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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SARS2
Full Name:
Seryl-tRNA synthetase, mitochondrial
Alias:
FLJ20450; MtSerRS; SARS; SARSM; Serine tRNA ligase 2, mitochondrial; Serine-tRNA ligase; Serine--tRNA ligase; SerRSmt; SERS; Seryl-tRNA synthetase 2, mitochondrial; Seryl-tRNA synthetase, mitochondrial; Seryl-tRNA(Ser,Sec) synthetase; Seryl-tRNA(Ser/Sec) synthetase; SYS; SYSM
Type:
Ligase; EC 6.1.1.11
Mass (Da):
58283
Number AA:
518
UniProt ID:
Q9NP81
International Prot ID:
IPI00328361
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005739
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003824
GO:0004812
PhosphoSite+
KinaseNET
Biological Process:
GO:0006082
GO:0006139
GO:0006399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
R
R
L
W
P
L
L
T
R
R
G
F
R
P
R
Site 2
S26
R
P
R
G
G
C
I
S
N
D
S
P
R
R
S
Site 3
S29
G
G
C
I
S
N
D
S
P
R
R
S
F
T
T
Site 4
S33
S
N
D
S
P
R
R
S
F
T
T
E
K
R
N
Site 5
T35
D
S
P
R
R
S
F
T
T
E
K
R
N
R
N
Site 6
T36
S
P
R
R
S
F
T
T
E
K
R
N
R
N
L
Site 7
Y45
K
R
N
R
N
L
L
Y
E
Y
A
R
E
G
Y
Site 8
Y47
N
R
N
L
L
Y
E
Y
A
R
E
G
Y
S
A
Site 9
Y52
Y
E
Y
A
R
E
G
Y
S
A
L
P
Q
L
D
Site 10
S91
A
D
L
P
A
I
I
S
T
W
Q
E
L
R
Q
Site 11
S105
Q
L
Q
E
Q
I
R
S
L
E
E
E
K
A
A
Site 12
S126
A
L
L
A
N
Q
D
S
G
E
V
Q
Q
D
P
Site 13
Y135
E
V
Q
Q
D
P
K
Y
Q
G
L
R
A
R
G
Site 14
Y153
R
K
E
L
V
H
L
Y
P
R
E
A
Q
L
E
Site 15
Y164
A
Q
L
E
E
Q
F
Y
L
Q
A
L
K
L
P
Site 16
S184
D
V
P
V
G
D
E
S
Q
A
R
V
L
H
M
Site 17
S199
V
G
D
K
P
V
F
S
F
Q
P
R
G
H
L
Site 18
S221
I
I
R
Q
K
R
L
S
H
V
S
G
H
R
S
Site 19
S224
Q
K
R
L
S
H
V
S
G
H
R
S
Y
Y
L
Site 20
S228
S
H
V
S
G
H
R
S
Y
Y
L
R
G
A
G
Site 21
Y229
H
V
S
G
H
R
S
Y
Y
L
R
G
A
G
A
Site 22
Y230
V
S
G
H
R
S
Y
Y
L
R
G
A
G
A
L
Site 23
T246
Q
H
G
L
V
N
F
T
F
N
K
L
L
R
R
Site 24
T256
K
L
L
R
R
G
F
T
P
M
T
V
P
D
L
Site 25
T259
R
R
G
F
T
P
M
T
V
P
D
L
L
R
G
Site 26
T275
V
F
E
G
C
G
M
T
P
N
A
N
P
S
Q
Site 27
T312
A
G
Y
F
M
D
H
T
V
A
F
R
D
L
P
Site 28
Y329
M
V
C
S
S
T
C
Y
R
A
E
T
N
T
G
Site 29
T333
S
T
C
Y
R
A
E
T
N
T
G
Q
E
P
R
Site 30
Y343
G
Q
E
P
R
G
L
Y
R
V
H
H
F
T
K
Site 31
S364
T
G
P
G
L
E
Q
S
S
Q
L
L
E
E
F
Site 32
S365
G
P
G
L
E
Q
S
S
Q
L
L
E
E
F
L
Site 33
Y401
Q
E
L
G
L
P
A
Y
R
K
F
D
I
E
A
Site 34
T420
R
G
R
F
G
E
V
T
S
A
S
N
C
T
D
Site 35
S421
G
R
F
G
E
V
T
S
A
S
N
C
T
D
F
Site 36
T439
R
L
H
I
M
F
Q
T
E
A
G
E
L
Q
F
Site 37
S474
S
N
Q
Q
K
D
G
S
V
L
V
P
P
A
L
Site 38
T487
A
L
Q
S
Y
L
G
T
D
R
I
T
A
P
T
Site 39
T491
Y
L
G
T
D
R
I
T
A
P
T
H
V
P
L
Site 40
T494
T
D
R
I
T
A
P
T
H
V
P
L
Q
Y
I
Site 41
Y500
P
T
H
V
P
L
Q
Y
I
G
P
N
Q
P
R
Site 42
S518
L
P
G
Q
P
A
V
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation