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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCB6
Full Name:
ATP-binding cassette sub-family B member 6, mitochondrial
Alias:
Mitochondrial ABC transporter 3
Type:
Mass (Da):
93868
Number AA:
842
UniProt ID:
Q9NP58
International Prot ID:
IPI00742677
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005740
GO:0005741
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003824
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006873
GO:0006879
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S61
E
R
P
A
G
A
D
S
L
S
W
G
A
G
P
Site 2
S63
P
A
G
A
D
S
L
S
W
G
A
G
P
R
I
Site 3
S130
W
L
L
V
V
E
R
S
Q
A
R
Q
R
L
A
Site 4
S213
A
P
G
L
R
P
Q
S
Y
T
L
Q
V
H
E
Site 5
Y214
P
G
L
R
P
Q
S
Y
T
L
Q
V
H
E
E
Site 6
T215
G
L
R
P
Q
S
Y
T
L
Q
V
H
E
E
D
Site 7
S228
E
D
Q
D
V
E
R
S
Q
V
R
S
A
A
Q
Site 8
S232
V
E
R
S
Q
V
R
S
A
A
Q
Q
S
T
W
Site 9
S237
V
R
S
A
A
Q
Q
S
T
W
R
D
F
G
R
Site 10
T238
R
S
A
A
Q
Q
S
T
W
R
D
F
G
R
K
Site 11
S250
G
R
K
L
R
L
L
S
G
Y
L
W
P
R
G
Site 12
Y252
K
L
R
L
L
S
G
Y
L
W
P
R
G
S
P
Site 13
S301
T
E
K
A
P
W
N
S
L
A
W
T
V
T
S
Site 14
T323
Q
G
G
G
T
G
S
T
G
F
V
S
N
L
R
Site 15
T341
W
I
R
V
Q
Q
F
T
S
R
R
V
E
L
L
Site 16
S357
F
S
H
L
H
E
L
S
L
R
W
H
L
G
R
Site 17
T366
R
W
H
L
G
R
R
T
G
E
V
L
R
I
A
Site 18
S378
R
I
A
D
R
G
T
S
S
V
T
G
L
L
S
Site 19
T444
K
F
R
R
A
M
N
T
Q
E
N
A
T
R
A
Site 20
T449
M
N
T
Q
E
N
A
T
R
A
R
A
V
D
S
Site 21
S456
T
R
A
R
A
V
D
S
L
L
N
F
E
T
V
Site 22
T462
D
S
L
L
N
F
E
T
V
K
Y
Y
N
A
E
Site 23
Y465
L
N
F
E
T
V
K
Y
Y
N
A
E
S
Y
E
Site 24
Y466
N
F
E
T
V
K
Y
Y
N
A
E
S
Y
E
V
Site 25
S470
V
K
Y
Y
N
A
E
S
Y
E
V
E
R
Y
R
Site 26
Y476
E
S
Y
E
V
E
R
Y
R
E
A
I
I
K
Y
Site 27
Y483
Y
R
E
A
I
I
K
Y
Q
G
L
E
W
K
S
Site 28
S493
L
E
W
K
S
S
A
S
L
V
L
L
N
Q
T
Site 29
S598
E
F
E
N
V
H
F
S
Y
A
D
G
R
E
T
Site 30
T605
S
Y
A
D
G
R
E
T
L
Q
D
V
S
F
T
Site 31
S610
R
E
T
L
Q
D
V
S
F
T
V
M
P
G
Q
Site 32
T618
F
T
V
M
P
G
Q
T
L
A
L
V
G
P
S
Site 33
S655
R
I
D
G
Q
D
I
S
Q
V
T
Q
A
S
L
Site 34
T679
D
T
V
L
F
N
D
T
I
A
D
N
I
R
Y
Site 35
Y686
T
I
A
D
N
I
R
Y
G
R
V
T
A
G
N
Site 36
T690
N
I
R
Y
G
R
V
T
A
G
N
D
E
V
E
Site 37
T718
A
F
P
E
G
Y
R
T
Q
V
G
E
R
G
L
Site 38
S728
G
E
R
G
L
K
L
S
G
G
E
K
Q
R
V
Site 39
S755
I
L
L
D
E
A
T
S
A
L
D
T
S
N
E
Site 40
T759
E
A
T
S
A
L
D
T
S
N
E
R
A
I
Q
Site 41
S760
A
T
S
A
L
D
T
S
N
E
R
A
I
Q
A
Site 42
S768
N
E
R
A
I
Q
A
S
L
A
K
V
C
A
N
Site 43
S813
G
R
H
E
A
L
L
S
R
G
G
V
Y
A
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation