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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADAP2
Full Name:
Arf-GAP with dual PH domain-containing protein 2
Alias:
Centaurin-alpha-2
Type:
Mass (Da):
44349
Number AA:
381
UniProt ID:
Q9NPF8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
E
L
L
R
A
P
D
T
G
N
A
H
C
A
D
Site 2
S59
H
R
N
F
P
D
I
S
R
V
K
S
V
R
L
Site 3
S63
P
D
I
S
R
V
K
S
V
R
L
D
F
W
D
Site 4
Y97
E
A
R
V
P
A
F
Y
Y
I
P
Q
A
N
D
Site 5
Y117
E
Q
W
I
R
A
K
Y
E
R
R
E
F
M
A
Site 6
T128
E
F
M
A
D
G
E
T
I
S
L
P
G
N
R
Site 7
S130
M
A
D
G
E
T
I
S
L
P
G
N
R
E
G
Site 8
S147
W
K
R
G
R
D
N
S
Q
F
L
R
R
K
F
Site 9
Y165
A
R
E
G
L
L
K
Y
F
T
K
E
Q
G
K
Site 10
T167
E
G
L
L
K
Y
F
T
K
E
Q
G
K
S
P
Site 11
S173
F
T
K
E
Q
G
K
S
P
K
A
V
I
S
I
Site 12
T186
S
I
K
D
L
N
A
T
F
Q
T
E
K
I
G
Site 13
T201
H
P
H
G
L
Q
I
T
Y
R
R
D
G
H
T
Site 14
Y202
P
H
G
L
Q
I
T
Y
R
R
D
G
H
T
R
Site 15
T208
T
Y
R
R
D
G
H
T
R
N
L
F
V
Y
H
Site 16
Y214
H
T
R
N
L
F
V
Y
H
E
S
G
K
E
I
Site 17
Y235
L
R
A
A
R
L
Q
Y
L
K
M
A
F
P
E
Site 18
T253
S
E
L
V
P
F
L
T
R
N
Y
L
K
Q
G
Site 19
Y256
V
P
F
L
T
R
N
Y
L
K
Q
G
F
M
E
Site 20
Y289
C
H
E
R
R
L
L
Y
Y
K
N
P
L
D
A
Site 21
Y290
H
E
R
R
L
L
Y
Y
K
N
P
L
D
A
F
Site 22
Y311
L
G
N
K
E
Q
G
Y
E
A
Y
E
D
L
P
Site 23
T342
P
E
R
R
F
V
L
T
C
P
S
E
K
E
Q
Site 24
S345
R
F
V
L
T
C
P
S
E
K
E
Q
Q
E
W
Site 25
S355
E
Q
Q
E
W
L
E
S
L
R
G
V
L
S
S
Site 26
S361
E
S
L
R
G
V
L
S
S
P
L
T
P
L
N
Site 27
S362
S
L
R
G
V
L
S
S
P
L
T
P
L
N
R
Site 28
T371
L
T
P
L
N
R
L
T
A
S
T
E
S
G
R
Site 29
S373
P
L
N
R
L
T
A
S
T
E
S
G
R
S
S
Site 30
T374
L
N
R
L
T
A
S
T
E
S
G
R
S
S
R
Site 31
S376
R
L
T
A
S
T
E
S
G
R
S
S
R
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation