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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR6
Full Name:
WD repeat-containing protein 6
Alias:
Type:
Mass (Da):
121725
Number AA:
1121
UniProt ID:
Q9NNW5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
D
A
L
E
D
Y
V
W
P
R
A
T
S
Site 2
Y42
E
G
P
D
V
L
V
Y
S
L
D
F
G
G
H
Site 3
T155
I
L
Q
E
V
P
C
T
D
R
C
T
L
S
S
Site 4
S228
K
G
L
L
A
T
A
S
E
D
R
S
V
R
I
Site 5
S232
A
T
A
S
E
D
R
S
V
R
I
W
K
V
G
Site 6
Y270
Q
V
K
L
L
E
N
Y
L
I
S
A
G
E
D
Site 7
Y332
W
H
L
V
G
R
G
Y
R
G
L
G
V
S
A
Site 8
S338
G
Y
R
G
L
G
V
S
A
L
C
F
K
S
R
Site 9
S344
V
S
A
L
C
F
K
S
R
S
R
P
G
T
L
Site 10
S346
A
L
C
F
K
S
R
S
R
P
G
T
L
K
A
Site 11
T350
K
S
R
S
R
P
G
T
L
K
A
V
T
L
A
Site 12
S392
L
E
D
K
H
F
Q
S
Y
C
L
L
E
A
A
Site 13
T432
P
T
A
A
V
D
Q
T
L
F
P
G
K
V
H
Site 14
S442
P
G
K
V
H
S
L
S
W
A
L
R
G
Y
E
Site 15
Y484
F
V
K
E
R
C
R
Y
L
L
P
P
S
K
Q
Site 16
T495
P
S
K
Q
R
W
H
T
C
S
A
F
L
P
P
Site 17
S514
V
C
G
D
R
R
G
S
V
L
L
F
P
S
R
Site 18
S545
A
G
A
P
V
V
G
S
G
S
S
G
G
G
N
Site 19
T562
T
G
L
G
P
V
S
T
L
P
S
L
H
G
K
Site 20
S565
G
P
V
S
T
L
P
S
L
H
G
K
Q
G
V
Site 21
Y581
S
V
T
C
H
G
G
Y
V
Y
T
T
G
R
D
Site 22
Y583
T
C
H
G
G
Y
V
Y
T
T
G
R
D
G
A
Site 23
T585
H
G
G
Y
V
Y
T
T
G
R
D
G
A
Y
Y
Site 24
Y591
T
T
G
R
D
G
A
Y
Y
Q
L
F
V
R
D
Site 25
Y592
T
G
R
D
G
A
Y
Y
Q
L
F
V
R
D
G
Site 26
S659
N
C
G
G
G
H
R
S
W
A
F
S
D
T
E
Site 27
S663
G
H
R
S
W
A
F
S
D
T
E
A
A
M
A
Site 28
T665
R
S
W
A
F
S
D
T
E
A
A
M
A
F
A
Site 29
Y682
K
D
G
D
V
M
L
Y
R
A
L
G
G
C
T
Site 30
T705
G
L
H
G
R
E
I
T
C
V
K
R
V
G
T
Site 31
S723
G
P
E
Y
G
V
P
S
F
M
Q
P
D
D
L
Site 32
S734
P
D
D
L
E
P
G
S
E
G
P
D
L
T
D
Site 33
T787
V
A
V
W
G
I
G
T
P
G
G
P
Q
D
P
Site 34
T799
Q
D
P
Q
P
G
L
T
A
H
V
V
S
A
G
Site 35
T819
H
C
F
S
I
M
V
T
P
D
P
S
T
P
S
Site 36
T824
M
V
T
P
D
P
S
T
P
S
R
L
A
C
H
Site 37
Y843
S
S
H
R
L
D
E
Y
W
D
R
Q
R
N
R
Site 38
Y862
K
V
D
P
E
T
R
Y
M
S
L
A
V
C
E
Site 39
S864
D
P
E
T
R
Y
M
S
L
A
V
C
E
L
D
Site 40
S918
R
C
V
L
K
V
H
S
F
T
H
E
A
P
N
Site 41
S934
R
R
R
L
L
L
C
S
A
A
T
D
G
S
L
Site 42
S954
T
T
M
L
D
H
D
S
T
V
L
E
P
P
V
Site 43
T955
T
M
L
D
H
D
S
T
V
L
E
P
P
V
D
Site 44
Y967
P
V
D
P
G
L
P
Y
R
L
G
T
P
S
L
Site 45
S973
P
Y
R
L
G
T
P
S
L
T
L
Q
A
H
S
Site 46
T975
R
L
G
T
P
S
L
T
L
Q
A
H
S
C
G
Site 47
S985
A
H
S
C
G
I
N
S
L
H
T
L
P
T
R
Site 48
S1000
E
G
H
H
L
V
A
S
G
S
E
D
G
S
L
Site 49
S1002
H
H
L
V
A
S
G
S
E
D
G
S
L
H
V
Site 50
Y1038
Q
L
R
V
L
E
E
Y
S
V
P
C
A
H
A
Site 51
T1069
A
S
I
D
Q
R
L
T
F
W
R
L
G
H
G
Site 52
T1079
R
L
G
H
G
E
P
T
F
M
N
S
T
V
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation