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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PCDH12
Full Name:
Protocadherin-12
Alias:
PCD12; protocadherin 12; protocadherin-12; VE-cad-2; VE-cadherin 2; VE-cadherin-2
Type:
Mass (Da):
128990
Number AA:
UniProt ID:
Q9NPG4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0008038
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y34
V
T
T
L
T
V
K
Y
Q
V
S
E
E
V
P
Site 2
T742
L
F
M
S
I
C
R
T
E
K
K
D
N
R
A
Site 3
Y750
E
K
K
D
N
R
A
Y
N
C
R
E
A
E
S
Site 4
T758
N
C
R
E
A
E
S
T
Y
R
Q
Q
P
K
R
Site 5
T821
A
P
F
H
L
T
P
T
L
Y
R
T
L
R
N
Site 6
Y823
F
H
L
T
P
T
L
Y
R
T
L
R
N
Q
G
Site 7
T825
L
T
P
T
L
Y
R
T
L
R
N
Q
G
N
Q
Site 8
T845
S
R
E
V
L
Q
D
T
V
N
L
L
F
N
H
Site 9
S859
H
P
R
Q
R
N
A
S
R
E
N
L
N
L
P
Site 10
T872
L
P
E
P
Q
P
A
T
G
Q
P
R
S
R
P
Site 11
S877
P
A
T
G
Q
P
R
S
R
P
L
K
V
A
G
Site 12
S885
R
P
L
K
V
A
G
S
P
T
G
R
L
A
G
Site 13
S896
R
L
A
G
D
Q
G
S
E
E
A
P
Q
R
P
Site 14
S906
A
P
Q
R
P
P
A
S
S
A
T
L
R
R
Q
Site 15
S907
P
Q
R
P
P
A
S
S
A
T
L
R
R
Q
R
Site 16
T909
R
P
P
A
S
S
A
T
L
R
R
Q
R
H
L
Site 17
S921
R
H
L
N
G
K
V
S
P
E
K
E
S
G
P
Site 18
S926
K
V
S
P
E
K
E
S
G
P
R
Q
I
L
R
Site 19
T953
R
N
P
V
E
E
L
T
V
D
S
P
P
V
Q
Site 20
S956
V
E
E
L
T
V
D
S
P
P
V
Q
Q
I
S
Site 21
S967
Q
Q
I
S
Q
L
L
S
L
L
H
Q
G
Q
F
Site 22
Y985
P
N
H
R
G
N
K
Y
L
A
K
P
G
G
S
Site 23
S994
A
K
P
G
G
S
R
S
A
I
P
D
T
D
G
Site 24
T999
S
R
S
A
I
P
D
T
D
G
P
S
A
R
A
Site 25
S1003
I
P
D
T
D
G
P
S
A
R
A
G
G
Q
T
Site 26
T1010
S
A
R
A
G
G
Q
T
D
P
E
Q
E
E
G
Site 27
S1026
L
D
P
E
E
D
L
S
V
K
Q
L
L
E
E
Site 28
S1036
Q
L
L
E
E
E
L
S
S
L
L
D
P
S
T
Site 29
S1037
L
L
E
E
E
L
S
S
L
L
D
P
S
T
G
Site 30
S1062
P
A
W
M
A
R
L
S
L
P
L
T
T
N
Y
Site 31
T1066
A
R
L
S
L
P
L
T
T
N
Y
R
D
N
V
Site 32
Y1069
S
L
P
L
T
T
N
Y
R
D
N
V
I
S
P
Site 33
S1075
N
Y
R
D
N
V
I
S
P
D
A
A
A
T
E
Site 34
T1081
I
S
P
D
A
A
A
T
E
E
P
R
T
F
Q
Site 35
T1086
A
A
T
E
E
P
R
T
F
Q
T
F
G
K
A
Site 36
S1099
K
A
E
A
P
E
L
S
P
T
G
T
R
L
A
Site 37
T1101
E
A
P
E
L
S
P
T
G
T
R
L
A
S
T
Site 38
T1103
P
E
L
S
P
T
G
T
R
L
A
S
T
F
V
Site 39
S1107
P
T
G
T
R
L
A
S
T
F
V
S
E
M
S
Site 40
T1108
T
G
T
R
L
A
S
T
F
V
S
E
M
S
S
Site 41
S1125
E
M
L
L
E
Q
R
S
S
M
P
V
E
A
A
Site 42
S1126
M
L
L
E
Q
R
S
S
M
P
V
E
A
A
S
Site 43
S1140
S
E
A
L
R
R
L
S
V
C
G
R
T
L
S
Site 44
T1168
Q
G
D
P
G
G
K
T
G
T
E
G
K
S
R
Site 45
T1170
D
P
G
G
K
T
G
T
E
G
K
S
R
G
S
Site 46
S1174
K
T
G
T
E
G
K
S
R
G
S
S
S
S
S
Site 47
S1177
T
E
G
K
S
R
G
S
S
S
S
S
R
C
L
Site 48
S1178
E
G
K
S
R
G
S
S
S
S
S
R
C
L
_
Site 49
S1179
G
K
S
R
G
S
S
S
S
S
R
C
L
_
_
Site 50
S1180
K
S
R
G
S
S
S
S
S
R
C
L
_
_
_
Site 51
S1181
S
R
G
S
S
S
S
S
R
C
L
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation