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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
METTL14
Full Name:
Methyltransferase-like protein 14
Alias:
Type:
Mass (Da):
52150
Number AA:
456
UniProt ID:
Q9HCE5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S37
S
I
G
A
V
L
N
S
K
D
E
Q
R
E
I
Site 2
T47
E
Q
R
E
I
A
E
T
R
E
T
C
R
A
S
Site 3
T50
E
I
A
E
T
R
E
T
C
R
A
S
Y
D
T
Site 4
S54
T
R
E
T
C
R
A
S
Y
D
T
S
A
P
N
Site 5
Y55
R
E
T
C
R
A
S
Y
D
T
S
A
P
N
A
Site 6
T57
T
C
R
A
S
Y
D
T
S
A
P
N
A
K
R
Site 7
S58
C
R
A
S
Y
D
T
S
A
P
N
A
K
R
K
Site 8
Y66
A
P
N
A
K
R
K
Y
L
D
E
G
E
T
D
Site 9
Y95
Q
D
E
E
N
L
P
Y
E
E
E
I
Y
K
D
Site 10
Y100
L
P
Y
E
E
E
I
Y
K
D
S
S
T
F
L
Site 11
S104
E
E
I
Y
K
D
S
S
T
F
L
K
G
T
Q
Site 12
T105
E
I
Y
K
D
S
S
T
F
L
K
G
T
Q
S
Site 13
T110
S
S
T
F
L
K
G
T
Q
S
L
N
P
H
N
Site 14
S112
T
F
L
K
G
T
Q
S
L
N
P
H
N
D
Y
Site 15
Y119
S
L
N
P
H
N
D
Y
C
Q
H
F
V
D
T
Site 16
Y146
L
A
D
R
F
E
E
Y
P
K
L
R
E
L
I
Site 17
S163
K
D
E
L
I
A
K
S
N
T
P
P
M
Y
L
Site 18
T165
E
L
I
A
K
S
N
T
P
P
M
Y
L
Q
A
Site 19
Y169
K
S
N
T
P
P
M
Y
L
Q
A
D
I
E
A
Site 20
Y198
L
E
P
P
L
E
E
Y
Y
R
E
T
G
I
T
Site 21
T202
L
E
E
Y
Y
R
E
T
G
I
T
A
N
E
K
Site 22
T274
N
K
N
N
P
G
K
T
K
T
L
D
P
K
A
Site 23
T295
C
L
M
G
I
K
G
T
V
K
R
S
T
D
G
Site 24
T300
K
G
T
V
K
R
S
T
D
G
D
F
I
H
A
Site 25
S351
L
H
L
F
G
R
D
S
T
I
R
P
G
W
L
Site 26
T352
H
L
F
G
R
D
S
T
I
R
P
G
W
L
T
Site 27
T363
G
W
L
T
V
G
P
T
L
T
N
S
N
Y
N
Site 28
S367
V
G
P
T
L
T
N
S
N
Y
N
A
E
T
Y
Site 29
Y369
P
T
L
T
N
S
N
Y
N
A
E
T
Y
A
S
Site 30
Y374
S
N
Y
N
A
E
T
Y
A
S
Y
F
S
A
P
Site 31
S376
Y
N
A
E
T
Y
A
S
Y
F
S
A
P
N
S
Site 32
Y377
N
A
E
T
Y
A
S
Y
F
S
A
P
N
S
Y
Site 33
S379
E
T
Y
A
S
Y
F
S
A
P
N
S
Y
L
T
Site 34
S383
S
Y
F
S
A
P
N
S
Y
L
T
G
C
T
E
Site 35
S399
I
E
R
L
R
P
K
S
P
P
P
K
S
K
S
Site 36
S404
P
K
S
P
P
P
K
S
K
S
D
R
G
G
G
Site 37
S406
S
P
P
P
K
S
K
S
D
R
G
G
G
A
P
Site 38
T421
R
G
G
G
R
G
G
T
S
A
G
R
G
R
E
Site 39
S422
G
G
G
R
G
G
T
S
A
G
R
G
R
E
R
Site 40
S432
R
G
R
E
R
N
R
S
N
F
R
G
E
R
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation