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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MSL2L1
Full Name:
Male-specific lethal 2 homolog
Alias:
FLJ10546; KIAA1585; Male-specific lethal 2; Male-specific lethal 2-like 1; Male-specific lethal-2; MSL2; MSL-2; MSL2-like 1; RING finger protein 184; RNF184
Type:
Mass (Da):
62540
Number AA:
UniProt ID:
Q9HCI7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
N
A
T
A
L
Y
I
S
A
S
R
L
V
L
N
Site 2
Y20
A
S
R
L
V
L
N
Y
D
P
G
D
P
K
A
Site 3
T29
P
G
D
P
K
A
F
T
E
I
N
R
L
L
P
Site 4
Y37
E
I
N
R
L
L
P
Y
F
R
Q
S
L
S
C
Site 5
T58
L
Q
D
P
I
A
P
T
N
S
T
C
Q
H
Y
Site 6
Y87
S
C
S
W
C
K
D
Y
E
Q
F
E
E
N
K
Site 7
T114
C
E
Y
I
T
Q
T
T
L
A
R
D
I
I
E
Site 8
T143
G
S
L
F
C
E
E
T
E
K
P
S
D
S
S
Site 9
S147
C
E
E
T
E
K
P
S
D
S
S
F
T
L
C
Site 10
S149
E
T
E
K
P
S
D
S
S
F
T
L
C
L
T
Site 11
S150
T
E
K
P
S
D
S
S
F
T
L
C
L
T
H
Site 12
T152
K
P
S
D
S
S
F
T
L
C
L
T
H
S
P
Site 13
S158
F
T
L
C
L
T
H
S
P
L
P
S
T
S
E
Site 14
S162
L
T
H
S
P
L
P
S
T
S
E
P
T
T
D
Site 15
T163
T
H
S
P
L
P
S
T
S
E
P
T
T
D
P
Site 16
S164
H
S
P
L
P
S
T
S
E
P
T
T
D
P
Q
Site 17
T168
P
S
T
S
E
P
T
T
D
P
Q
A
S
L
S
Site 18
S173
P
T
T
D
P
Q
A
S
L
S
P
M
S
E
S
Site 19
S175
T
D
P
Q
A
S
L
S
P
M
S
E
S
T
L
Site 20
S178
Q
A
S
L
S
P
M
S
E
S
T
L
S
I
A
Site 21
Y197
V
I
N
G
L
P
T
Y
N
G
L
S
I
D
R
Site 22
S201
L
P
T
Y
N
G
L
S
I
D
R
F
G
I
N
Site 23
S211
R
F
G
I
N
I
P
S
P
E
H
S
N
T
I
Site 24
T217
P
S
P
E
H
S
N
T
I
D
V
C
N
T
V
Site 25
T228
C
N
T
V
D
I
K
T
E
D
L
S
D
S
L
Site 26
S232
D
I
K
T
E
D
L
S
D
S
L
P
P
V
C
Site 27
S234
K
T
E
D
L
S
D
S
L
P
P
V
C
D
T
Site 28
S255
S
T
G
I
D
I
C
S
F
S
E
D
I
K
P
Site 29
S257
G
I
D
I
C
S
F
S
E
D
I
K
P
G
D
Site 30
S265
E
D
I
K
P
G
D
S
L
L
L
S
V
E
E
Site 31
S276
S
V
E
E
V
L
R
S
L
E
T
V
S
N
T
Site 32
T279
E
V
L
R
S
L
E
T
V
S
N
T
E
V
C
Site 33
S281
L
R
S
L
E
T
V
S
N
T
E
V
C
C
P
Site 34
T297
L
Q
P
N
L
E
A
T
V
S
N
G
P
F
L
Site 35
S299
P
N
L
E
A
T
V
S
N
G
P
F
L
Q
L
Site 36
S307
N
G
P
F
L
Q
L
S
S
Q
S
L
S
H
N
Site 37
S308
G
P
F
L
Q
L
S
S
Q
S
L
S
H
N
V
Site 38
S312
Q
L
S
S
Q
S
L
S
H
N
V
F
M
S
T
Site 39
S327
S
P
A
L
H
G
L
S
C
T
A
A
T
P
K
Site 40
S343
A
K
L
N
R
K
R
S
R
S
E
S
D
S
E
Site 41
S345
L
N
R
K
R
S
R
S
E
S
D
S
E
K
V
Site 42
S347
R
K
R
S
R
S
E
S
D
S
E
K
V
Q
P
Site 43
S349
R
S
R
S
E
S
D
S
E
K
V
Q
P
L
P
Site 44
S369
R
G
P
T
L
G
A
S
A
P
V
T
V
K
R
Site 45
T373
L
G
A
S
A
P
V
T
V
K
R
E
S
K
I
Site 46
S378
P
V
T
V
K
R
E
S
K
I
S
L
Q
P
I
Site 47
S381
V
K
R
E
S
K
I
S
L
Q
P
I
A
T
V
Site 48
T394
T
V
P
N
G
G
T
T
P
K
I
S
K
T
V
Site 49
S398
G
G
T
T
P
K
I
S
K
T
V
L
L
S
T
Site 50
T400
T
T
P
K
I
S
K
T
V
L
L
S
T
K
S
Site 51
S404
I
S
K
T
V
L
L
S
T
K
S
M
K
K
S
Site 52
T405
S
K
T
V
L
L
S
T
K
S
M
K
K
S
H
Site 53
S407
T
V
L
L
S
T
K
S
M
K
K
S
H
E
H
Site 54
S411
S
T
K
S
M
K
K
S
H
E
H
G
S
K
K
Site 55
S416
K
K
S
H
E
H
G
S
K
K
S
H
S
K
T
Site 56
S419
H
E
H
G
S
K
K
S
H
S
K
T
K
P
G
Site 57
S421
H
G
S
K
K
S
H
S
K
T
K
P
G
I
L
Site 58
T423
S
K
K
S
H
S
K
T
K
P
G
I
L
K
K
Site 59
S440
A
V
K
E
K
I
P
S
H
H
F
M
P
G
S
Site 60
S447
S
H
H
F
M
P
G
S
P
T
K
T
V
Y
K
Site 61
T449
H
F
M
P
G
S
P
T
K
T
V
Y
K
K
P
Site 62
T451
M
P
G
S
P
T
K
T
V
Y
K
K
P
Q
E
Site 63
Y453
G
S
P
T
K
T
V
Y
K
K
P
Q
E
K
K
Site 64
T468
G
C
K
C
G
R
A
T
Q
N
P
S
V
L
T
Site 65
Y484
R
G
Q
R
C
P
C
Y
S
N
R
K
A
C
L
Site 66
Y502
C
R
G
C
Q
N
S
Y
M
A
N
G
E
K
K
Site 67
S540
S
I
A
V
R
N
A
S
T
S
T
S
V
I
N
Site 68
S544
R
N
A
S
T
S
T
S
V
I
N
V
T
G
S
Site 69
S560
V
T
T
F
L
A
A
S
T
H
D
D
K
S
L
Site 70
T561
T
T
F
L
A
A
S
T
H
D
D
K
S
L
D
Site 71
S566
A
S
T
H
D
D
K
S
L
D
E
A
I
D
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation