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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DMRT3
Full Name:
Doublesex- and mab-3-related transcription factor 3
Alias:
DMRTA3; Doublesex and mab-3 related transcription factor 3; Doublesex and mab-3-related transcription factor 3
Type:
Mass (Da):
51199
Number AA:
472
UniProt ID:
Q9NQL9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007275
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
N
G
Y
G
S
P
Y
L
Y
M
G
G
P
V
Site 2
Y10
G
Y
G
S
P
Y
L
Y
M
G
G
P
V
S
Q
Site 3
S16
L
Y
M
G
G
P
V
S
Q
P
P
R
A
P
L
Site 4
T26
P
R
A
P
L
Q
R
T
P
K
C
A
R
C
R
Site 5
S82
R
R
Q
Q
A
N
E
S
L
E
S
L
I
P
D
Site 6
S85
Q
A
N
E
S
L
E
S
L
I
P
D
S
L
R
Site 7
S113
A
P
Q
P
P
P
A
S
Q
P
S
Q
P
Q
P
Site 8
S116
P
P
P
A
S
Q
P
S
Q
P
Q
P
P
R
P
Site 9
T136
A
A
A
A
L
R
W
T
A
E
P
Q
P
G
A
Site 10
T154
Q
L
A
K
P
D
L
T
E
E
R
L
G
D
G
Site 11
S163
E
R
L
G
D
G
K
S
A
D
N
T
E
V
F
Site 12
T167
D
G
K
S
A
D
N
T
E
V
F
S
D
K
D
Site 13
T175
E
V
F
S
D
K
D
T
D
Q
R
S
S
P
D
Site 14
S179
D
K
D
T
D
Q
R
S
S
P
D
V
A
K
S
Site 15
S180
K
D
T
D
Q
R
S
S
P
D
V
A
K
S
K
Site 16
S186
S
S
P
D
V
A
K
S
K
G
C
F
T
P
E
Site 17
T191
A
K
S
K
G
C
F
T
P
E
S
P
E
I
V
Site 18
S194
K
G
C
F
T
P
E
S
P
E
I
V
S
V
E
Site 19
S199
P
E
S
P
E
I
V
S
V
E
E
G
G
Y
A
Site 20
Y205
V
S
V
E
E
G
G
Y
A
V
Q
K
N
G
G
Site 21
S216
K
N
G
G
N
P
E
S
R
P
D
S
P
K
C
Site 22
S220
N
P
E
S
R
P
D
S
P
K
C
H
A
E
Q
Site 23
S240
E
G
P
S
G
T
V
S
L
P
F
S
L
K
A
Site 24
S244
G
T
V
S
L
P
F
S
L
K
A
N
R
P
P
Site 25
T265
I
F
P
N
Q
K
P
T
V
L
E
L
I
L
K
Site 26
S290
E
V
L
L
S
S
R
S
S
V
T
G
A
E
R
Site 27
S291
V
L
L
S
S
R
S
S
V
T
G
A
E
R
T
Site 28
S299
V
T
G
A
E
R
T
S
A
E
P
E
S
L
A
Site 29
S304
R
T
S
A
E
P
E
S
L
A
L
P
S
N
G
Site 30
T317
N
G
H
I
F
E
H
T
L
S
S
Y
P
I
S
Site 31
S319
H
I
F
E
H
T
L
S
S
Y
P
I
S
S
S
Site 32
S320
I
F
E
H
T
L
S
S
Y
P
I
S
S
S
K
Site 33
Y321
F
E
H
T
L
S
S
Y
P
I
S
S
S
K
W
Site 34
S324
T
L
S
S
Y
P
I
S
S
S
K
W
S
V
G
Site 35
S325
L
S
S
Y
P
I
S
S
S
K
W
S
V
G
S
Site 36
S326
S
S
Y
P
I
S
S
S
K
W
S
V
G
S
A
Site 37
S329
P
I
S
S
S
K
W
S
V
G
S
A
F
R
V
Site 38
S332
S
S
K
W
S
V
G
S
A
F
R
V
P
D
T
Site 39
T339
S
A
F
R
V
P
D
T
L
R
F
S
A
D
S
Site 40
S343
V
P
D
T
L
R
F
S
A
D
S
S
N
V
V
Site 41
S346
T
L
R
F
S
A
D
S
S
N
V
V
P
S
P
Site 42
S347
L
R
F
S
A
D
S
S
N
V
V
P
S
P
L
Site 43
S352
D
S
S
N
V
V
P
S
P
L
A
G
P
L
Q
Site 44
Y368
P
F
P
Q
P
P
R
Y
P
L
M
L
R
N
T
Site 45
T375
Y
P
L
M
L
R
N
T
L
A
R
S
Q
S
S
Site 46
S379
L
R
N
T
L
A
R
S
Q
S
S
P
F
L
P
Site 47
S381
N
T
L
A
R
S
Q
S
S
P
F
L
P
N
D
Site 48
S382
T
L
A
R
S
Q
S
S
P
F
L
P
N
D
V
Site 49
T390
P
F
L
P
N
D
V
T
L
W
N
T
M
T
L
Site 50
T396
V
T
L
W
N
T
M
T
L
Q
Q
Q
Y
Q
L
Site 51
Y401
T
M
T
L
Q
Q
Q
Y
Q
L
R
S
Q
Y
V
Site 52
S405
Q
Q
Q
Y
Q
L
R
S
Q
Y
V
S
P
F
P
Site 53
Y407
Q
Y
Q
L
R
S
Q
Y
V
S
P
F
P
S
N
Site 54
S409
Q
L
R
S
Q
Y
V
S
P
F
P
S
N
S
T
Site 55
S413
Q
Y
V
S
P
F
P
S
N
S
T
S
V
F
R
Site 56
S415
V
S
P
F
P
S
N
S
T
S
V
F
R
S
S
Site 57
S417
P
F
P
S
N
S
T
S
V
F
R
S
S
P
V
Site 58
S421
N
S
T
S
V
F
R
S
S
P
V
L
P
A
R
Site 59
S422
S
T
S
V
F
R
S
S
P
V
L
P
A
R
A
Site 60
T430
P
V
L
P
A
R
A
T
E
D
P
R
I
S
I
Site 61
S436
A
T
E
D
P
R
I
S
I
P
D
D
G
C
P
Site 62
T452
V
S
K
Q
S
I
Y
T
E
D
D
Y
D
E
R
Site 63
Y456
S
I
Y
T
E
D
D
Y
D
E
R
S
D
S
S
Site 64
S460
E
D
D
Y
D
E
R
S
D
S
S
D
S
R
T
Site 65
S462
D
Y
D
E
R
S
D
S
S
D
S
R
T
L
N
Site 66
S463
Y
D
E
R
S
D
S
S
D
S
R
T
L
N
T
Site 67
S465
E
R
S
D
S
S
D
S
R
T
L
N
T
S
S
Site 68
T467
S
D
S
S
D
S
R
T
L
N
T
S
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation