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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VEZT
Full Name:
Vezatin
Alias:
Type:
Plasma membrane, Acrosome, Nucleus, Cell junction, Integral membrane protein
Mass (Da):
88665
Number AA:
779
UniProt ID:
Q9HBM0
International Prot ID:
IPI00029954
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0001669
GO:0005912
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
E
E
V
V
F
E
N
S
P
L
Y
Q
Y
L
Q
Site 2
Y17
V
F
E
N
S
P
L
Y
Q
Y
L
Q
D
L
G
Site 3
Y19
E
N
S
P
L
Y
Q
Y
L
Q
D
L
G
H
T
Site 4
S33
T
D
F
E
I
C
S
S
L
S
P
K
T
E
K
Site 5
S35
F
E
I
C
S
S
L
S
P
K
T
E
K
C
T
Site 6
T38
C
S
S
L
S
P
K
T
E
K
C
T
T
E
G
Site 7
T43
P
K
T
E
K
C
T
T
E
G
Q
Q
K
P
P
Site 8
T51
E
G
Q
Q
K
P
P
T
R
V
L
P
K
Q
G
Site 9
S94
D
I
G
F
R
L
D
S
L
H
T
I
L
Q
Q
Site 10
S121
L
L
D
P
S
I
L
S
A
G
Q
S
Q
Q
Q
Site 11
S125
S
I
L
S
A
G
Q
S
Q
Q
Q
E
N
G
H
Site 12
T196
R
T
A
K
L
Q
V
T
L
K
K
Y
S
V
H
Site 13
T209
V
H
L
E
D
M
A
T
N
S
R
A
F
T
N
Site 14
S211
L
E
D
M
A
T
N
S
R
A
F
T
N
L
V
Site 15
T215
A
T
N
S
R
A
F
T
N
L
V
R
K
A
L
Site 16
S252
N
K
A
G
Q
H
P
S
Q
H
L
I
G
L
R
Site 17
Y263
I
G
L
R
K
A
V
Y
R
T
L
R
A
N
F
Site 18
T265
L
R
K
A
V
Y
R
T
L
R
A
N
F
Q
A
Site 19
Y284
T
L
Y
M
L
K
N
Y
P
L
N
S
E
S
D
Site 20
S288
L
K
N
Y
P
L
N
S
E
S
D
N
V
T
N
Site 21
S290
N
Y
P
L
N
S
E
S
D
N
V
T
N
Y
I
Site 22
T294
N
S
E
S
D
N
V
T
N
Y
I
C
V
V
P
Site 23
Y296
E
S
D
N
V
T
N
Y
I
C
V
V
P
F
K
Site 24
S310
K
E
L
G
L
G
L
S
E
E
Q
I
S
E
E
Site 25
S315
G
L
S
E
E
Q
I
S
E
E
E
A
H
N
F
Site 26
S342
F
Q
L
W
V
A
Q
S
S
E
F
F
R
R
L
Site 27
S354
R
R
L
A
L
L
L
S
T
A
N
S
P
P
G
Site 28
T365
S
P
P
G
P
L
L
T
P
A
L
L
P
H
R
Site 29
S386
Q
G
L
P
H
A
H
S
A
C
L
E
E
L
K
Site 30
Y396
L
E
E
L
K
R
S
Y
E
F
Y
R
Y
F
E
Site 31
Y399
L
K
R
S
Y
E
F
Y
R
Y
F
E
T
Q
H
Site 32
Y401
R
S
Y
E
F
Y
R
Y
F
E
T
Q
H
Q
S
Site 33
S414
Q
S
V
P
Q
C
L
S
K
T
Q
Q
K
S
R
Site 34
T416
V
P
Q
C
L
S
K
T
Q
Q
K
S
R
E
L
Site 35
S420
L
S
K
T
Q
Q
K
S
R
E
L
N
N
V
H
Site 36
T428
R
E
L
N
N
V
H
T
A
V
R
S
L
Q
L
Site 37
Y468
Q
E
L
V
S
E
A
Y
P
I
L
E
Q
K
L
Site 38
S494
N
C
W
E
E
A
I
S
Q
V
D
K
L
L
R
Site 39
T504
D
K
L
L
R
R
N
T
D
K
K
G
K
P
E
Site 40
T520
A
C
E
N
P
H
C
T
V
V
P
L
K
Q
P
Site 41
Y546
E
E
Q
E
L
E
A
Y
V
D
D
I
D
I
D
Site 42
S554
V
D
D
I
D
I
D
S
D
F
R
K
D
D
F
Site 43
Y562
D
F
R
K
D
D
F
Y
Y
L
S
Q
E
D
K
Site 44
Y563
F
R
K
D
D
F
Y
Y
L
S
Q
E
D
K
E
Site 45
S565
K
D
D
F
Y
Y
L
S
Q
E
D
K
E
R
Q
Site 46
S579
Q
K
R
E
H
E
E
S
K
R
V
L
Q
E
L
Site 47
S595
S
V
L
G
F
K
A
S
E
A
E
R
Q
K
W
Site 48
S608
K
W
K
Q
L
L
F
S
D
H
A
V
L
K
S
Site 49
S615
S
D
H
A
V
L
K
S
L
S
P
V
D
P
V
Site 50
S617
H
A
V
L
K
S
L
S
P
V
D
P
V
E
P
Site 51
S626
V
D
P
V
E
P
I
S
N
S
E
P
S
M
N
Site 52
S628
P
V
E
P
I
S
N
S
E
P
S
M
N
S
D
Site 53
S631
P
I
S
N
S
E
P
S
M
N
S
D
M
G
K
Site 54
S634
N
S
E
P
S
M
N
S
D
M
G
K
V
S
K
Site 55
T644
G
K
V
S
K
N
D
T
E
E
E
S
N
K
S
Site 56
S651
T
E
E
E
S
N
K
S
A
T
T
D
N
E
I
Site 57
T661
T
D
N
E
I
S
R
T
E
Y
L
C
E
N
S
Site 58
Y663
N
E
I
S
R
T
E
Y
L
C
E
N
S
L
E
Site 59
S677
E
G
K
N
K
D
N
S
S
N
E
V
F
P
Q
Site 60
S678
G
K
N
K
D
N
S
S
N
E
V
F
P
Q
G
Site 61
Y692
G
A
E
E
R
M
C
Y
Q
C
E
S
E
D
E
Site 62
T708
Q
A
D
G
S
G
L
T
T
A
P
P
T
P
R
Site 63
T709
A
D
G
S
G
L
T
T
A
P
P
T
P
R
D
Site 64
T713
G
L
T
T
A
P
P
T
P
R
D
S
L
Q
P
Site 65
S717
A
P
P
T
P
R
D
S
L
Q
P
S
I
K
Q
Site 66
S721
P
R
D
S
L
Q
P
S
I
K
Q
R
L
A
R
Site 67
S732
R
L
A
R
L
Q
L
S
P
D
F
T
F
T
A
Site 68
S751
E
V
A
A
R
S
L
S
F
T
T
M
Q
E
Q
Site 69
T753
A
A
R
S
L
S
F
T
T
M
Q
E
Q
T
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation