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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CAPN10
Full Name:
Calpain-10
Alias:
Calcium-activated neutral proteinase 10
Type:
Mass (Da):
74938
Number AA:
672
UniProt ID:
Q9HC96
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
R
A
G
R
G
A
T
P
A
R
E
L
F
R
Site 2
T42
A
Q
F
R
E
D
I
T
W
R
R
P
Q
E
I
Site 3
T52
R
P
Q
E
I
C
A
T
P
R
L
F
P
D
D
Site 4
S99
V
I
P
P
G
Q
P
S
W
A
D
Q
E
Y
R
Site 5
Y105
P
S
W
A
D
Q
E
Y
R
G
S
F
T
C
R
Site 6
T123
F
G
R
W
V
E
V
T
T
D
D
R
L
P
C
Site 7
T124
G
R
W
V
E
V
T
T
D
D
R
L
P
C
L
Site 8
S138
L
A
G
R
L
C
F
S
R
C
Q
R
E
D
V
Site 9
S243
E
F
H
A
F
I
V
S
D
L
R
E
L
Q
G
Site 10
T316
L
R
E
F
D
E
L
T
V
G
Y
P
V
T
E
Site 11
Y319
F
D
E
L
T
V
G
Y
P
V
T
E
A
G
H
Site 12
S329
T
E
A
G
H
L
Q
S
L
Y
T
E
R
L
L
Site 13
Y331
A
G
H
L
Q
S
L
Y
T
E
R
L
L
C
H
Site 14
T332
G
H
L
Q
S
L
Y
T
E
R
L
L
C
H
T
Site 15
T339
T
E
R
L
L
C
H
T
R
A
L
P
G
A
W
Site 16
S359
A
G
G
C
R
N
N
S
G
F
P
S
N
P
K
Site 17
S363
R
N
N
S
G
F
P
S
N
P
K
F
W
L
R
Site 18
S372
P
K
F
W
L
R
V
S
E
P
S
E
V
Y
I
Site 19
S403
A
R
A
L
V
G
D
S
H
T
S
W
S
P
A
Site 20
S406
L
V
G
D
S
H
T
S
W
S
P
A
S
I
P
Site 21
S408
G
D
S
H
T
S
W
S
P
A
S
I
P
G
K
Site 22
S411
H
T
S
W
S
P
A
S
I
P
G
K
H
Y
Q
Site 23
Y451
A
G
T
A
C
H
A
Y
D
R
E
V
H
L
R
Site 24
Y465
R
C
E
L
S
P
G
Y
Y
L
A
V
P
S
T
Site 25
Y466
C
E
L
S
P
G
Y
Y
L
A
V
P
S
T
F
Site 26
T504
R
A
V
A
K
N
T
T
P
G
A
A
L
P
A
Site 27
T516
L
P
A
G
E
W
G
T
V
Q
L
R
G
S
W
Site 28
S522
G
T
V
Q
L
R
G
S
W
R
V
G
Q
T
A
Site 29
T528
G
S
W
R
V
G
Q
T
A
G
G
S
R
N
F
Site 30
S532
V
G
Q
T
A
G
G
S
R
N
F
A
S
Y
P
Site 31
S537
G
G
S
R
N
F
A
S
Y
P
T
N
P
C
F
Site 32
Y538
G
S
R
N
F
A
S
Y
P
T
N
P
C
F
P
Site 33
T540
R
N
F
A
S
Y
P
T
N
P
C
F
P
F
S
Site 34
S547
T
N
P
C
F
P
F
S
V
P
E
G
P
G
P
Site 35
S588
Q
V
P
E
G
G
R
S
Q
D
A
P
P
L
L
Site 36
T629
T
Y
K
V
V
P
S
T
Y
L
P
D
T
E
G
Site 37
Y630
Y
K
V
V
P
S
T
Y
L
P
D
T
E
G
A
Site 38
T634
P
S
T
Y
L
P
D
T
E
G
A
F
T
V
T
Site 39
S650
A
T
R
I
D
R
P
S
I
H
S
Q
E
M
L
Site 40
S653
I
D
R
P
S
I
H
S
Q
E
M
L
G
Q
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation