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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PHF15
Full Name:
Protein Jade-2
Alias:
PHD finger protein 15
Type:
Mass (Da):
87466
Number AA:
790
UniProt ID:
Q9NQC1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
E
E
K
R
R
K
Y
S
I
S
S
D
N
S
Site 2
S9
E
E
K
R
R
K
Y
S
I
S
S
D
N
S
D
Site 3
S11
K
R
R
K
Y
S
I
S
S
D
N
S
D
T
T
Site 4
S12
R
R
K
Y
S
I
S
S
D
N
S
D
T
T
D
Site 5
S15
Y
S
I
S
S
D
N
S
D
T
T
D
S
H
A
Site 6
T18
S
S
D
N
S
D
T
T
D
S
H
A
T
S
T
Site 7
S20
D
N
S
D
T
T
D
S
H
A
T
S
T
S
A
Site 8
S24
T
T
D
S
H
A
T
S
T
S
A
S
R
C
S
Site 9
S26
D
S
H
A
T
S
T
S
A
S
R
C
S
K
L
Site 10
S28
H
A
T
S
T
S
A
S
R
C
S
K
L
P
S
Site 11
S31
S
T
S
A
S
R
C
S
K
L
P
S
S
T
K
Site 12
S35
S
R
C
S
K
L
P
S
S
T
K
S
G
W
P
Site 13
S36
R
C
S
K
L
P
S
S
T
K
S
G
W
P
R
Site 14
S39
K
L
P
S
S
T
K
S
G
W
P
R
Q
N
E
Site 15
S50
R
Q
N
E
K
K
P
S
E
V
F
R
T
D
L
Site 16
T55
K
P
S
E
V
F
R
T
D
L
I
T
A
M
K
Site 17
S66
T
A
M
K
I
P
D
S
Y
Q
L
S
P
D
D
Site 18
Y67
A
M
K
I
P
D
S
Y
Q
L
S
P
D
D
Y
Site 19
S70
I
P
D
S
Y
Q
L
S
P
D
D
Y
Y
I
L
Site 20
Y74
Y
Q
L
S
P
D
D
Y
Y
I
L
A
D
P
W
Site 21
Y75
Q
L
S
P
D
D
Y
Y
I
L
A
D
P
W
R
Site 22
S117
E
G
P
P
A
Q
A
S
P
S
S
T
M
L
G
Site 23
S119
P
P
A
Q
A
S
P
S
S
T
M
L
G
E
G
Site 24
S120
P
A
Q
A
S
P
S
S
T
M
L
G
E
G
S
Site 25
T121
A
Q
A
S
P
S
S
T
M
L
G
E
G
S
Q
Site 26
S127
S
T
M
L
G
E
G
S
Q
P
D
W
P
G
G
Site 27
Y145
D
L
D
E
I
D
A
Y
W
L
E
L
I
N
S
Site 28
S152
Y
W
L
E
L
I
N
S
E
L
K
E
M
E
R
Site 29
T166
R
P
E
L
D
E
L
T
L
E
R
V
L
E
E
Site 30
T176
R
V
L
E
E
L
E
T
L
C
H
Q
N
M
A
Site 31
Y196
Q
E
G
L
G
I
E
Y
D
E
D
V
V
C
D
Site 32
S207
V
V
C
D
V
C
R
S
P
E
G
E
D
G
N
Site 33
T267
R
G
G
A
L
K
P
T
R
S
G
T
K
W
V
Site 34
S269
G
A
L
K
P
T
R
S
G
T
K
W
V
H
V
Site 35
T271
L
K
P
T
R
S
G
T
K
W
V
H
V
S
C
Site 36
S305
K
I
S
H
I
P
A
S
R
W
A
L
S
C
S
Site 37
S310
P
A
S
R
W
A
L
S
C
S
L
C
K
E
C
Site 38
S312
S
R
W
A
L
S
C
S
L
C
K
E
C
T
G
Site 39
S359
N
D
E
V
K
F
K
S
F
C
Q
E
H
S
D
Site 40
S365
K
S
F
C
Q
E
H
S
D
G
G
P
R
N
E
Site 41
T374
G
G
P
R
N
E
P
T
S
E
P
T
E
P
S
Site 42
S375
G
P
R
N
E
P
T
S
E
P
T
E
P
S
Q
Site 43
S381
T
S
E
P
T
E
P
S
Q
A
G
E
D
L
E
Site 44
T391
G
E
D
L
E
K
V
T
L
R
K
Q
R
L
Q
Site 45
Y405
Q
Q
L
E
E
D
F
Y
E
L
V
E
P
A
E
Site 46
Y428
E
A
L
V
D
F
I
Y
Q
Y
W
K
L
K
R
Site 47
T445
N
A
N
Q
P
L
L
T
P
K
T
D
E
V
D
Site 48
T448
Q
P
L
L
T
P
K
T
D
E
V
D
N
L
A
Site 49
Y463
Q
Q
E
Q
D
V
L
Y
R
R
L
K
L
F
T
Site 50
T470
Y
R
R
L
K
L
F
T
H
L
R
Q
D
L
E
Site 51
Y484
E
R
V
R
N
L
C
Y
M
V
T
R
R
E
R
Site 52
T492
M
V
T
R
R
E
R
T
K
H
A
I
C
K
L
Site 53
S520
Q
D
L
C
R
G
L
S
T
S
F
P
I
D
G
Site 54
T575
E
L
L
Q
D
E
E
T
L
L
S
F
M
R
D
Site 55
S578
Q
D
E
E
T
L
L
S
F
M
R
D
P
S
L
Site 56
S584
L
S
F
M
R
D
P
S
L
R
P
G
D
P
A
Site 57
T598
A
R
K
A
R
G
R
T
R
L
P
A
K
K
K
Site 58
S617
P
P
Q
D
G
P
G
S
R
T
T
P
D
K
A
Site 59
T620
D
G
P
G
S
R
T
T
P
D
K
A
P
K
K
Site 60
S635
T
W
G
Q
D
A
G
S
G
K
G
G
Q
G
P
Site 61
T644
K
G
G
Q
G
P
P
T
R
K
P
P
R
R
T
Site 62
T651
T
R
K
P
P
R
R
T
S
S
H
L
P
S
S
Site 63
S652
R
K
P
P
R
R
T
S
S
H
L
P
S
S
P
Site 64
S653
K
P
P
R
R
T
S
S
H
L
P
S
S
P
A
Site 65
S657
R
T
S
S
H
L
P
S
S
P
A
A
G
D
C
Site 66
S658
T
S
S
H
L
P
S
S
P
A
A
G
D
C
P
Site 67
T669
G
D
C
P
I
L
A
T
P
E
S
P
P
P
L
Site 68
S672
P
I
L
A
T
P
E
S
P
P
P
L
A
P
E
Site 69
T680
P
P
P
L
A
P
E
T
P
D
E
A
A
S
V
Site 70
S701
Q
V
P
G
P
A
A
S
P
K
P
L
G
R
L
Site 71
S714
R
L
R
P
P
R
E
S
K
V
T
R
R
L
P
Site 72
T717
P
P
R
E
S
K
V
T
R
R
L
P
G
A
R
Site 73
S733
D
A
G
M
G
P
P
S
A
V
A
E
R
P
K
Site 74
T747
K
V
S
L
H
F
D
T
E
T
D
G
Y
F
S
Site 75
T749
S
L
H
F
D
T
E
T
D
G
Y
F
S
D
G
Site 76
Y752
F
D
T
E
T
D
G
Y
F
S
D
G
E
M
S
Site 77
S754
T
E
T
D
G
Y
F
S
D
G
E
M
S
D
S
Site 78
S759
Y
F
S
D
G
E
M
S
D
S
D
V
E
A
E
Site 79
S761
S
D
G
E
M
S
D
S
D
V
E
A
E
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation