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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PTPRH
Full Name:
Receptor-type tyrosine-protein phosphatase H
Alias:
SAP-1
Type:
Protein-tyrosine phosphatase, receptor
Mass (Da):
122353
Number AA:
1115
UniProt ID:
Q9HD43
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005001
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0006470
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T292
N
S
S
V
E
I
V
T
S
A
T
A
P
N
P
Site 2
T522
E
G
M
T
D
P
R
T
Q
S
T
S
G
T
D
Site 3
S795
E
L
R
D
L
V
F
S
S
P
G
D
I
P
A
Site 4
S796
L
R
D
L
V
F
S
S
P
G
D
I
P
A
E
Site 5
S816
V
R
K
N
E
R
D
S
N
C
G
F
A
D
E
Site 6
Y824
N
C
G
F
A
D
E
Y
Q
Q
L
S
L
V
G
Site 7
S828
A
D
E
Y
Q
Q
L
S
L
V
G
H
S
Q
S
Site 8
S835
S
L
V
G
H
S
Q
S
Q
M
V
A
S
A
S
Site 9
S842
S
Q
M
V
A
S
A
S
E
N
N
A
K
N
R
Site 10
Y850
E
N
N
A
K
N
R
Y
R
N
V
L
P
Y
D
Site 11
Y856
R
Y
R
N
V
L
P
Y
D
W
S
R
V
P
L
Site 12
S859
N
V
L
P
Y
D
W
S
R
V
P
L
K
P
I
Site 13
S872
P
I
H
E
E
P
G
S
D
Y
I
N
A
S
F
Site 14
Y874
H
E
E
P
G
S
D
Y
I
N
A
S
F
M
P
Site 15
S878
G
S
D
Y
I
N
A
S
F
M
P
G
L
W
S
Site 16
T892
S
P
Q
E
F
I
A
T
Q
G
P
L
P
Q
T
Site 17
T899
T
Q
G
P
L
P
Q
T
V
G
D
F
W
R
L
Site 18
T914
V
W
E
Q
Q
S
H
T
L
V
M
L
T
N
C
Site 19
Y932
G
R
V
K
C
E
H
Y
W
P
L
D
S
Q
P
Site 20
T941
P
L
D
S
Q
P
C
T
H
G
H
L
R
V
T
Site 21
T973
L
Q
V
E
E
Q
K
T
L
S
V
R
Q
F
H
Site 22
S975
V
E
E
Q
K
T
L
S
V
R
Q
F
H
Y
Q
Site 23
Y981
L
S
V
R
Q
F
H
Y
Q
A
W
P
D
H
G
Site 24
S991
W
P
D
H
G
V
P
S
S
P
D
T
L
L
A
Site 25
S992
P
D
H
G
V
P
S
S
P
D
T
L
L
A
F
Site 26
T1010
L
R
Q
W
L
D
Q
T
M
E
G
G
P
P
I
Site 27
S1050
E
G
L
L
G
P
F
S
F
V
R
K
M
R
E
Site 28
S1058
F
V
R
K
M
R
E
S
R
P
L
M
V
Q
T
Site 29
T1065
S
R
P
L
M
V
Q
T
E
A
Q
Y
V
F
L
Site 30
Y1069
M
V
Q
T
E
A
Q
Y
V
F
L
H
Q
C
I
Site 31
S1083
I
L
R
F
L
Q
Q
S
A
Q
A
P
A
E
K
Site 32
Y1094
P
A
E
K
E
V
P
Y
E
D
V
E
N
L
I
Site 33
Y1102
E
D
V
E
N
L
I
Y
E
N
V
A
A
I
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation