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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Slc24a3
Full Name:
Sodium/potassium/calcium exchanger 3
Alias:
Na(+)/K(+)/Ca(2+)-exchange protein 3; Nckx3; Solute carrier family 24 (sodium/potassium/calcium exchanger) member 3; Solute carrier family 24 (sodium/potassium/calcium exchanger), member 3; Solute carrier family 24 member 3
Type:
Mass (Da):
71974
Number AA:
644
UniProt ID:
Q9HC58
International Prot ID:
IPI00010272
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0030955
GO:0031402
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
GO:0006813
GO:0006814
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S41
A
L
L
L
W
S
L
S
S
L
R
E
Q
K
E
Site 2
S42
L
L
L
W
S
L
S
S
L
R
E
Q
K
E
L
Site 3
T73
K
L
M
Q
V
N
D
T
L
T
S
E
D
A
G
Site 4
T75
M
Q
V
N
D
T
L
T
S
E
D
A
G
L
R
Site 5
S84
E
D
A
G
L
R
N
S
K
N
C
T
E
P
A
Site 6
T88
L
R
N
S
K
N
C
T
E
P
A
L
H
E
F
Site 7
T101
E
F
P
N
D
I
F
T
N
E
D
R
R
Q
G
Site 8
S135
C
D
D
F
F
V
P
S
L
E
K
I
C
E
R
Site 9
Y248
S
L
V
L
V
L
M
Y
L
I
Y
I
V
I
M
Site 10
Y251
L
V
L
M
Y
L
I
Y
I
V
I
M
K
Y
N
Site 11
S288
N
N
A
E
I
D
D
S
S
N
C
D
A
T
V
Site 12
S289
N
A
E
I
D
D
S
S
N
C
D
A
T
V
V
Site 13
T294
D
S
S
N
C
D
A
T
V
V
L
L
K
K
A
Site 14
S308
A
N
F
H
R
K
A
S
V
I
M
V
D
E
L
Site 15
Y319
V
D
E
L
L
S
A
Y
P
H
Q
L
S
F
S
Site 16
S324
S
A
Y
P
H
Q
L
S
F
S
E
A
G
L
R
Site 17
S326
Y
P
H
Q
L
S
F
S
E
A
G
L
R
I
M
Site 18
S336
G
L
R
I
M
I
T
S
H
F
P
P
K
T
R
Site 19
T342
T
S
H
F
P
P
K
T
R
L
S
M
A
S
R
Site 20
S345
F
P
P
K
T
R
L
S
M
A
S
R
M
L
I
Site 21
S348
K
T
R
L
S
M
A
S
R
M
L
I
N
E
R
Site 22
Y364
R
L
I
N
S
R
A
Y
T
N
G
E
S
E
V
Site 23
T365
L
I
N
S
R
A
Y
T
N
G
E
S
E
V
A
Site 24
T380
I
K
I
P
I
K
H
T
V
E
N
G
T
G
P
Site 25
S389
E
N
G
T
G
P
S
S
A
P
D
R
G
V
N
Site 26
T398
P
D
R
G
V
N
G
T
R
R
D
D
V
V
A
Site 27
T436
D
D
D
E
G
P
Y
T
P
F
D
T
P
S
G
Site 28
T440
G
P
Y
T
P
F
D
T
P
S
G
K
L
E
T
Site 29
S572
T
L
A
V
D
Y
G
S
Y
I
R
L
N
S
R
Site 30
Y573
L
A
V
D
Y
G
S
Y
I
R
L
N
S
R
G
Site 31
S578
G
S
Y
I
R
L
N
S
R
G
L
I
Y
S
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation