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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MCCC2
Full Name:
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial
Alias:
3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta
Type:
Mass (Da):
61315
Number AA:
563
UniProt ID:
Q9HCC0
International Prot ID:
IPI00784044
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005759
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004485
GO:0016421
PhosphoSite+
KinaseNET
Biological Process:
GO:0006082
GO:0006519
GO:0006520
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
L
R
P
C
A
R
A
S
P
A
G
P
R
A
Y
Site 2
Y23
S
P
A
G
P
R
A
Y
H
G
D
S
V
A
S
Site 3
S27
P
R
A
Y
H
G
D
S
V
A
S
L
G
T
Q
Site 4
S30
Y
H
G
D
S
V
A
S
L
G
T
Q
P
D
L
Site 5
S39
G
T
Q
P
D
L
G
S
A
L
Y
Q
E
N
Y
Site 6
Y42
P
D
L
G
S
A
L
Y
Q
E
N
Y
K
Q
M
Site 7
Y46
S
A
L
Y
Q
E
N
Y
K
Q
M
K
A
L
V
Site 8
S77
K
A
R
A
L
H
I
S
R
G
K
L
L
P
R
Site 9
S95
D
N
L
I
D
P
G
S
P
F
L
E
L
S
Q
Site 10
Y109
Q
F
A
G
Y
Q
L
Y
D
N
E
E
V
P
G
Site 11
Y145
A
T
V
K
G
G
A
Y
Y
P
V
T
V
K
K
Site 12
Y146
T
V
K
G
G
A
Y
Y
P
V
T
V
K
K
Q
Site 13
T149
G
G
A
Y
Y
P
V
T
V
K
K
Q
L
R
A
Site 14
Y169
Q
N
R
L
P
C
I
Y
L
V
D
S
G
G
A
Site 15
Y177
L
V
D
S
G
G
A
Y
L
P
R
Q
A
D
V
Site 16
Y196
D
H
F
G
R
T
F
Y
N
Q
A
I
M
S
S
Site 17
S270
A
D
L
H
C
R
K
S
G
V
S
D
H
W
A
Site 18
T303
Y
Q
K
K
L
D
V
T
I
E
P
S
E
E
P
Site 19
S328
V
G
A
N
L
K
R
S
F
D
V
R
E
V
I
Site 20
S342
I
A
R
I
V
D
G
S
R
F
T
E
F
K
A
Site 21
T345
I
V
D
G
S
R
F
T
E
F
K
A
F
Y
G
Site 22
S378
G
N
N
G
V
L
F
S
E
S
A
K
K
G
T
Site 23
S380
N
G
V
L
F
S
E
S
A
K
K
G
T
H
F
Site 24
Y413
G
F
M
V
G
R
E
Y
E
A
E
G
I
A
K
Site 25
Y445
T
L
I
I
G
G
S
Y
G
A
G
N
Y
G
M
Site 26
Y450
G
S
Y
G
A
G
N
Y
G
M
C
G
R
A
Y
Site 27
Y457
Y
G
M
C
G
R
A
Y
S
P
R
F
L
Y
I
Site 28
Y463
A
Y
S
P
R
F
L
Y
I
W
P
N
A
R
I
Site 29
S471
I
W
P
N
A
R
I
S
V
M
G
G
E
Q
A
Site 30
S499
R
E
G
K
Q
F
S
S
A
D
E
A
A
L
K
Site 31
Y520
F
E
E
E
G
N
P
Y
Y
S
S
A
R
V
W
Site 32
Y521
E
E
E
G
N
P
Y
Y
S
S
A
R
V
W
D
Site 33
S523
E
G
N
P
Y
Y
S
S
A
R
V
W
D
D
G
Site 34
T556
L
N
A
P
I
E
K
T
D
F
G
I
F
R
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation