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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCNB1IP1
Full Name:
E3 ubiquitin-protein ligase CCNB1IP1
Alias:
C14orf18; CIP1; Cyclin B1-interacting 1; E3 ubiquitin-protein ligase HEI10; EC 6.3.2.-; Enhancer of invasion 10; Enhancer of invasion 10 - fused to HMGA2; HEI10; Human enhancer of invasion 10
Type:
Ubiquitin conjugating system, Cell cycle regulation, Ligase
Mass (Da):
31544
Number AA:
277
UniProt ID:
Q9NPC3
International Prot ID:
IPI00009603
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0016874
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S38
I
F
C
D
Q
H
G
S
G
E
F
S
R
S
P
Site 2
S42
Q
H
G
S
G
E
F
S
R
S
P
A
I
C
P
Site 3
S44
G
S
G
E
F
S
R
S
P
A
I
C
P
A
C
Site 4
T64
G
K
L
D
I
V
R
T
E
L
S
P
S
E
E
Site 5
S67
D
I
V
R
T
E
L
S
P
S
E
E
Y
K
A
Site 6
S69
V
R
T
E
L
S
P
S
E
E
Y
K
A
M
V
Site 7
Y98
R
A
L
A
F
W
T
Y
Q
V
H
Q
E
R
L
Site 8
Y106
Q
V
H
Q
E
R
L
Y
Q
E
Y
N
F
S
K
Site 9
Y109
Q
E
R
L
Y
Q
E
Y
N
F
S
K
A
E
G
Site 10
Y125
L
K
Q
M
E
K
I
Y
T
Q
Q
I
Q
S
K
Site 11
T126
K
Q
M
E
K
I
Y
T
Q
Q
I
Q
S
K
D
Site 12
S138
S
K
D
V
E
L
T
S
M
K
G
E
V
T
S
Site 13
S145
S
M
K
G
E
V
T
S
M
K
K
V
L
E
E
Site 14
S158
E
E
Y
K
K
K
F
S
D
I
S
E
K
L
M
Site 15
S161
K
K
K
F
S
D
I
S
E
K
L
M
E
R
N
Site 16
Y171
L
M
E
R
N
R
Q
Y
Q
K
L
Q
G
L
Y
Site 17
Y178
Y
Q
K
L
Q
G
L
Y
D
S
L
R
L
R
N
Site 18
S180
K
L
Q
G
L
Y
D
S
L
R
L
R
N
I
T
Site 19
T187
S
L
R
L
R
N
I
T
I
A
N
H
E
G
T
Site 20
T194
T
I
A
N
H
E
G
T
L
E
P
S
M
I
A
Site 21
S198
H
E
G
T
L
E
P
S
M
I
A
Q
S
G
V
Site 22
S214
G
F
P
L
G
N
N
S
K
F
P
L
D
N
T
Site 23
T221
S
K
F
P
L
D
N
T
P
V
R
N
R
G
D
Site 24
S242
F
R
P
F
F
A
G
S
P
T
A
P
E
P
S
Site 25
T244
P
F
F
A
G
S
P
T
A
P
E
P
S
N
S
Site 26
S249
S
P
T
A
P
E
P
S
N
S
F
F
S
F
V
Site 27
S251
T
A
P
E
P
S
N
S
F
F
S
F
V
S
P
Site 28
S254
E
P
S
N
S
F
F
S
F
V
S
P
S
R
E
Site 29
S257
N
S
F
F
S
F
V
S
P
S
R
E
L
E
Q
Site 30
S268
E
L
E
Q
Q
Q
V
S
S
R
A
F
K
V
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation