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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPR108
Full Name:
Protein GPR108
Alias:
Lung seven transmembrane receptor 2
Type:
Mass (Da):
60633
Number AA:
543
UniProt ID:
Q9NPR9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
R
R
G
L
G
R
G
S
P
A
E
W
G
Q
R
Site 2
S51
R
A
D
I
Q
L
N
S
F
G
F
Y
T
N
G
Site 3
Y55
Q
L
N
S
F
G
F
Y
T
N
G
S
L
E
V
Site 4
S90
F
S
L
S
R
V
R
S
G
R
V
R
S
Y
S
Site 5
S95
V
R
S
G
R
V
R
S
Y
S
T
R
D
F
Q
Site 6
Y96
R
S
G
R
V
R
S
Y
S
T
R
D
F
Q
D
Site 7
S97
S
G
R
V
R
S
Y
S
T
R
D
F
Q
D
C
Site 8
Y131
L
Q
V
Q
V
R
K
Y
G
E
Q
K
T
L
F
Site 9
T136
R
K
Y
G
E
Q
K
T
L
F
I
F
P
G
L
Site 10
S149
G
L
L
P
E
A
P
S
K
P
G
L
P
K
P
Site 11
T159
G
L
P
K
P
Q
A
T
V
P
R
K
V
D
G
Site 12
S170
K
V
D
G
G
G
T
S
A
A
S
K
P
K
S
Site 13
S173
G
G
G
T
S
A
A
S
K
P
K
S
T
P
A
Site 14
S177
S
A
A
S
K
P
K
S
T
P
A
V
I
Q
G
Site 15
T178
A
A
S
K
P
K
S
T
P
A
V
I
Q
G
P
Site 16
S197
K
D
L
V
L
G
L
S
H
L
N
N
S
Y
N
Site 17
Y203
L
S
H
L
N
N
S
Y
N
F
S
F
H
V
V
Site 18
S213
S
F
H
V
V
I
G
S
Q
A
E
E
G
Q
Y
Site 19
Y220
S
Q
A
E
E
G
Q
Y
S
L
N
F
H
N
C
Site 20
T241
K
E
H
P
F
D
I
T
V
M
I
R
E
K
N
Site 21
S254
K
N
P
D
G
F
L
S
A
A
E
M
P
L
F
Site 22
Y315
L
F
H
S
I
N
Y
Y
F
I
N
S
Q
G
H
Site 23
Y358
S
G
W
A
F
I
K
Y
V
L
S
D
K
E
K
Site 24
S361
A
F
I
K
Y
V
L
S
D
K
E
K
K
V
F
Site 25
S393
E
S
R
E
E
G
A
S
D
Y
V
L
W
K
E
Site 26
Y395
R
E
E
G
A
S
D
Y
V
L
W
K
E
I
L
Site 27
Y477
P
F
Q
W
Q
W
L
Y
Q
L
L
V
E
G
S
Site 28
T522
V
Q
M
E
Q
V
M
T
D
S
G
F
R
E
G
Site 29
S524
M
E
Q
V
M
T
D
S
G
F
R
E
G
L
S
Site 30
S531
S
G
F
R
E
G
L
S
K
V
N
K
T
A
S
Site 31
S538
S
K
V
N
K
T
A
S
G
R
E
L
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation