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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BRF2
Full Name:
Transcription factor IIIB 50 kDa subunit
Alias:
BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like; BRFU; FLJ11052; RNA polymerase III transcription initiation factor BRF2; TFIIIB50; Transcription factor IIB-related factor, TFIIIB50
Type:
Mass (Da):
46533
Number AA:
419
UniProt ID:
Q9HAW0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0030528
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006352
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
G
R
C
P
D
C
G
S
T
E
L
V
E
D
S
Site 2
S19
S
T
E
L
V
E
D
S
H
Y
S
Q
S
Q
L
Site 3
Y21
E
L
V
E
D
S
H
Y
S
Q
S
Q
L
V
C
Site 4
S22
L
V
E
D
S
H
Y
S
Q
S
Q
L
V
C
S
Site 5
S24
E
D
S
H
Y
S
Q
S
Q
L
V
C
S
D
C
Site 6
T43
T
E
G
V
L
T
T
T
F
S
D
E
G
N
L
Site 7
S45
G
V
L
T
T
T
F
S
D
E
G
N
L
R
E
Site 8
T54
E
G
N
L
R
E
V
T
Y
S
R
S
T
G
E
Site 9
Y55
G
N
L
R
E
V
T
Y
S
R
S
T
G
E
N
Site 10
S56
N
L
R
E
V
T
Y
S
R
S
T
G
E
N
E
Site 11
T59
E
V
T
Y
S
R
S
T
G
E
N
E
Q
V
S
Site 12
S66
T
G
E
N
E
Q
V
S
R
S
Q
Q
R
G
L
Site 13
S68
E
N
E
Q
V
S
R
S
Q
Q
R
G
L
R
R
Site 14
S104
Y
Q
Q
A
Y
R
H
S
G
I
R
A
A
R
L
Site 15
S186
S
F
K
L
F
Q
A
S
P
S
V
P
A
K
Y
Site 16
S188
K
L
F
Q
A
S
P
S
V
P
A
K
Y
V
E
Site 17
Y193
S
P
S
V
P
A
K
Y
V
E
D
K
E
K
M
Site 18
S202
E
D
K
E
K
M
L
S
R
T
M
Q
L
V
E
Site 19
T218
A
N
E
T
W
L
V
T
G
R
H
P
L
P
V
Site 20
S236
A
T
F
L
A
W
Q
S
L
Q
P
A
D
R
L
Site 21
Y260
L
A
N
V
D
L
P
Y
P
A
S
S
R
L
Q
Site 22
S263
V
D
L
P
Y
P
A
S
S
R
L
Q
E
L
L
Site 23
S292
V
L
R
L
D
K
R
S
V
V
K
H
I
G
D
Site 24
S306
D
L
L
Q
H
R
Q
S
L
V
R
S
A
F
R
Site 25
S310
H
R
Q
S
L
V
R
S
A
F
R
D
G
T
A
Site 26
T316
R
S
A
F
R
D
G
T
A
E
V
E
T
R
E
Site 27
S342
E
G
E
V
G
N
N
S
L
G
L
P
Q
G
K
Site 28
S353
P
Q
G
K
R
P
A
S
P
A
L
L
L
P
P
Site 29
S365
L
P
P
C
M
L
K
S
P
K
R
I
C
P
V
Site 30
S385
V
T
G
D
E
N
I
S
D
S
E
I
E
Q
Y
Site 31
S387
G
D
E
N
I
S
D
S
E
I
E
Q
Y
L
R
Site 32
Y392
S
D
S
E
I
E
Q
Y
L
R
T
P
Q
E
V
Site 33
T395
E
I
E
Q
Y
L
R
T
P
Q
E
V
R
D
F
Site 34
S414
A
A
R
Q
A
A
T
S
V
P
N
P
P
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation