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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM8A
Full Name:
Transmembrane protein 8A
Alias:
Protein M83;Transmembrane protein 6;Transmembrane protein 8
Type:
Mass (Da):
84761
Number AA:
771
UniProt ID:
Q9HCN3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
G
R
A
G
T
G
T
G
G
E
A
V
Site 2
S33
L
A
R
P
P
P
A
S
A
G
Y
S
G
K
S
Site 3
S37
P
P
A
S
A
G
Y
S
G
K
S
E
V
G
L
Site 4
S40
S
A
G
Y
S
G
K
S
E
V
G
L
V
S
E
Site 5
S46
K
S
E
V
G
L
V
S
E
H
F
S
Q
A
P
Site 6
S50
G
L
V
S
E
H
F
S
Q
A
P
Q
R
L
S
Site 7
S57
S
Q
A
P
Q
R
L
S
F
Y
S
W
Y
G
S
Site 8
Y59
A
P
Q
R
L
S
F
Y
S
W
Y
G
S
A
R
Site 9
S60
P
Q
R
L
S
F
Y
S
W
Y
G
S
A
R
L
Site 10
Y62
R
L
S
F
Y
S
W
Y
G
S
A
R
L
F
R
Site 11
S89
L
L
Q
V
S
R
E
S
G
A
A
C
T
D
A
Site 12
T121
G
T
S
F
P
D
D
T
A
V
Q
P
S
F
Q
Site 13
S134
F
Q
V
G
V
P
L
S
T
A
P
R
S
N
A
Site 14
T135
Q
V
G
V
P
L
S
T
A
P
R
S
N
A
S
Site 15
S139
P
L
S
T
A
P
R
S
N
A
S
V
N
V
S
Site 16
S142
T
A
P
R
S
N
A
S
V
N
V
S
H
P
A
Site 17
S146
S
N
A
S
V
N
V
S
H
P
A
P
G
D
W
Site 18
S162
V
A
A
H
L
P
P
S
S
Q
K
I
E
L
K
Site 19
S163
A
A
H
L
P
P
S
S
Q
K
I
E
L
K
G
Site 20
T203
P
D
V
P
L
P
Q
T
L
L
S
H
P
S
Y
Site 21
S206
P
L
P
Q
T
L
L
S
H
P
S
Y
L
K
V
Site 22
S231
L
E
L
R
D
C
V
S
N
G
S
L
G
C
P
Site 23
T247
R
L
T
V
G
P
V
T
L
P
S
N
F
Q
K
Site 24
T257
S
N
F
Q
K
V
L
T
C
T
G
A
P
W
P
Site 25
S271
P
C
R
L
L
L
P
S
P
P
W
D
R
W
L
Site 26
T281
W
D
R
W
L
Q
V
T
A
E
S
L
V
G
P
Site 27
T309
A
C
R
P
R
S
V
T
V
Q
P
L
L
Q
S
Site 28
S317
V
Q
P
L
L
Q
S
S
Q
N
Q
S
F
N
A
Site 29
S321
L
Q
S
S
Q
N
Q
S
F
N
A
S
S
G
L
Site 30
S325
Q
N
Q
S
F
N
A
S
S
G
L
L
S
P
S
Site 31
S326
N
Q
S
F
N
A
S
S
G
L
L
S
P
S
P
Site 32
S330
N
A
S
S
G
L
L
S
P
S
P
D
H
Q
D
Site 33
S332
S
S
G
L
L
S
P
S
P
D
H
Q
D
L
G
Site 34
S347
R
S
G
R
V
D
R
S
P
F
C
L
T
N
Y
Site 35
T352
D
R
S
P
F
C
L
T
N
Y
P
V
T
R
E
Site 36
Y354
S
P
F
C
L
T
N
Y
P
V
T
R
E
D
M
Site 37
S365
R
E
D
M
D
V
V
S
V
H
F
Q
P
L
D
Site 38
S375
F
Q
P
L
D
R
V
S
V
R
V
C
S
D
T
Site 39
S380
R
V
S
V
R
V
C
S
D
T
P
S
V
M
R
Site 40
T382
S
V
R
V
C
S
D
T
P
S
V
M
R
L
R
Site 41
S384
R
V
C
S
D
T
P
S
V
M
R
L
R
L
N
Site 42
T392
V
M
R
L
R
L
N
T
G
M
D
S
G
G
S
Site 43
S396
R
L
N
T
G
M
D
S
G
G
S
L
T
I
S
Site 44
S399
T
G
M
D
S
G
G
S
L
T
I
S
L
R
A
Site 45
S403
S
G
G
S
L
T
I
S
L
R
A
N
K
T
E
Site 46
T409
I
S
L
R
A
N
K
T
E
M
R
N
E
T
V
Site 47
T415
K
T
E
M
R
N
E
T
V
V
V
A
C
V
N
Site 48
S447
F
F
Q
G
Y
P
L
S
L
S
A
W
S
R
R
Site 49
S449
Q
G
Y
P
L
S
L
S
A
W
S
R
R
A
N
Site 50
Y461
R
A
N
L
I
I
P
Y
P
E
T
D
N
W
Y
Site 51
Y468
Y
P
E
T
D
N
W
Y
L
S
L
Q
L
M
C
Site 52
Y518
L
R
R
H
S
Y
L
Y
A
S
C
S
C
K
A
Site 53
T540
T
D
N
S
T
A
Q
T
V
A
Q
Q
R
A
A
Site 54
Y608
L
S
Y
D
T
L
Q
Y
C
D
F
L
G
S
G
Site 55
Y757
S
Q
K
F
P
C
H
Y
Q
I
C
K
N
D
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation