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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HMG20A
Full Name:
High mobility group protein 20A
Alias:
High-mobility group 20A; HM20A; HMG box-containing protein 20A; HMG domain-containing protein HMGX1; HMGX1
Type:
Regulatory protein, inhibitor of HMG20B. Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4.
Mass (Da):
40144
Number AA:
347
UniProt ID:
Q9NP66
International Prot ID:
Isoform1 - IPI00018924
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005730
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003700
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0016568
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
E
N
L
M
T
S
S
T
L
P
P
L
Site 2
T9
E
N
L
M
T
S
S
T
L
P
P
L
F
A
D
Site 3
S20
L
F
A
D
E
D
G
S
K
E
S
N
D
L
A
Site 4
S39
N
H
P
E
V
P
Y
S
S
G
A
T
S
S
T
Site 5
S40
H
P
E
V
P
Y
S
S
G
A
T
S
S
T
N
Site 6
S44
P
Y
S
S
G
A
T
S
S
T
N
N
P
E
F
Site 7
S45
Y
S
S
G
A
T
S
S
T
N
N
P
E
F
V
Site 8
T46
S
S
G
A
T
S
S
T
N
N
P
E
F
V
E
Site 9
S56
P
E
F
V
E
D
L
S
Q
G
Q
L
L
Q
S
Site 10
S63
S
Q
G
Q
L
L
Q
S
E
S
S
N
A
A
E
Site 11
S65
G
Q
L
L
Q
S
E
S
S
N
A
A
E
G
N
Site 12
S66
Q
L
L
Q
S
E
S
S
N
A
A
E
G
N
E
Site 13
S82
R
H
E
D
E
Q
R
S
K
R
G
G
W
S
K
Site 14
S88
R
S
K
R
G
G
W
S
K
G
R
K
R
K
K
Site 15
S100
R
K
K
P
L
R
D
S
N
A
P
K
S
P
L
Site 16
S105
R
D
S
N
A
P
K
S
P
L
T
G
Y
V
R
Site 17
T108
N
A
P
K
S
P
L
T
G
Y
V
R
F
M
N
Site 18
Y110
P
K
S
P
L
T
G
Y
V
R
F
M
N
E
R
Site 19
S142
R
M
L
G
N
E
W
S
K
L
P
P
E
E
K
Site 20
Y152
P
P
E
E
K
Q
R
Y
L
D
E
A
D
R
D
Site 21
Y163
A
D
R
D
K
E
R
Y
M
K
E
L
E
Q
Y
Site 22
Y170
Y
M
K
E
L
E
Q
Y
Q
K
T
E
A
Y
K
Site 23
T183
Y
K
V
F
S
R
K
T
Q
D
R
Q
K
G
K
Site 24
S191
Q
D
R
Q
K
G
K
S
H
R
Q
D
A
A
R
Site 25
T201
Q
D
A
A
R
Q
A
T
H
D
H
E
K
E
T
Site 26
S214
E
T
E
V
K
E
R
S
V
F
D
I
P
I
F
Site 27
S229
T
E
E
F
L
N
H
S
K
A
R
E
A
E
L
Site 28
S242
E
L
R
Q
L
R
K
S
N
M
E
F
E
E
R
Site 29
S259
A
L
Q
K
H
V
E
S
M
R
T
A
V
E
K
Site 30
T262
K
H
V
E
S
M
R
T
A
V
E
K
L
E
V
Site 31
T279
I
Q
E
R
S
R
N
T
V
L
Q
Q
H
L
E
Site 32
T287
V
L
Q
Q
H
L
E
T
L
R
Q
V
L
T
S
Site 33
T293
E
T
L
R
Q
V
L
T
S
S
F
A
S
M
P
Site 34
S304
A
S
M
P
L
P
G
S
G
E
T
P
T
V
D
Site 35
T307
P
L
P
G
S
G
E
T
P
T
V
D
T
I
D
Site 36
T309
P
G
S
G
E
T
P
T
V
D
T
I
D
S
Y
Site 37
S315
P
T
V
D
T
I
D
S
Y
M
N
R
L
H
S
Site 38
Y316
T
V
D
T
I
D
S
Y
M
N
R
L
H
S
I
Site 39
S322
S
Y
M
N
R
L
H
S
I
I
L
A
N
P
Q
Site 40
T337
D
N
E
N
F
I
A
T
V
R
E
V
V
N
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation