KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TRIM36
Full Name:
E3 ubiquitin-protein ligase TRIM36
Alias:
RING finger protein 98;Tripartite motif-containing protein 36;Zinc-binding protein Rbcc728
Type:
Mass (Da):
83012
Number AA:
728
UniProt ID:
Q9NQ86
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
E
S
G
E
M
S
E
F
G
Y
I
M
E
Site 2
S67
L
L
L
T
L
D
D
S
F
N
D
V
G
S
D
Site 3
S73
D
S
F
N
D
V
G
S
D
N
S
N
Q
S
S
Site 4
S76
N
D
V
G
S
D
N
S
N
Q
S
S
P
R
L
Site 5
S79
G
S
D
N
S
N
Q
S
S
P
R
L
R
L
P
Site 6
S80
S
D
N
S
N
Q
S
S
P
R
L
R
L
P
S
Site 7
S87
S
P
R
L
R
L
P
S
P
S
M
D
K
I
D
Site 8
S89
R
L
R
L
P
S
P
S
M
D
K
I
D
R
I
Site 9
S105
R
P
G
W
K
R
N
S
L
T
P
R
T
T
V
Site 10
T107
G
W
K
R
N
S
L
T
P
R
T
T
V
F
P
Site 11
T110
R
N
S
L
T
P
R
T
T
V
F
P
C
P
G
Site 12
T111
N
S
L
T
P
R
T
T
V
F
P
C
P
G
C
Site 13
T137
N
G
L
F
R
N
F
T
L
E
T
I
V
E
R
Site 14
S170
P
P
Q
E
S
T
K
S
C
M
D
C
S
A
S
Site 15
S175
T
K
S
C
M
D
C
S
A
S
Y
C
N
E
C
Site 16
S177
S
C
M
D
C
S
A
S
Y
C
N
E
C
F
K
Site 17
Y178
C
M
D
C
S
A
S
Y
C
N
E
C
F
K
I
Site 18
Y198
T
I
K
A
Q
H
E
Y
V
G
P
T
T
N
F
Site 19
Y223
E
T
E
R
I
N
M
Y
C
E
L
C
R
R
P
Site 20
T247
N
H
A
N
H
R
V
T
T
M
S
S
A
Y
K
Site 21
T248
H
A
N
H
R
V
T
T
M
S
S
A
Y
K
T
Site 22
S250
N
H
R
V
T
T
M
S
S
A
Y
K
T
L
K
Site 23
Y253
V
T
T
M
S
S
A
Y
K
T
L
K
E
K
L
Site 24
T255
T
M
S
S
A
Y
K
T
L
K
E
K
L
S
K
Site 25
S261
K
T
L
K
E
K
L
S
K
D
I
D
Y
L
I
Site 26
Y266
K
L
S
K
D
I
D
Y
L
I
G
K
E
S
Q
Site 27
S272
D
Y
L
I
G
K
E
S
Q
V
K
S
Q
I
S
Site 28
S276
G
K
E
S
Q
V
K
S
Q
I
S
E
L
N
L
Site 29
S279
S
Q
V
K
S
Q
I
S
E
L
N
L
L
M
K
Site 30
T301
R
A
K
E
E
A
I
T
H
F
E
K
L
F
E
Site 31
S315
E
V
L
E
E
R
K
S
S
V
L
K
A
I
D
Site 32
S316
V
L
E
E
R
K
S
S
V
L
K
A
I
D
S
Site 33
S323
S
V
L
K
A
I
D
S
S
K
K
L
R
L
D
Site 34
S362
V
L
K
E
T
D
Q
S
C
F
V
Q
T
A
K
Site 35
T379
H
L
R
I
Q
K
A
T
E
S
L
K
S
F
R
Site 36
S381
R
I
Q
K
A
T
E
S
L
K
S
F
R
P
A
Site 37
S384
K
A
T
E
S
L
K
S
F
R
P
A
A
Q
T
Site 38
T391
S
F
R
P
A
A
Q
T
S
F
E
D
Y
V
V
Site 39
S392
F
R
P
A
A
Q
T
S
F
E
D
Y
V
V
N
Site 40
Y396
A
Q
T
S
F
E
D
Y
V
V
N
T
S
K
Q
Site 41
Y448
E
K
D
K
A
D
S
Y
V
L
E
Y
R
K
I
Site 42
T483
Q
D
L
E
N
S
S
T
Y
A
F
R
V
R
A
Site 43
Y491
Y
A
F
R
V
R
A
Y
K
G
S
I
C
S
P
Site 44
S494
R
V
R
A
Y
K
G
S
I
C
S
P
C
S
R
Site 45
S497
A
Y
K
G
S
I
C
S
P
C
S
R
E
L
I
Site 46
Y523
L
F
D
E
K
C
G
Y
N
N
E
H
L
L
L
Site 47
S539
L
K
R
D
R
V
E
S
R
A
G
F
N
L
L
Site 48
Y556
A
E
R
I
Q
V
G
Y
Y
T
S
L
D
Y
I
Site 49
Y583
W
A
F
R
V
E
P
Y
S
Y
L
V
K
V
G
Site 50
Y585
F
R
V
E
P
Y
S
Y
L
V
K
V
G
V
A
Site 51
S603
K
L
Q
E
W
L
R
S
P
R
D
A
V
S
P
Site 52
S609
R
S
P
R
D
A
V
S
P
R
Y
E
Q
D
S
Site 53
Y612
R
D
A
V
S
P
R
Y
E
Q
D
S
G
H
D
Site 54
S616
S
P
R
Y
E
Q
D
S
G
H
D
S
G
S
E
Site 55
S620
E
Q
D
S
G
H
D
S
G
S
E
D
A
C
F
Site 56
S622
D
S
G
H
D
S
G
S
E
D
A
C
F
D
S
Site 57
S629
S
E
D
A
C
F
D
S
S
Q
P
F
T
L
V
Site 58
S630
E
D
A
C
F
D
S
S
Q
P
F
T
L
V
T
Site 59
S648
Q
K
F
F
I
P
K
S
P
T
S
S
N
E
P
Site 60
S651
F
I
P
K
S
P
T
S
S
N
E
P
E
N
R
Site 61
S652
I
P
K
S
P
T
S
S
N
E
P
E
N
R
V
Site 62
Y680
D
K
G
K
V
N
F
Y
D
M
D
Q
M
K
C
Site 63
Y689
M
D
Q
M
K
C
L
Y
E
R
Q
V
D
C
S
Site 64
T718
I
Q
L
E
E
P
I
T
A
K
Y
L
E
Y
Q
Site 65
Y721
E
E
P
I
T
A
K
Y
L
E
Y
Q
E
D
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation