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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRPC7
Full Name:
Short transient receptor potential channel 7
Alias:
TRP7
Type:
Membrane protein
Mass (Da):
99562
Number AA:
862
UniProt ID:
Q9HCX4
International Prot ID:
IPI00030930
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005262
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Short transient receptor potential channel 7 pan-specific antibody AB-NN351-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN351-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
K
N
M
Q
R
R
H
T
T
L
R
E
K
G
R
Site 2
T16
N
M
Q
R
R
H
T
T
L
R
E
K
G
R
R
Site 3
Y31
Q
A
I
R
G
P
A
Y
M
F
N
E
K
G
T
Site 4
S39
M
F
N
E
K
G
T
S
L
T
P
E
E
E
R
Site 5
T41
N
E
K
G
T
S
L
T
P
E
E
E
R
F
L
Site 6
Y53
R
F
L
D
S
A
E
Y
G
N
I
P
V
V
R
Site 7
T68
K
M
L
E
E
S
K
T
L
N
F
N
C
V
D
Site 8
Y76
L
N
F
N
C
V
D
Y
M
G
Q
N
A
L
Q
Site 9
T138
F
A
Q
G
Q
R
L
T
L
S
P
L
E
Q
E
Site 10
S140
Q
G
Q
R
L
T
L
S
P
L
E
Q
E
L
R
Site 11
Y152
E
L
R
D
D
D
F
Y
A
Y
D
E
D
G
T
Site 12
Y154
R
D
D
D
F
Y
A
Y
D
E
D
G
T
R
F
Site 13
S162
D
E
D
G
T
R
F
S
H
D
I
T
P
I
I
Site 14
S211
T
E
K
Q
R
K
D
S
F
S
H
S
R
S
R
Site 15
S213
K
Q
R
K
D
S
F
S
H
S
R
S
R
M
N
Site 16
S215
R
K
D
S
F
S
H
S
R
S
R
M
N
A
Y
Site 17
S217
D
S
F
S
H
S
R
S
R
M
N
A
Y
K
G
Site 18
Y222
S
R
S
R
M
N
A
Y
K
G
L
A
S
A
A
Site 19
Y230
K
G
L
A
S
A
A
Y
L
S
L
S
S
E
D
Site 20
Y263
E
T
E
F
K
N
D
Y
R
K
L
S
M
Q
C
Site 21
S267
K
N
D
Y
R
K
L
S
M
Q
C
K
D
F
V
Site 22
S307
W
S
D
H
H
R
P
S
L
S
R
I
K
L
A
Site 23
S309
D
H
H
R
P
S
L
S
R
I
K
L
A
I
K
Site 24
Y337
Q
Q
L
L
T
M
W
Y
E
N
L
S
G
L
R
Site 25
S375
A
Y
W
I
A
P
C
S
K
L
G
R
T
L
R
Site 26
T380
P
C
S
K
L
G
R
T
L
R
S
P
F
M
K
Site 27
S383
K
L
G
R
T
L
R
S
P
F
M
K
F
V
A
Site 28
T415
D
R
F
E
G
V
K
T
L
P
N
E
T
F
T
Site 29
T420
V
K
T
L
P
N
E
T
F
T
D
Y
P
K
Q
Site 30
T422
T
L
P
N
E
T
F
T
D
Y
P
K
Q
I
F
Site 31
Y424
P
N
E
T
F
T
D
Y
P
K
Q
I
F
R
V
Site 32
T433
K
Q
I
F
R
V
K
T
T
Q
F
S
W
T
E
Site 33
Y466
W
E
E
G
P
R
E
Y
V
L
H
L
W
N
L
Site 34
Y502
K
A
T
E
A
Q
L
Y
V
D
Q
H
V
Q
D
Site 35
T511
D
Q
H
V
Q
D
D
T
L
H
N
V
S
L
P
Site 36
Y523
S
L
P
P
E
V
A
Y
F
T
Y
A
R
D
K
Site 37
S534
A
R
D
K
W
W
P
S
D
P
Q
I
I
S
E
Site 38
Y557
L
S
F
S
R
I
A
Y
I
L
P
A
N
E
S
Site 39
S571
S
F
G
P
L
Q
I
S
L
G
R
T
V
K
D
Site 40
Y601
M
I
G
M
F
N
L
Y
S
Y
Y
R
G
A
K
Site 41
Y603
G
M
F
N
L
Y
S
Y
Y
R
G
A
K
Y
N
Site 42
Y609
S
Y
Y
R
G
A
K
Y
N
P
A
F
T
T
V
Site 43
T615
K
Y
N
P
A
F
T
T
V
E
E
S
F
K
T
Site 44
S675
L
I
A
M
I
N
N
S
Y
Q
E
I
E
E
D
Site 45
S697
A
R
A
K
L
W
L
S
Y
F
D
E
G
R
T
Site 46
Y698
R
A
K
L
W
L
S
Y
F
D
E
G
R
T
L
Site 47
S714
A
P
F
N
L
V
P
S
P
K
S
F
Y
Y
L
Site 48
S717
N
L
V
P
S
P
K
S
F
Y
Y
L
I
M
R
Site 49
Y720
P
S
P
K
S
F
Y
Y
L
I
M
R
I
K
M
Site 50
S739
L
C
K
S
K
A
K
S
C
E
N
D
L
E
M
Site 51
S751
L
E
M
G
M
L
N
S
K
F
K
K
T
R
Y
Site 52
Y758
S
K
F
K
K
T
R
Y
Q
A
G
M
R
N
S
Site 53
S765
Y
Q
A
G
M
R
N
S
E
N
L
T
A
N
N
Site 54
T769
M
R
N
S
E
N
L
T
A
N
N
T
L
S
K
Site 55
T773
E
N
L
T
A
N
N
T
L
S
K
P
T
R
Y
Site 56
S775
L
T
A
N
N
T
L
S
K
P
T
R
Y
Q
K
Site 57
Y791
M
K
R
L
I
K
R
Y
V
L
K
A
Q
V
D
Site 58
S818
E
I
K
Q
D
I
S
S
L
R
Y
E
L
L
E
Site 59
Y821
Q
D
I
S
S
L
R
Y
E
L
L
E
E
K
S
Site 60
S828
Y
E
L
L
E
E
K
S
Q
A
T
G
E
L
A
Site 61
S842
A
D
L
I
Q
Q
L
S
E
K
F
G
K
N
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation