PhosphoNET

           
Protein Info 
   
Short Name:  CBX8
Full Name:  Chromobox protein homolog 8
Alias:  Chromobox 8; Chromobox protein 8; HPC3; PC3; Polycomb 3; Polycomb 3 homolog; RC1; Rectachrome 1
Type:  Transcription, coactivator/corepressor
Mass (Da):  43396
Number AA:  389
UniProt ID:  Q9HC52
International Prot ID:  IPI00307659
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0000785  GO:0000785  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0003682  GO:0003824  GO:0004842 PhosphoSite+ KinaseNET
Biological Process:  GO:0006333  GO:0045449  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y28IRKGRMEYLVKWKGW
Site 2Y39WKGWSQKYSTWEPEE
Site 3T41GWSQKYSTWEPEENI
Site 4Y67REREMELYGPKKRGP
Site 5T78KRGPKPKTFLLKAQA
Site 6T91QAKAKAKTYEFRSDS
Site 7Y92AKAKAKTYEFRSDSA
Site 8S96AKTYEFRSDSARGIR
Site 9S98TYEFRSDSARGIRIP
Site 10Y106ARGIRIPYPGRSPQD
Site 11S110RIPYPGRSPQDLAST
Site 12S116RSPQDLASTSRAREG
Site 13S118PQDLASTSRAREGLR
Site 14S130GLRNMGLSPPASSTS
Site 15S134MGLSPPASSTSTSST
Site 16S135GLSPPASSTSTSSTC
Site 17T136LSPPASSTSTSSTCR
Site 18S137SPPASSTSTSSTCRA
Site 19T138PPASSTSTSSTCRAE
Site 20S139PASSTSTSSTCRAEA
Site 21S140ASSTSTSSTCRAEAP
Site 22T141SSTSTSSTCRAEAPR
Site 23T182ERERERGTSRVDDKP
Site 24S183RERERGTSRVDDKPS
Site 25S190SRVDDKPSSPGDSSK
Site 26S191RVDDKPSSPGDSSKK
Site 27S195KPSSPGDSSKKRGPK
Site 28S196PSSPGDSSKKRGPKP
Site 29S211RKELPDPSQRPLGEP
Site 30Y225PSAGLGEYLKGRKLD
Site 31T234KGRKLDDTPSGAGKF
Site 32S236RKLDDTPSGAGKFPA
Site 33S246GKFPAGHSVIQLARR
Site 34S256QLARRQDSDLVQCGV
Site 35T264DLVQCGVTSPSSAEA
Site 36S265LVQCGVTSPSSAEAT
Site 37S268CGVTSPSSAEATGKL
Site 38T305GALDPNGTRVRHGSG
Site 39S311GTRVRHGSGPPSSGG
Site 40S315RHGSGPPSSGGGLYR
Site 41S316HGSGPPSSGGGLYRD
Site 42Y321PSSGGGLYRDMGAQG
Site 43S332GAQGGRPSLIARIPV
Site 44S350LGDPEEESWSPSLTN
Site 45S352DPEEESWSPSLTNLE
Site 46S354EEESWSPSLTNLEKV
Site 47T356ESWSPSLTNLEKVVV
Site 48T372DVTSNFLTVTIKESN
Site 49T374TSNFLTVTIKESNTD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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