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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MLXIP
Full Name:
MLX-interacting protein
Alias:
bHLHe36; KIAA0867; MIR; MLX interacting protein; MLX-interacting; MONDOA; transcriptional activator MondoA
Type:
Mass (Da):
101190
Number AA:
UniProt ID:
Q9HAP2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005741
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0030528
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
A
D
V
F
M
C
S
P
R
R
P
R
S
R
Site 2
S15
C
S
P
R
R
P
R
S
R
G
R
Q
V
L
L
Site 3
S27
V
L
L
K
P
Q
V
S
E
D
D
D
D
S
D
Site 4
S33
V
S
E
D
D
D
D
S
D
T
D
E
P
S
P
Site 5
T35
E
D
D
D
D
S
D
T
D
E
P
S
P
P
P
Site 6
S39
D
S
D
T
D
E
P
S
P
P
P
A
S
G
A
Site 7
S44
E
P
S
P
P
P
A
S
G
A
A
T
P
A
R
Site 8
T48
P
P
A
S
G
A
A
T
P
A
R
A
H
A
S
Site 9
S55
T
P
A
R
A
H
A
S
A
A
P
P
P
P
R
Site 10
S79
R
R
Q
Q
I
I
H
S
G
H
F
M
V
S
S
Site 11
S86
S
G
H
F
M
V
S
S
P
H
R
E
H
P
P
Site 12
T101
K
K
G
Y
D
F
D
T
V
N
K
Q
T
C
Q
Site 13
S111
K
Q
T
C
Q
T
Y
S
F
G
K
T
S
S
C
Site 14
T115
Q
T
Y
S
F
G
K
T
S
S
C
H
L
S
I
Site 15
S116
T
Y
S
F
G
K
T
S
S
C
H
L
S
I
D
Site 16
S117
Y
S
F
G
K
T
S
S
C
H
L
S
I
D
A
Site 17
S121
K
T
S
S
C
H
L
S
I
D
A
S
L
T
K
Site 18
S143
A
Y
S
G
K
L
V
S
P
K
W
K
N
F
K
Site 19
S192
F
V
T
P
L
D
G
S
V
D
V
D
E
H
R
Site 20
T205
H
R
R
P
E
A
I
T
T
E
G
K
Y
W
K
Site 21
T206
R
R
P
E
A
I
T
T
E
G
K
Y
W
K
S
Site 22
S213
T
E
G
K
Y
W
K
S
R
I
E
I
V
I
R
Site 23
Y222
I
E
I
V
I
R
E
Y
H
K
W
R
T
Y
F
Site 24
Y228
E
Y
H
K
W
R
T
Y
F
K
K
R
L
Q
Q
Site 25
S243
H
K
D
E
D
L
S
S
L
V
Q
D
D
D
M
Site 26
Y252
V
Q
D
D
D
M
L
Y
W
H
K
H
G
D
G
Site 27
T262
K
H
G
D
G
W
K
T
P
V
P
M
E
E
D
Site 28
T274
E
E
D
P
L
L
D
T
D
M
L
M
S
E
F
Site 29
S287
E
F
S
D
T
L
F
S
T
L
S
S
H
Q
P
Site 30
T288
F
S
D
T
L
F
S
T
L
S
S
H
Q
P
V
Site 31
S290
D
T
L
F
S
T
L
S
S
H
Q
P
V
A
W
Site 32
S291
T
L
F
S
T
L
S
S
H
Q
P
V
A
W
P
Site 33
T328
P
N
L
D
F
M
D
T
F
E
P
F
Q
D
L
Site 34
S337
E
P
F
Q
D
L
F
S
S
S
R
S
I
F
G
Site 35
S338
P
F
Q
D
L
F
S
S
S
R
S
I
F
G
S
Site 36
S339
F
Q
D
L
F
S
S
S
R
S
I
F
G
S
M
Site 37
S345
S
S
R
S
I
F
G
S
M
L
P
A
S
A
S
Site 38
S352
S
M
L
P
A
S
A
S
A
P
V
P
D
P
N
Site 39
S366
N
N
P
P
A
Q
E
S
I
L
P
T
T
A
L
Site 40
S390
I
A
P
P
T
A
P
S
L
A
H
M
D
E
Q
Site 41
T405
G
C
E
H
T
S
R
T
E
D
P
F
I
Q
P
Site 42
T413
E
D
P
F
I
Q
P
T
D
F
G
P
S
E
P
Site 43
S418
Q
P
T
D
F
G
P
S
E
P
P
L
S
V
P
Site 44
S423
G
P
S
E
P
P
L
S
V
P
Q
P
F
L
P
Site 45
T467
L
N
P
P
A
P
P
T
F
H
Q
P
Q
K
F
Site 46
T493
H
T
A
S
A
T
L
T
H
D
A
P
A
T
T
Site 47
T499
L
T
H
D
A
P
A
T
T
F
S
Q
S
Q
G
Site 48
T500
T
H
D
A
P
A
T
T
F
S
Q
S
Q
G
L
Site 49
T511
S
Q
G
L
V
I
T
T
H
H
P
A
P
S
A
Site 50
S517
T
T
H
H
P
A
P
S
A
A
P
C
G
L
A
Site 51
T529
G
L
A
L
S
P
V
T
R
P
P
Q
P
R
L
Site 52
T537
R
P
P
Q
P
R
L
T
F
V
H
P
K
P
V
Site 53
S545
F
V
H
P
K
P
V
S
L
T
G
G
R
P
K
Site 54
S567
A
P
K
P
E
P
V
S
L
V
L
K
N
A
R
Site 55
S602
K
R
E
G
M
L
A
S
T
V
S
Q
S
N
V
Site 56
T603
R
E
G
M
L
A
S
T
V
S
Q
S
N
V
V
Site 57
S639
T
D
L
G
H
G
T
S
S
P
P
A
P
V
S
Site 58
S640
D
L
G
H
G
T
S
S
P
P
A
P
V
S
R
Site 59
S646
S
S
P
P
A
P
V
S
R
L
F
P
S
T
A
Site 60
S651
P
V
S
R
L
F
P
S
T
A
Q
D
P
L
G
Site 61
T652
V
S
R
L
F
P
S
T
A
Q
D
P
L
G
K
Site 62
S669
Q
V
P
L
H
G
G
S
P
Q
V
T
V
T
G
Site 63
T673
H
G
G
S
P
Q
V
T
V
T
G
P
S
R
D
Site 64
S684
P
S
R
D
C
P
N
S
G
Q
A
S
P
C
A
Site 65
S688
C
P
N
S
G
Q
A
S
P
C
A
S
E
Q
S
Site 66
S692
G
Q
A
S
P
C
A
S
E
Q
S
P
S
P
Q
Site 67
S695
S
P
C
A
S
E
Q
S
P
S
P
Q
S
P
Q
Site 68
S697
C
A
S
E
Q
S
P
S
P
Q
S
P
Q
N
N
Site 69
S700
E
Q
S
P
S
P
Q
S
P
Q
N
N
C
S
G
Site 70
S706
Q
S
P
Q
N
N
C
S
G
K
S
D
P
K
N
Site 71
S709
Q
N
N
C
S
G
K
S
D
P
K
N
V
A
A
Site 72
S747
D
M
L
N
S
L
I
S
N
N
S
K
L
T
S
Site 73
S750
N
S
L
I
S
N
N
S
K
L
T
S
H
A
I
Site 74
S754
S
N
N
S
K
L
T
S
H
A
I
T
L
Q
K
Site 75
T758
K
L
T
S
H
A
I
T
L
Q
K
T
V
E
Y
Site 76
T804
C
Q
Q
L
L
P
A
T
G
V
P
V
T
R
R
Site 77
T809
P
A
T
G
V
P
V
T
R
R
Q
F
D
H
M
Site 78
Y823
M
K
D
M
F
D
E
Y
V
K
T
R
T
L
Q
Site 79
S853
E
S
F
K
G
M
V
S
T
S
S
L
E
E
L
Site 80
S855
F
K
G
M
V
S
T
S
S
L
E
E
L
H
R
Site 81
S856
K
G
M
V
S
T
S
S
L
E
E
L
H
R
T
Site 82
T863
S
L
E
E
L
H
R
T
A
L
S
W
L
D
Q
Site 83
S866
E
L
H
R
T
A
L
S
W
L
D
Q
H
C
S
Site 84
T890
S
T
L
R
Q
L
S
T
S
T
S
I
L
T
D
Site 85
S891
T
L
R
Q
L
S
T
S
T
S
I
L
T
D
P
Site 86
S893
R
Q
L
S
T
S
T
S
I
L
T
D
P
A
Q
Site 87
S906
A
Q
L
P
E
Q
A
S
K
A
V
T
R
I
G
Site 88
T910
E
Q
A
S
K
A
V
T
R
I
G
K
R
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation