PhosphoNET

           
Protein Info 
   
Short Name:  FGF22
Full Name:  Fibroblast growth factor 22
Alias:  UNQ2500/PRO5800
Type:  Secreted protein
Mass (Da):  19663
Number AA:  170
UniProt ID:  Q9HCT0
International Prot ID:  IPI00030814
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005615     Uniprot OncoNet
Molecular Function:  GO:0008083     PhosphoSite+ KinaseNET
Biological Process:  GO:0030154  GO:0008543   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T23RAPDAAGTPSASRGP
Site 2S25PDAAGTPSASRGPRS
Site 3S27AAGTPSASRGPRSYP
Site 4S32SASRGPRSYPHLEGD
Site 5Y33ASRGPRSYPHLEGDV
Site 6S47VRWRRLFSSTHFFLR
Site 7S48RWRRLFSSTHFFLRV
Site 8T49WRRLFSSTHFFLRVD
Site 9T64PGGRVQGTRWRHGQD
Site 10S72RWRHGQDSILEIRSV
Site 11Y94KAVSSGFYVAMNRRG
Site 12Y104MNRRGRLYGSRLYTV
Site 13Y109RLYGSRLYTVDCRFR
Site 14T110LYGSRLYTVDCRFRE
Site 15Y127EENGHNTYASQRWRR
Site 16T155GPRPGGRTRRYHLSA
Site 17Y158PGGRTRRYHLSAHFL
Site 18S161RTRRYHLSAHFLPVL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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