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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SGK2
Full Name:
Serine/threonine-protein kinase Sgk2
Alias:
EC 2.7.11.1; Sgk2
Type:
Protein-serine kinase, AGC group, SGK family
Mass (Da):
47604
Number AA:
427
UniProt ID:
Q9HBY8
International Prot ID:
IPI00217154
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0015459
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0006468
GO:0007243
GO:0006979
Phosida
TranscriptoNet
STRING
Kinexus Products
GSK3b (4-10) KinSub - Glycogen synthase kinase-3-beta-derived N-terminus (R4-F10, human) peptide; Akt1 protein kinase substrate peptide - Powder PE-01ACU95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01ACU95
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
Q
G
L
L
T
S
G
R
K
P
S
G
Site 2
S7
_
M
Q
G
L
L
T
S
G
R
K
P
S
G
G
Site 3
S12
L
T
S
G
R
K
P
S
G
G
G
R
C
T
G
Site 4
T18
P
S
G
G
G
R
C
T
G
R
G
G
W
R
G
Site 5
Y59
P
E
L
P
D
H
C
Y
R
M
N
S
S
P
A
Site 6
S63
D
H
C
Y
R
M
N
S
S
P
A
G
T
P
S
Site 7
S64
H
C
Y
R
M
N
S
S
P
A
G
T
P
S
P
Site 8
T68
M
N
S
S
P
A
G
T
P
S
P
Q
P
S
R
Site 9
S70
S
S
P
A
G
T
P
S
P
Q
P
S
R
A
N
Site 10
S74
G
T
P
S
P
Q
P
S
R
A
N
G
N
I
N
Site 11
Y121
R
K
S
D
G
A
F
Y
A
V
K
V
L
Q
K
Site 12
S130
V
K
V
L
Q
K
K
S
I
L
K
K
K
E
Q
Site 13
S145
S
H
I
M
A
E
R
S
V
L
L
K
N
V
R
Site 14
Y161
P
F
L
V
G
L
R
Y
S
F
Q
T
P
E
K
Site 15
S162
F
L
V
G
L
R
Y
S
F
Q
T
P
E
K
L
Site 16
T165
G
L
R
Y
S
F
Q
T
P
E
K
L
Y
F
V
Site 17
Y170
F
Q
T
P
E
K
L
Y
F
V
L
D
Y
V
N
Site 18
Y199
L
E
P
R
A
R
F
Y
A
A
E
V
A
S
A
Site 19
T250
E
G
V
E
P
E
D
T
T
S
T
F
C
G
T
Site 20
T251
G
V
E
P
E
D
T
T
S
T
F
C
G
T
P
Site 21
S252
V
E
P
E
D
T
T
S
T
F
C
G
T
P
E
Site 22
T253
E
P
E
D
T
T
S
T
F
C
G
T
P
E
Y
Site 23
T257
T
T
S
T
F
C
G
T
P
E
Y
L
A
P
E
Site 24
Y271
E
V
L
R
K
E
P
Y
D
R
A
V
D
W
W
Site 25
Y285
W
C
L
G
A
V
L
Y
E
M
L
H
G
L
P
Site 26
Y295
L
H
G
L
P
P
F
Y
S
Q
D
V
S
Q
M
Site 27
S296
H
G
L
P
P
F
Y
S
Q
D
V
S
Q
M
Y
Site 28
Y303
S
Q
D
V
S
Q
M
Y
E
N
I
L
H
Q
P
Site 29
S339
D
Q
R
Q
R
L
G
S
K
A
D
F
L
E
I
Site 30
Y361
P
I
N
W
D
D
L
Y
H
K
R
L
T
P
P
Site 31
T366
D
L
Y
H
K
R
L
T
P
P
F
N
P
N
V
Site 32
S394
T
Q
E
A
V
S
K
S
I
G
C
T
P
D
T
Site 33
T398
V
S
K
S
I
G
C
T
P
D
T
V
A
S
S
Site 34
S404
C
T
P
D
T
V
A
S
S
S
G
A
S
S
A
Site 35
S405
T
P
D
T
V
A
S
S
S
G
A
S
S
A
F
Site 36
S416
S
S
A
F
L
G
F
S
Y
A
P
E
D
D
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation