E
W
A
Site 7
T36
K
D
I
S
I
Y
F
T
K
E
E
W
A
E
M
Site 8
Y51
G
D
W
E
K
T
R
Y
R
N
V
K
M
N
Y
Site 9
T69
I
T
V
G
L
R
A
T
R
P
A
F
M
C
H
Site 10
T88
I
K
L
Q
V
D
D
T
E
D
S
D
E
E
W
Site 11
S91
Q
V
D
D
T
E
D
S
D
E
E
W
T
P
R
Site 12
T96
E
D
S
D
E
E
W
T
P
R
Q
Q
V
K
P
Site 13
S123
Q
K
G
M
P
K
A
S
F
N
N
E
S
S
L
Site 14
S128
K
A
S
F
N
N
E
S
S
L
R
E
L
S
G
Site 15
S129
A
S
F
N
N
E
S
S
L
R
E
L
S
G
T
Site 16
S134
E
S
S
L
R
E
L
S
G
T
P
N
L
L
N
Site 17
T136
S
L
R
E
L
S
G
T
P
N
L
L
N
T
S
Site 18
S143
T
P
N
L
L
N
T
S
D
S
E
Q
A
Q
K
Site 19
S145
N
L
L
N
T
S
D
S
E
Q
A
Q
K
P
V
Site 20
S153
E
Q
A
Q
K
P
V
S
P
P
G
E
A
S
T
Site 21
S159
V
S
P
P
G
E
A
S
T
S
G
Q
H
S
R
Site 22
S161
P
P
G
E
A
S
T
S
G
Q
H
S
R
L
K
Site 23
S165
A
S
T
S
G
Q
H
S
R
L
K
L
E
L
R
Site 24
T176
L
E
L
R
R
K
E
T
E
G
K
M
Y
S
L
Site 25
Y181
K
E
T
E
G
K
M
Y
S
L
R
E
R
K
G
Site 26
S182
E
T
E
G
K
M
Y
S
L
R
E
R
K
G
H
Site 27
Y191
R
E
R
K
G
H
A
Y
K
E
I
S
E
P
Q
Site 28
S195
G
H
A
Y
K
E
I
S
E
P
Q
D
D
D
Y
Site 29
Y202
S
E
P
Q
D
D
D
Y
L
Y
C
E
M
C
Q
Site 30
Y204
P
Q
D
D
D
Y
L
Y
C
E
M
C
Q
N
F
Site 31
S228
P
P
T
F
V
K
D
S
A
V
D
K
G
H
P
Site 32
S238
D
K
G
H
P
N
R
S
A
L
S
L
P
P
G
Site 33
S241
H
P
N
R
S
A
L
S
L
P
P
G
L
R
I
Site 34
Y276
L
G
L
H
F
G
P
Y
E
G
R
I
T
E
D
Site 35
T281
G
P
Y
E
G
R
I
T
E
D
E
E
A
A
N
Site 36
S289
E
D
E
E
A
A
N
S
G
Y
S
W
L
I
T
Site 37
Y302
I
T
K
G
R
N
C
Y
E
Y
V
D
G
K
D
Site 38
Y304
K
G
R
N
C
Y
E
Y
V
D
G
K
D
K
S
Site 39
Y318
S
S
A
N
W
M
R
Y
V
N
C
A
R
D
D
Site 40
Y335
Q
N
L
V
A
F
Q
Y
H
R
Q
I
F
Y
R
Site 41
S357
G
C
E
L
L
V
W
S
G
D
E
Y
G
Q
E
Site 42
Y361
L
V
W
S
G
D
E
Y
G
Q
E
L
G
I
R
Site 43
S370
Q
E
L
G
I
R
S
S
I
E
P
A
E
S
L
Site 44
S376
S
S
I
E
P
A
E
S
L
G
Q
A
V
N
C
Site 45
S397
S
M
A
R
N
W
A
S
S
G
A
A
S
G
R
Site 46
S398
M
A
R
N
W
A
S
S
G
A
A
S
G
R
K
Site 47
S402
W
A
S
S
G
A
A
S
G
R
K
S
S
W
Q
Site 48
S406
G
A
A
S
G
R
K
S
S
W
Q
G
E
N
Q
Site 49
S407
A
A
S
G
R
K
S
S
W
Q
G
E
N
Q
S
Site 50
S414
S
W
Q
G
E
N
Q
S
Q
R
S
I
H
V
P
Site 51
T441
V
N
M
W
N
A
I
T
P
L
R
T
S
Q
D
Site 52
S446
A
I
T
P
L
R
T
S
Q
D
H
L
Q
E
N
Site 53
S455
D
H
L
Q
E
N
F
S
N
Q
R
I
P
A
Q
Site 54
S486
T
K
P
K
V
K
R
S
K
K
G
P
N
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation