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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRDM10
Full Name:
PR domain zinc finger protein 10
Alias:
PR domain containing 10
Type:
Mass (Da):
130108
Number AA:
1147
UniProt ID:
Q9NQV6
International Prot ID:
IPI00398772
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0044464
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0008270
GO:0043167
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
D
S
K
D
E
S
S
H
V
W
P
T
S
Site 2
S8
M
D
S
K
D
E
S
S
H
V
W
P
T
S
A
Site 3
S14
S
S
H
V
W
P
T
S
A
E
H
E
Q
N
A
Site 4
S46
T
D
D
Q
V
R
P
S
Q
Q
V
V
Y
T
A
Site 5
Y51
R
P
S
Q
Q
V
V
Y
T
A
D
G
A
S
Y
Site 6
Y58
Y
T
A
D
G
A
S
Y
T
S
V
D
G
P
E
Site 7
S60
A
D
G
A
S
Y
T
S
V
D
G
P
E
H
T
Site 8
T79
H
P
V
E
A
A
Q
T
L
F
T
D
P
G
Q
Site 9
Y89
T
D
P
G
Q
V
A
Y
V
Q
Q
D
A
T
A
Site 10
S110
V
H
N
Q
V
L
P
S
I
E
S
V
D
G
S
Site 11
S113
Q
V
L
P
S
I
E
S
V
D
G
S
D
P
L
Site 12
S117
S
I
E
S
V
D
G
S
D
P
L
A
T
L
Q
Site 13
T122
D
G
S
D
P
L
A
T
L
Q
T
P
L
G
R
Site 14
T125
D
P
L
A
T
L
Q
T
P
L
G
R
L
E
A
Site 15
T144
D
E
D
E
D
E
D
T
E
E
D
E
E
E
D
Site 16
S223
R
F
L
G
G
V
F
S
K
R
R
I
P
K
R
Site 17
T231
K
R
R
I
P
K
R
T
Q
F
G
P
V
E
G
Site 18
S244
E
G
P
L
V
R
G
S
E
L
K
D
C
Y
I
Site 19
Y250
G
S
E
L
K
D
C
Y
I
H
L
K
V
S
L
Site 20
Y301
L
E
Q
N
L
V
A
Y
Q
Y
G
H
H
V
Y
Site 21
Y309
Q
Y
G
H
H
V
Y
Y
T
T
I
K
N
V
E
Site 22
S341
N
Q
K
I
H
D
I
S
E
E
E
R
K
V
L
Site 23
S366
E
C
N
R
R
F
I
S
S
E
Q
L
Q
Q
H
Site 24
S367
C
N
R
R
F
I
S
S
E
Q
L
Q
Q
H
L
Site 25
S376
Q
L
Q
Q
H
L
N
S
H
D
E
K
L
D
V
Site 26
S385
D
E
K
L
D
V
F
S
R
T
R
G
R
G
R
Site 27
S418
F
I
R
L
E
I
T
S
E
N
G
E
K
S
D
Site 28
S424
T
S
E
N
G
E
K
S
D
D
G
T
Q
D
L
Site 29
T428
G
E
K
S
D
D
G
T
Q
D
L
L
H
F
P
Site 30
T457
G
L
D
Q
P
E
Q
T
T
I
P
I
P
Q
L
Site 31
S471
L
P
Q
E
T
Q
S
S
L
E
H
E
P
E
T
Site 32
S490
L
Q
P
Q
H
E
E
S
V
V
P
T
Q
S
T
Site 33
T494
H
E
E
S
V
V
P
T
Q
S
T
L
T
A
D
Site 34
S571
L
C
N
K
G
F
I
S
S
T
S
L
E
S
H
Site 35
S572
C
N
K
G
F
I
S
S
T
S
L
E
S
H
M
Site 36
T573
N
K
G
F
I
S
S
T
S
L
E
S
H
M
K
Site 37
S574
K
G
F
I
S
S
T
S
L
E
S
H
M
K
L
Site 38
S577
I
S
S
T
S
L
E
S
H
M
K
L
H
S
D
Site 39
S583
E
S
H
M
K
L
H
S
D
Q
K
T
Y
S
C
Site 40
T587
K
L
H
S
D
Q
K
T
Y
S
C
I
F
C
P
Site 41
S637
Q
V
K
K
H
V
R
S
F
H
S
E
K
I
Y
Site 42
Y644
S
F
H
S
E
K
I
Y
Q
C
T
E
C
D
K
Site 43
S667
R
L
H
M
L
R
H
S
D
R
K
D
F
L
C
Site 44
S708
A
K
K
A
D
R
I
S
R
S
K
T
F
K
P
Site 45
S710
K
A
D
R
I
S
R
S
K
T
F
K
P
R
I
Site 46
T712
D
R
I
S
R
S
K
T
F
K
P
R
I
T
S
Site 47
T718
K
T
F
K
P
R
I
T
S
T
D
Y
D
S
F
Site 48
S719
T
F
K
P
R
I
T
S
T
D
Y
D
S
F
T
Site 49
T720
F
K
P
R
I
T
S
T
D
Y
D
S
F
T
F
Site 50
Y722
P
R
I
T
S
T
D
Y
D
S
F
T
F
K
C
Site 51
S724
I
T
S
T
D
Y
D
S
F
T
F
K
C
R
L
Site 52
S747
G
M
L
V
N
H
L
S
K
R
H
P
D
M
K
Site 53
Y772
I
I
K
P
N
R
D
Y
F
C
Q
Y
C
D
K
Site 54
Y776
N
R
D
Y
F
C
Q
Y
C
D
K
V
Y
K
S
Site 55
Y781
C
Q
Y
C
D
K
V
Y
K
S
A
S
K
R
K
Site 56
S783
Y
C
D
K
V
Y
K
S
A
S
K
R
K
A
H
Site 57
S785
D
K
V
Y
K
S
A
S
K
R
K
A
H
I
L
Site 58
S803
P
G
A
E
L
P
P
S
I
R
K
L
R
P
A
Site 59
S820
G
E
P
D
P
M
L
S
T
H
T
Q
L
T
G
Site 60
S844
P
H
C
S
K
Q
Y
S
S
K
T
K
M
V
Q
Site 61
T847
S
K
Q
Y
S
S
K
T
K
M
V
Q
H
I
R
Site 62
S864
H
P
E
F
A
Q
L
S
N
T
I
H
T
P
L
Site 63
S907
T
Q
A
M
T
E
L
S
Q
T
L
T
T
D
Y
Site 64
T909
A
M
T
E
L
S
Q
T
L
T
T
D
Y
R
T
Site 65
T911
T
E
L
S
Q
T
L
T
T
D
Y
R
T
P
Q
Site 66
T912
E
L
S
Q
T
L
T
T
D
Y
R
T
P
Q
G
Site 67
Y914
S
Q
T
L
T
T
D
Y
R
T
P
Q
G
D
Y
Site 68
T916
T
L
T
T
D
Y
R
T
P
Q
G
D
Y
Q
R
Site 69
Y921
Y
R
T
P
Q
G
D
Y
Q
R
I
Q
Y
I
P
Site 70
Y926
G
D
Y
Q
R
I
Q
Y
I
P
V
S
Q
S
A
Site 71
S930
R
I
Q
Y
I
P
V
S
Q
S
A
S
G
L
Q
Site 72
S932
Q
Y
I
P
V
S
Q
S
A
S
G
L
Q
Q
P
Site 73
S934
I
P
V
S
Q
S
A
S
G
L
Q
Q
P
Q
H
Site 74
S954
V
Q
V
A
S
A
T
S
P
H
Q
S
Q
Q
S
Site 75
S958
S
A
T
S
P
H
Q
S
Q
Q
S
T
V
D
V
Site 76
T962
P
H
Q
S
Q
Q
S
T
V
D
V
G
Q
L
H
Site 77
S987
Q
V
Q
H
I
Q
V
S
G
Q
P
L
S
P
S
Site 78
S992
Q
V
S
G
Q
P
L
S
P
S
A
Q
Q
A
Q
Site 79
S994
S
G
Q
P
L
S
P
S
A
Q
Q
A
Q
Q
G
Site 80
S1003
Q
Q
A
Q
Q
G
L
S
P
S
H
I
Q
G
S
Site 81
S1005
A
Q
Q
G
L
S
P
S
H
I
Q
G
S
S
S
Site 82
S1010
S
P
S
H
I
Q
G
S
S
S
T
Q
G
Q
A
Site 83
S1012
S
H
I
Q
G
S
S
S
T
Q
G
Q
A
L
Q
Site 84
S1029
Q
Q
Q
Q
Q
N
S
S
V
Q
H
T
Y
L
P
Site 85
T1033
Q
N
S
S
V
Q
H
T
Y
L
P
S
A
W
N
Site 86
Y1034
N
S
S
V
Q
H
T
Y
L
P
S
A
W
N
S
Site 87
S1041
Y
L
P
S
A
W
N
S
F
R
G
Y
S
S
E
Site 88
Y1045
A
W
N
S
F
R
G
Y
S
S
E
I
Q
M
M
Site 89
Y1083
K
A
V
T
S
G
H
Y
V
L
S
E
S
Q
S
Site 90
S1086
T
S
G
H
Y
V
L
S
E
S
Q
S
E
L
E
Site 91
S1088
G
H
Y
V
L
S
E
S
Q
S
E
L
E
E
K
Site 92
S1090
Y
V
L
S
E
S
Q
S
E
L
E
E
K
Q
T
Site 93
T1097
S
E
L
E
E
K
Q
T
S
A
L
S
G
G
V
Site 94
S1098
E
L
E
E
K
Q
T
S
A
L
S
G
G
V
Q
Site 95
S1112
Q
V
E
P
P
A
H
S
D
S
L
D
P
Q
T
Site 96
S1114
E
P
P
A
H
S
D
S
L
D
P
Q
T
N
S
Site 97
T1119
S
D
S
L
D
P
Q
T
N
S
Q
Q
Q
T
T
Site 98
S1121
S
L
D
P
Q
T
N
S
Q
Q
Q
T
T
Q
Y
Site 99
Y1128
S
Q
Q
Q
T
T
Q
Y
I
I
T
T
T
T
N
Site 100
S1140
T
T
N
G
N
G
S
S
E
V
H
I
T
K
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation