PhosphoNET

           
Protein Info 
   
Short Name:  PARD6A
Full Name:  Partitioning defective 6 homolog alpha
Alias:  PAR-6; PAR-6 alpha; Par-6 partitioning defective 6 alpha; PAR6A; PAR-6A; PAR6alpha; PAR6C; Tax interaction protein 40; TAX40; TIP-40
Type: 
Mass (Da):  37388
Number AA:  346
UniProt ID:  Q9NPB6
International Prot ID:  IPI00027217
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0001726  GO:0005923 Uniprot OncoNet
Molecular Function:  GO:0030742  GO:0017048  GO:0008134 PhosphoSite+ KinaseNET
Biological Process:  GO:0007049  GO:0051301  GO:0045217 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T7_MARPQRTPARSPDS
Site 2S11PQRTPARSPDSIVEV
Site 3S14TPARSPDSIVEVKSK
Site 4S35RFALPRASVSGFQEF
Site 5T72HGDLLPLTNDDSLHR
Site 6S76LPLTNDDSLHRALAS
Site 7S83SLHRALASGPPPLRL
Site 8S100QKRAEADSSGLAFAS
Site 9S101KRAEADSSGLAFASN
Site 10S107SSGLAFASNSLQRRK
Site 11S109GLAFASNSLQRRKKG
Site 12T127RPVAPLRTRPPLLIS
Site 13S143PQDFRQVSSVIDVDL
Site 14T154DVDLLPETHRRVRLH
Site 15S165VRLHKHGSDRPLGFY
Site 16Y172SDRPLGFYIRDGMSV
Site 17S178FYIRDGMSVRVAPQG
Site 18T227GIEVAGKTLDQVTDM
Site 19T245NSHNLIVTVKPANQR
Site 20S260NNVVRGASGRLTGPP
Site 21T264RGASGRLTGPPSAGP
Site 22S268GRLTGPPSAGPGPAE
Site 23S278PGPAEPDSDDDSSDL
Site 24S282EPDSDDDSSDLVIEN
Site 25S283PDSDDDSSDLVIENR
Site 26S294IENRQPPSSNGLSQG
Site 27S295ENRQPPSSNGLSQGP
Site 28S299PPSSNGLSQGPPCWD
Site 29T316PGCRHPGTRSSLPSL
Site 30S318CRHPGTRSSLPSLDD
Site 31S319RHPGTRSSLPSLDDQ
Site 32S322GTRSSLPSLDDQEQA
Site 33S331DDQEQASSGWGSRIR
Site 34S335QASSGWGSRIRGDGS
Site 35S342SRIRGDGSGFSL___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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