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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IL1RAP
Full Name:
Interleukin-1 receptor accessory protein
Alias:
C3orf13; IL-1 receptor accessory; IL1AP; IL1R3; IL-1RAcP; Interleukin 1 receptor accessory protein; Interleukin-1 receptor accessory
Type:
Receptor, misc.
Mass (Da):
65418
Number AA:
570
UniProt ID:
Q9NPH3
International Prot ID:
IPI00031789
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0004908
PhosphoSite+
KinaseNET
Biological Process:
GO:0006954
GO:0045087
GO:0006461
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
Y
F
Y
G
I
L
Q
S
D
A
S
E
R
C
D
Site 2
Y166
T
C
P
N
V
D
G
Y
F
P
S
S
V
K
P
Site 3
Y178
V
K
P
T
I
T
W
Y
M
G
C
Y
K
I
Q
Site 4
Y182
I
T
W
Y
M
G
C
Y
K
I
Q
N
F
N
N
Site 5
T293
G
K
K
P
D
D
I
T
I
D
V
T
I
N
E
Site 6
S303
V
T
I
N
E
S
I
S
H
S
R
T
E
D
E
Site 7
T395
F
Y
R
A
H
F
G
T
D
E
T
I
L
D
G
Site 8
T398
A
H
F
G
T
D
E
T
I
L
D
G
K
E
Y
Site 9
Y405
T
I
L
D
G
K
E
Y
D
I
Y
V
S
Y
A
Site 10
Y408
D
G
K
E
Y
D
I
Y
V
S
Y
A
R
N
A
Site 11
Y411
E
Y
D
I
Y
V
S
Y
A
R
N
A
E
E
E
Site 12
T454
G
G
I
V
T
D
E
T
L
S
F
I
Q
K
S
Site 13
S456
I
V
T
D
E
T
L
S
F
I
Q
K
S
R
R
Site 14
T509
Q
Y
K
A
V
K
E
T
K
V
K
E
L
K
R
Site 15
T519
K
E
L
K
R
A
K
T
V
L
T
V
I
K
W
Site 16
T522
K
R
A
K
T
V
L
T
V
I
K
W
K
G
E
Site 17
Y533
W
K
G
E
K
S
K
Y
P
Q
G
R
F
W
K
Site 18
S551
V
A
M
P
V
K
K
S
P
R
R
S
S
S
D
Site 19
S555
V
K
K
S
P
R
R
S
S
S
D
E
Q
G
L
Site 20
S556
K
K
S
P
R
R
S
S
S
D
E
Q
G
L
S
Site 21
S557
K
S
P
R
R
S
S
S
D
E
Q
G
L
S
Y
Site 22
S563
S
S
D
E
Q
G
L
S
Y
S
S
L
K
N
V
Site 23
Y564
S
D
E
Q
G
L
S
Y
S
S
L
K
N
V
_
Site 24
S566
E
Q
G
L
S
Y
S
S
L
K
N
V
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation